Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Lucy A. Ochola"'
Publikováno v:
Journal of Advanced Biotechnology and Experimental Therapeutics, Vol 7, Iss 2, Pp 396-407 (2024)
Enterohemorrhagic Escherichia coli (EHEC) generates Shiga toxins that causes immunosuppression and diarrhea. Synthetic immunomodulatory drugs are associated with numerous severe effects, necessitating the need for substitute therapeutic agents. This
Externí odkaz:
https://doaj.org/article/227e43b71f404f39ba7a910258476e20
Autor:
D Herbert Opi, Carolyne M Ndila, Sophie Uyoga, Alex W Macharia, Clare Fennell, Lucy B Ochola, Gideon Nyutu, Bethseba R Siddondo, John Ojal, Mohammed Shebe, Kennedy O Awuondo, Neema Mturi, Norbert Peshu, Benjamin Tsofa, Gavin Band, Kathryn Maitland, Dominic P Kwiatkowski, Kirk A Rockett, Thomas N Williams, J Alexandra Rowe
Publikováno v:
PLoS Genetics, Vol 19, Iss 9, p e1010910 (2023)
Blood group O is associated with protection against severe malaria and reduced size and stability of P. falciparum-host red blood cell (RBC) rosettes compared to non-O blood groups. Whether the non-O blood groups encoded by the specific ABO genotypes
Externí odkaz:
https://doaj.org/article/07fa8bb0e3a9466b93188d388f8991ef
Autor:
Ruth K. Lucinde, Daisy Mugo, Christian Bottomley, Angela Karani, Elizabeth Gardiner, Rabia Aziza, John N. Gitonga, Henry Karanja, James Nyagwange, James Tuju, Perpetual Wanjiku, Edward Nzomo, Evans Kamuri, Kaugiria Thuranira, Sarah Agunda, Gideon Nyutu, Anthony O. Etyang, Ifedayo M. O. Adetifa, Eunice Kagucia, Sophie Uyoga, Mark Otiende, Edward Otieno, Leonard Ndwiga, Charles N. Agoti, Rashid A. Aman, Mercy Mwangangi, Patrick Amoth, Kadondi Kasera, Amek Nyaguara, Wangari Ng’ang’a, Lucy B. Ochola, Emukule Namdala, Oscar Gaunya, Rosemary Okuku, Edwine Barasa, Philip Bejon, Benjamin Tsofa, L. Isabella Ochola-Oyier, George M. Warimwe, Ambrose Agweyu, J. Anthony G. Scott, Katherine E. Gallagher
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Introduction The high proportion of SARS-CoV-2 infections that have remained undetected presents a challenge to tracking the progress of the pandemic and estimating the extent of population immunity. Methods We used residual blood samples from women
Externí odkaz:
https://doaj.org/article/636b8270c74a4ef8b61b2553cefc91cf
Autor:
David B. Ouko, Peris W. Amwayi, Lucy A. Ochola, Peninah M. Wairagu, Alfred Orina Isaac, James N. Nyariki
Publikováno v:
J Parasit Dis
Development of cerebral malaria (CM) is driven by parasitemia levels, harmful inflammatory response, oxidative stress and consequent breach of the blood brain barrier. Use of adjunct therapy that utilizes an antioxidant and anti-inflammatory agent al
Autor:
D. Herbert Opi, Lucy B. Ochola, Metrine Tendwa, Bethsheba R. Siddondo, Harold Ocholla, Harry Fanjo, Ashfaq Ghumra, David J.P. Ferguson, J. Alexandra Rowe, Thomas N. Williams
Publikováno v:
EBioMedicine, Vol 1, Iss 1, Pp 29-36 (2014)
Background: Individually, the red blood cell (RBC) polymorphisms sickle cell trait (HbAS) and α+thalassemia protect against severe Plasmodium falciparum malaria. It has been shown through epidemiological studies that the co-inheritance of both condi
Externí odkaz:
https://doaj.org/article/b49fe2e2d808457da8390056ddfbc3f1
Autor:
Leonard Ndwiga, Shirine Voller, Kadondi Kasera, Rosemary Okuku, Anthony Etyang, Wangari Ng’ang’a, Ifedayo M. O. Adetifa, Nelson Kilimo, Thuranira Kaugiria, Katherine E. Gallagher, Ruth Lucinde, Mercy Mwangangi, Wycliffe Moracha, Philip Bejon, Ambrose Agweyu, Lucy B. Ochola, George M. Warimwe, Perpetual Wanjiku, Hosea Maroko, Justus Weru, Sophie Uyoga, Shadrack Mutua, James Tuju, J. Anthony G. Scott, David Mukabi, Barrack Angujo, Eddy Nzomo, Benjamin Tsofa, Rashid Aman, Namdala Emukule, Patrick Amoth, John N. Gitonga, Charles N. Agoti, Henry K. Karanja, Amek Nyaguara, Eric Maitha, Sande Charo, Christian Bottomley, Lynette Isabella Ochola-Oyier, Daisy Mugo, Edward Otieno, Monicah Ogutu, E Wangeci Kagucia, Evanson Kamuri, Mark Otiende, Angela Karani, David James Nokes, Edwine Barasa, Catherine Kalu, James Nyagwange
Publikováno v:
Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Background Few studies have assessed the seroprevalence of antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) among healthcare workers (HCWs) in Africa. We report findings from a survey among HCWs in 3 counties in Kenya.
Autor:
Lucy A. Ochola, Eric M. Guantai
Hyperglycemia is the elevation of blood glucose concentrations above the normal range. Prolonged uncontrolled hyperglycemia is associated with serious life-threatening complications. Hyperglycemia arises from an imbalance between glucose production a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::92f7bc6cbd966ff6ab24e48b67a5be66
https://mts.intechopen.com/articles/show/title/prevention-of-hyperglycemia
https://mts.intechopen.com/articles/show/title/prevention-of-hyperglycemia
Autor:
Lucy A. Ochola, Gabriel Buluku, Kennedy Muthoka, Mtebe Majigo, Peter Memiah, Lillian Nkinda, Felix Humwa, Zelalem T. Haile, Anne Kamau, Aisha Zuheri
Publikováno v:
BMC Public Health, Vol 21, Iss 1, Pp 1-11 (2021)
BMC Public Health
BMC Public Health
BackgroundHIV and mental disorders are predicted to be the leading causes of illness worldwide by the year 2030. HIV-infected patients are at increased risk of developing mental disorders which are significantly associated with negative clinical outc
Autor:
Ngalla E. Jillani, Alfred Orina Isaac, Nemwel O. Nyamweya, Peris Amwayi, James N. Nyariki, Laurent Azonvide, Lucy A. Ochola, Dorcas S. Yole
Publikováno v:
Parasitology International. 71:106-120
In animal model of experimental cerebral malaria (ECM), the genesis of neuropathology is associated with oxidative stress and inflammatory mediators. There is limited progress in the development of new approaches to the treatment of cerebral malaria.
Autor:
Anthony Etyang, Leonard Ndwiga, Catherine Kalu, J. Anthony G. Scott, Wycliffe Moracha, Kadondi Kasera, Namdala Emukule, Daisy Mugo, Edward Otieno, Monicah Ogutu, Eddy Nzomo, Lucy B. Ochola, Wangari Ng’ang’a, Rashid Aman, Katherine E. Gallagher, Sophie Uyoga, James Nyagwange, Eric Maitha, Sande Charo, Thuranira Kaugiria, Justus Weru, Angela Karani, Evanson Kamuri, Barrack Angujo, Philip Bejon, David Mukabi, Ifedayo M. O. Adetifa, John N. Gitonga, Mark Otiende, Shirine Voller, Benjamin Tsofa, Rosemary Okuku, E Wangeci Kagucia, George M. Warimwe, Patrick Amoth, Christian Bottomley, Charles N. Agoti, Amek Nyaguara, Edwine Barasa, Shadrack Mutua, David James Nokes, Ruth Lucinde, Henry K. Karanja, Mercy Mwangangi, Lynette Isabella Ochola-Oyier, James Tuju, Ambrose Agweyu, Perpetual Wanjiku, Hosea Maroko, Nelson Kilimo
BackgroundFew studies have assessed the seroprevalence of antibodies against SARS-CoV-2 among Health Care Workers (HCWs) in Africa. We report findings from a survey among HCWs in three counties in Kenya.MethodsWe recruited 684 HCWs from Kilifi (rural
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa4c716864bb7254c3d7fa5372e1b2fa
https://doi.org/10.1101/2021.03.12.21253493
https://doi.org/10.1101/2021.03.12.21253493