Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lucy A. Stebbings"'
Autor:
Benjamin JM Taylor, Serena Nik-Zainal, Yee Ling Wu, Lucy A Stebbings, Keiran Raine, Peter J Campbell, Cristina Rada, Michael R Stratton, Michael S Neuberger
Publikováno v:
eLife, Vol 2 (2013)
Breast cancer genomes have revealed a novel form of mutation showers (kataegis) in which multiple same-strand substitutions at C:G pairs spaced one to several hundred nucleotides apart are clustered over kilobase-sized regions, often associated with
Externí odkaz:
https://doaj.org/article/4f928046b5fd42ab80eb6bcc2a8dd96f
Autor:
Susan M Gribble, Frances K Wiseman, Stephen Clayton, Elena Prigmore, Elizabeth Langley, Fengtang Yang, Sean Maguire, Beiyuan Fu, Diana Rajan, Olivia Sheppard, Carol Scott, Heidi Hauser, Philip J Stephens, Lucy A Stebbings, Bee Ling Ng, Tomas Fitzgerald, Michael A Quail, Ruby Banerjee, Kai Rothkamm, Victor L J Tybulewicz, Elizabeth M C Fisher, Nigel P Carter
Publikováno v:
PLoS ONE, Vol 8, Iss 4, p e60482 (2013)
Down syndrome (DS) is caused by trisomy of chromosome 21 (Hsa21) and presents a complex phenotype that arises from abnormal dosage of genes on this chromosome. However, the individual dosage-sensitive genes underlying each phenotype remain largely un
Externí odkaz:
https://doaj.org/article/40d01f7c551e41a4a19b62b717840f84
Publikováno v:
Developmental Genetics. 24:57-68
Recent experiments have demonstrated that a family of proteins, known as the innexins, are structural components of invertebrate gap junctions. The shaking-B (shak-B) locus of Drosophila encodes two members of this emerging family, Shak-B(lethal) and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::53bd3e10d0fd660841e69cf59e2414c1
https://doi.org/10.1002/(sici)1520-6408(1999)24:1/2<57::aid-dvg7>3.0.co
https://doi.org/10.1002/(sici)1520-6408(1999)24:1/2<57::aid-dvg7>3.0.co
Autor:
Jane A. Davies, Pauline Phelan, Richard A. Baines, Chris Ford, Jonathan P. Bacon, Lucy A. Stebbings
Publikováno v:
Nature. 391:181-184
In most multicellular organisms direct cell–cell communication is mediated by the intercellular channels of gap junctions. These channels allow the exchange of ions and molecules that are believed to be essential for cell signalling during developm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac7b53428a73a61ea61bf6f28313ba40
https://doi.org/10.1038/34426
https://doi.org/10.1038/34426
Autor:
Kenji Mizuguchi, Lucy A. Stebbings
Publikováno v:
Nucleic acids research. 32
HOMSTRAD (http://www-cryst.bioc.cam.ac.uk/ homstrad/) is a collection of protein families, clustered on the basis of sequence and structural similarity. The database is unique in that the protein family sequence alignments have been specially annotat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76699e9a1da645c7029f10660cb27630
https://pubmed.ncbi.nlm.nih.gov/14681395
https://pubmed.ncbi.nlm.nih.gov/14681395
Autor:
Martin G. Todman, Kirsten Jacobs, Lucy A. Stebbings, Jennifer L.Y. Tam, Jonathan P. Bacon, Pauline Phelan, Claire E. Greer, Rose J Phillips, Jane A. Davies
Publikováno v:
Mechanisms of development. 113(2)
Invertebrate gap junctions are composed of proteins called innexins and eight innexin encoding loci have been identified in the now complete genome sequence of Drosophila melanogaster. The intercellular channels formed by these proteins are multimeri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02a5447e39b4bbe254b97789db69a177
https://pubmed.ncbi.nlm.nih.gov/11960713
https://pubmed.ncbi.nlm.nih.gov/11960713
Members of the innexin protein family are structural components of invertebrate gap junctions and are analogous to vertebrate connexins. Here we investigate two Drosophila innexin genes, Dm-inx2 and Dm-inx3 and show that they are expressed in overlap
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1bcea779984f9db4d3c4a80d12c4fc15
https://europepmc.org/articles/PMC14932/
https://europepmc.org/articles/PMC14932/
Autor:
Siegfried Hekimi, Jonathan P. Bacon, Thomas M. Barnes, Leon Avery, Richard A. Baines, Martin G. Todman, Kathryn D. Curtin, Jocelyn E. Shaw, Lucy A. Stebbings, Raymond Lee, Todd A. Starich, Jane A. Davies, Yi-An Sun, Pauline Phelan, Chris Ford, Robert J. Wyman
Publikováno v:
Trends in genetics : TIG. 14(9)
In vertebrates, intercellular communication via gap junctions is mediated by the connexin family of molecules, which is made up of at least 13 members (reviewed in Ref. 1). These proteins, which have four transmembrane domains and intracellular C- an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::078f8f42663593d3336d895e4c1c5883
https://pubmed.ncbi.nlm.nih.gov/9769729
https://pubmed.ncbi.nlm.nih.gov/9769729
Autor:
Andrew Menzies, Alistair G. Rust, John G. Anema, Adam Butler, Ville Mustonen, David A. Tuveson, Jon W. Teague, Meng-Lay Lin, David A. Largaespada, Peter J. Campbell, Keiran Raine, Claire Hardy, Stuart McLaren, Mingming Jia, Karl Dykema, Pedro A. Perez-Mancera, Stéphane Richard, Juok Cho, Patrick S. Tarpey, Andrej Fischer, Dachuan Huang, Graham R. Bignell, Ignacio Varela, John Marshall, Lucy A. Stebbings, Calli Latimer, Kyle A. Furge, Chutima Subimerb, Philip J. Stephens, Gillian L. Dalgliesh, P. Andrew Futreal, Helen Davies, Bin Tean Teh, Danushka Galappaththige, L. Wessels, David Jones, Laura Mudie, Waraporn Chan-on, KingWai Lau, Michael R. Stratton, Richard J. Kahnoski, Choon Kiat Ong, David J. Adams, Christopher Greenman
Publikováno v:
Nature. 484:130-130
Nature 469, 539–542 (2011) In this Letter, the accession number for the gene expression data in the Gene Expression Omnibus was wrongly published as GEO22316. The correct accession number is GSE22316. We thank P. Boutros for pointing this out. This
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4050473ac3b2fca7403b0d762190f301
https://doi.org/10.1038/nature11027
https://doi.org/10.1038/nature11027
Autor:
Gribble, Susan M.1 smg@sanger.ac.uk, Wiseman, Frances K.2, Clayton, Stephen1, Prigmore, Elena1, Langley, Elizabeth1, Yang, Fengtang1, Maguire, Sean1, Fu, Beiyuan1, Rajan, Diana1, Sheppard, Olivia2, Scott, Carol1, Hauser, Heidi1, Stephens, Philip J.1, Stebbings, Lucy A.1, Ng, Bee Ling1, Fitzgerald, Tomas1, Quail, Michael A.1, Banerjee, Ruby1, Rothkamm, Kai3, Tybulewicz, Victor L. J.4
Publikováno v:
PLoS ONE. Apr2013, Vol. 8 Issue 4, p1-10. 10p.