Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lucy C. Wright"'
Autor:
Angharad N. de Cates, Lucy C. Wright, Marieke A. G. Martens, Daisy Gibson, Cagdas Türkmen, Nicola Filippini, Philip J. Cowen, Catherine J. Harmer, Susannah E. Murphy
Publikováno v:
Translational Psychiatry, Vol 11, Iss 1, Pp 1-9 (2021)
Abstract Cognitive deficits commonly accompany psychiatric disorders but are often underrecognised, and difficult to treat. The 5-HT4 receptor is a promising potential treatment target for cognitive impairment because in animal studies 5-HT4 receptor
Externí odkaz:
https://doaj.org/article/d7753ba1fec942c5b17a086a3665f019
Autor:
Angharad N. de Cates, Marieke A. G. Martens, Lucy C. Wright, Cassandra D. Gould van Praag, Liliana P. Capitão, Daisy Gibson, Philip J. Cowen, Catherine J. Harmer, Susannah E. Murphy
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Depression is a common and often recurrent illness with significant negative impact on a global scale. Current antidepressants are ineffective for up to one third of people with depression, many of whom experience persistent symptomatology. 5-HT4 rec
Externí odkaz:
https://doaj.org/article/50741c33909541cfba484943a7f7c037
Publikováno v:
BMJ Open, Vol 13, Iss 12 (2023)
Objectives This study aims to map existing literature describing how people with lived experience of self-harm have engaged in codesigning self-harm interventions, understand barriers and facilitators to this engagement, and how the meaningfulness of
Externí odkaz:
https://doaj.org/article/aed609fbb8cf412d83b7eeb93f4c3909
Publikováno v:
Journal of Psychiatric Research. 158:226-230
Adverse childhood experiences are significantly associated with a worse clinical expression of bipolar disorder, however, the literature has mainly focused on childhood maltreatment (abuse and neglect) with little attention paid to other forms of adv
Autor:
Angharad N. de Cates, Marieke A.G. Martens, Lucy C. Wright, Daisy Gibson, Gershon Spitz, Cassandra D. Gould van Praag, Sana Suri, Philip J. Cowen, Susannah E. Murphy, Catherine J. Harmer
Publikováno v:
Biological Psychiatry: Cognitive Neuroscience and Neuroimaging.
Autor:
Susannah E, Murphy, Angharad N, de Cates, Amy L, Gillespie, Beata R, Godlewska, Jessica C, Scaife, Lucy C, Wright, Philip J, Cowen, Catherine J, Harmer
Publikováno v:
Psychological Medicine
Animal experimental studies suggest that 5-HT4 receptor activation holds promise as a novel target for the treatment of depression and cognitive impairment. 5-HT4 receptors are post-synaptic receptors that are located in striatal and limbic areas kno
Publikováno v:
Psychological medicine. 50(16)
5-HT4 receptor stimulation has pro-cognitive and antidepressant-like effects in animal experimental studies; however, this pharmacological approach has not yet been tested in humans. Here we used the 5-HT4 receptor partial agonist prucalopride to ass