Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Lucy A. Carver"'
Publikováno v:
BioTechniques, Vol 29, Iss 4, Pp 726-732 (2000)
Externí odkaz:
https://doaj.org/article/3330bfb60e694b8da0b1a67d72ac95c4
Autor:
Lucy A. Carver, Jan E. Schnitzer
Publikováno v:
Nature Reviews Cancer. 3:571-581
Caveolae exist at cell surfaces as caveolin-coated invaginations that perform transport and signalling functions influencing cell growth, apoptosis, angiogenesis and transvascular exchange. Caveolin could constitute a key switch in tumour development
Publikováno v:
Journal of Biological Chemistry. 269:30109-30112
In an effort to provide a more powerful system to study the Ah receptor (AHR) signaling pathway, we expressed the AHR, its dimerization partner ARNT, and a beta-galactosidase (lacZ) reporter gene, driven by two dioxin-responsive enhancers, in the yea
Publikováno v:
Cytogenetic and Genome Research. 66:172-176
The AHR locus encodes the structural gene for the Ah receptor, a ligand activated transcription factor that regulates the expression of a number of enzymes involved in the metabolism of chemical carcinogens and that appears to mediate the tumor promo
Autor:
Lucy A. Carver, Jan E. Schnitzer
Publikováno v:
Cancer Drug Discovery and Development ISBN: 9781588294258
The analytical power and throughput of current genomic and proteomic techniques is unparalleled in the history of medical research. Yet, directly and specifically targeting solid tumors in vivo remains a long-sought yet elusive goal of molecular medi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc2d455b5f4648145b673415a4a248d1
https://doi.org/10.1385/1-59259-893-5:151
https://doi.org/10.1385/1-59259-893-5:151
Publisher Summary Cellular membranes contain distinct micro-domains with unique molecular topographies, including caveolae and lipid rafts. Unlike caveolae, which form via protein–protein interactions, lipid rafts appear to form in the membrane whe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aed26e5b2d3805481386995babf9aa6c
https://doi.org/10.1016/b978-012164730-8/50074-5
https://doi.org/10.1016/b978-012164730-8/50074-5
Autor:
Jan E. Schnitzer, Lucy A. Carver, Karolina M. Krasinska, Phil Oh, Eberhard Durr, Jacqueline E Testa, Jingyi Yu, Yan Li
Publikováno v:
Nature. 429(6992)
The molecular complexity of tissues and the inaccessibility of most cells within a tissue limit the discovery of key targets for tissue-specific delivery of therapeutic and imaging agents in vivo. Here, we describe a hypothesis-driven, systems biolog
Autor:
Jingyi Yu, Eberhard Durr, Jacqueline E Testa, John R. Yates, Phil Oh, Karolina M. Krasinska, Jan E. Schnitzer, Lucy A. Carver
Publikováno v:
Nature biotechnology. 22(8)
Endothelial cells can function differently in vitro and in vivo; however, the degree of microenvironmental modulation in vivo remains unknown at the molecular level largely because of analytical limitations. We use multidimensional protein identifica