Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lucy C. K. Bell"'
Autor:
Rachel Byng-Maddick, Carolin T. Turner, Gabriele Pollara, Matthew Ellis, Naomi J. Guppy, Lucy C. K. Bell, Michael R. Ehrenstein, Mahdad Noursadeghi
Publikováno v:
Frontiers in Immunology, Vol 8 (2017)
The impact of anti-tumor necrosis factor (TNF) therapies on inducible TNF-dependent activity in humans has never been evaluated in vivo. We aimed to test the hypothesis that patients responding to anti-TNF treatments exhibit attenuated TNF-dependent
Externí odkaz:
https://doaj.org/article/c22d2d58da354ddfbab38abe151315d1
Autor:
Paula I Seoane, Leanne M Taylor-Smith, David Stirling, Lucy C K Bell, Mahdad Noursadeghi, Dalan Bailey, Robin C May
Publikováno v:
PLoS Pathogens, Vol 16, Iss 2, p e1008240 (2020)
Cryptococcus neoformans is an opportunistic human pathogen, which causes serious disease in immunocompromised hosts. Infection with this pathogen is particularly relevant in HIV+ patients, where it leads to around 200,000 deaths per annum. A key feat
Externí odkaz:
https://doaj.org/article/d5be591f45d14f6cb1ef65d844e47cdb
Autor:
Lucy C K Bell, Sarah Logan, Tim Baruah, David Lanham, Melissa Heightman, Gabriella Bidwell, Michael Marks, Akish Luintel, Caitlin Norris-Grey, Luke O'Shea
Publikováno v:
Clin Med (Lond)
The COVID-19 pandemic has necessitated rapid adaptation of healthcare providers to new clinical and logistical challenges. Following identification of high levels of emergency department (ED) reattendance among patients with suspected COVID-19 at our
Autor:
Lucy C K Bell, Gabriele Pollara, Mellissa Pascoe, Gillian S Tomlinson, Rannakoe J Lehloenya, Jennifer Roe, Richard Meldau, Robert F Miller, Alan Ramsay, Benjamin M Chain, Keertan Dheda, Mahdad Noursadeghi
Publikováno v:
PLoS Pathogens, Vol 12, Iss 3, p e1005469 (2016)
Increased risk of tuberculosis (TB) associated with HIV-1 infection is primarily attributed to deficient T helper (Th)1 immune responses, but most people with active TB have robust Th1 responses, indicating that these are not sufficient to protect ag
Externí odkaz:
https://doaj.org/article/2756ecfddd6448d2884a1415dc005b6c
Autor:
Catherine F Houlihan, Michael Marks, Geraldine O’Hara, Melissa Heightman, Nicholas Hart, Lucy C K Bell
COVID-19, caused by SARS-CoV-2, is an emerging viral respiratory pathogen. The disease was first described in China in 2019, likely emerging as a zoonosis, before spreading worldwide to cause a severe global pandemic in 2020. COVID-19 is transmitted
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4e8b24c38d1701e55f7e929c7e76e8d5
https://doi.org/10.1016/b978-0-08-102723-3.00139-6
https://doi.org/10.1016/b978-0-08-102723-3.00139-6
Autor:
Gabriele Pollara, Tommy Rampling, Imogen Jones, Lucy C K Bell, Sarah Logan, Michael Marks, Stephen Morris-Jones, Katharina Kranzer
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
The OVIVA study demonstrated noninferiority for managing bone and joint infections (BJIs) with oral antibiotics. We report that 79.7% of OPAT patients being treated for BJIs at our center would be eligible for oral antibiotics, saving a median (IQR)
Autor:
Lucy C K Bell, Gabriele Pollara
Publikováno v:
JAMA Internal Medicine.
Autor:
Hibba Kurdi, Matthew Whelan, Gabriele Pollara, Jonathan Lambourne, James C. Moon, Rosemary J. Boyton, José Afonso Guerra-Assunção, Jessica Artico, Joshua Rosenheim, Daniel M. Altmann, Mahdad Noursadeghi, Teresa Cutino-Moguel, Thomas A. Treibel, Aneesh Chandran, Charlotte Manisty, Mala K. Maini, Lucy C K Bell, George Joy, Rishi K Gupta, Áine McKnight, Benjamin M. Chain
We hypothesised that host-response biomarkers of viral infections may contribute to early identification of SARS-CoV-2 infected individuals, critical to breaking chains of transmission. We identified 20 candidate blood transcriptomic signatures of vi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8514009da5103595a5d6ec5c7bc98211
https://doi.org/10.1101/2021.01.18.21250044
https://doi.org/10.1101/2021.01.18.21250044
Autor:
Lucy C K Bell, Gabriele Pollara, Daniel Butler, Sagi Shapira, Jonathan Foox, Christopher E. Mason, Jacob Kim, Cem Meydan, Mahdad Noursadeghi
Publikováno v:
iScience
bioRxiv
article-version (status) pre
article-version (number) 2
iScience, Vol 24, Iss 1, Pp 101896-(2021)
bioRxiv
article-version (status) pre
article-version (number) 2
iScience, Vol 24, Iss 1, Pp 101896-(2021)
Dysregulated IL-1β and IL-6 responses have been implicated in the pathogenesis of severe Coronavirus Disease 2019 (COVID-19). Innovative approaches for evaluating the biological activity of these cytokines in vivo are urgently needed to complement c
Publikováno v:
BMJ
Glasziou and colleagues discuss the waste in covid-19 research that amplifies pre-existing failures.1 We think the situation goes beyond waste. Delaying publication of trial results after data have been collected and analysed is unethical. It leads t