Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Lucy A. Ward"'
Autor:
Julie A. Ake, Kristopher Paolino, Jack N. Hutter, Susan Biggs Cicatelli, Leigh Anne Eller, Michael A. Eller, Margaret C. Costanzo, Dominic Paquin-Proulx, Merlin L. Robb, Chi L. Tran, Lalaine Anova, Linda L. Jagodzinski, Lucy A. Ward, Nicole Kilgore, Janice Rusnak, Callie Bounds, Christopher S. Badorrek, Jay W. Hooper, Steven A. Kwilas, Ine Ilsbroux, Dickson Nkafu Anumendem, Auguste Gaddah, Georgi Shukarev, Viki Bockstal, Kerstin Luhn, Macaya Douoguih, Cynthia Robinson
Publikováno v:
Vaccines, Vol 12, Iss 5, p 497 (2024)
The safety and immunogenicity of the two-dose Ebola vaccine regimen MVA-BN-Filo, Ad26.ZEBOV, 14 days apart, was evaluated in people without HIV (PWOH) and living with HIV (PLWH). In this observer-blind, placebo-controlled, phase 2 trial, healthy adul
Externí odkaz:
https://doaj.org/article/d508ae26d5664c20827179054ade0b7e
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1216 (2022)
The cynomolgus monkey (Macaca fascicularis) non-human primate (NHP) is widely used for filovirus vaccine testing. To use limited BSL-4 resources efficiently and minimize NHP usage, Simon’s two-stage design was adapted to screen candidate Ebola viru
Externí odkaz:
https://doaj.org/article/1e9e23501454433e9587e7d70f938cde
Autor:
Kimberly L. Taylor, Lynda Lanning, Lawrence Wolfraim, Sonia Shrivastava Gales, Colleen Sico, William E. Dowling, Lucy A. Ward, William C. Florence, Edwin Nuzum, Paula R. Bryant
Publikováno v:
Vaccines, Vol 10, Iss 8, p 1201 (2022)
A United States Government (USG) interagency group, the Filovirus Animal Non-Clinical Group (FANG), has been established to support the development of biodefense medical countermeasures (MCMs). As both vaccines and therapeutics are licensed using “
Externí odkaz:
https://doaj.org/article/4b194295333c4b05a972675047f16580
Autor:
Daniel N. Wolfe, Carol L. Sabourin, Michael J. Merchlinsky, William C. Florence, Larry A. Wolfraim, Kimberly L. Taylor, Lucy A. Ward
Publikováno v:
Vaccines, Vol 9, Iss 9, p 1045 (2021)
The continuing outbreaks of ebola virus disease highlight the ongoing threat posed by filoviruses. Fortunately, licensed vaccines and therapeutics are now available for Zaire ebolavirus. However, effective medical countermeasures, such as vaccines fo
Externí odkaz:
https://doaj.org/article/73596e1a6cfd4c0db6c1fc5902d3557b
Autor:
Rona Hirschberg, Lucy A. Ward, Nicole Kilgore, Rebecca Kurnat, Helen Schiltz, Mark T. Albrecht, George W. Christopher, Ed Nuzum
Publikováno v:
Viruses, Vol 6, Iss 7, Pp 2673-2697 (2014)
On August 22–23, 2013, agencies within the United States Department of Defense (DoD) and the Department of Health and Human Services (HHS) sponsored the Filovirus Medical Countermeasures (MCMs) Workshop as an extension of the activities of the Filo
Externí odkaz:
https://doaj.org/article/f2ff560aaf2146da970b38c57ebf54d3
Autor:
Janice M. Rusnak, Pamela J. Glass, Scott C. Weaver, Carol L. Sabourin, Andrew M. Glenn, William Klimstra, Christopher S. Badorrek, Farooq Nasar, Lucy A. Ward
Publikováno v:
Viruses, Vol 11, Iss 9, p 807 (2019)
Licensure of a vaccine to protect against aerosolized Venezuelan equine encephalitis virus (VEEV) requires use of the U.S. Food and Drug Administration (FDA) Animal Rule to assess vaccine efficacy as human studies are not feasible or ethical. An appr
Externí odkaz:
https://doaj.org/article/135a5c3ffec4495cb89500564d751b9d
Autor:
Lucy C. Ward, Ellie Goulding, Daniel J. Rigden, Faye E. Allan, Alessandro Pellis, Harry Hatton, Georg M. Guebitz, J. Enrique Salcedo-Sora, Andrew J Carnell
Publikováno v:
ChemSusChem.
Autor:
Lucy C. Ward, Hannah V. McCue, Daniel J. Rigden, Neil M. Kershaw, Chloe Ashbrook, Harry Hatton, Ellie Goulding, James R. Johnson, Andrew J. Carnell
Publikováno v:
Angewandte Chemie
Carboxyl methyltransferase (CMT) enzymes catalyse the biomethylation of carboxylic acids under aqueous conditions and have potential for use in synthetic enzyme cascades. Herein we report that the enzyme FtpM from Aspergillus fumigatus can methylate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a548240c0195a377882143e2f91c6856
Publikováno v:
ChemCatChem. 13:121-128
Autor:
Lucy A Ward, Aysegul Nalca, Ricardo Carrion, Trevor Brasel, Arthur J. Goff, Hilary M. Staples, Alisha Rajbhandari, Margaret L. Pitt, Andrew Kocsis, John Trefry, Anthony Griffiths, Jason E. Comer, Cheryl A. Triplett, Nancy A. Niemuth, Clint Florence, Kendra J. Alfson, Dawn Fallacara, Amy C. Shurtleff, Shane Massey, Jake Lowry, Michael P. Fay, Sanjay M. Tamrakar, Yenny Goez-Gazi, Jeanon N. Smith, Sara C. Johnston
Publikováno v:
PLoS ONE
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
PLoS ONE, Vol 16, Iss 7, p e0252874 (2021)
Filoviruses (Family Filoviridae genera Ebolavirus and Marburgvirus) are negative-stranded RNA viruses that cause severe health effects in humans and non-human primates, including death. Except in outbreak settings, vaccines and other medical counterm