Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Lucy A. Bird"'
Autor:
Helen C. Bodmer, Maxime Breban, Lucy A. Bird, Cécile Hacquard-Bouder, Paul Bowness, Andrew J. McMichael, Hiromi Kubagawa, Matthew Roddis, Simon Kollnberger
HLA-B27 transgenic rats and strains of HLA-B27-transgenic β2-microglobulin (β2m)-deficient mice develop a multisystem inflammatory disease affecting the joints, skin, and bowel with strong similarity to human spondyloarthritis. We show that HLA-B27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3c3e65e739f273b2a47cdb6de84156a7
https://doi.org/10.4049/jimmunol.173.3.1699
https://doi.org/10.4049/jimmunol.173.3.1699
Publikováno v:
European journal of immunology. 33(3)
The MHC class I allele HLA-B27 is very strongly associated with development of autoimmune spondyloarthritis, although the disease mechanism remains unknown. Class I molecules classically associate in the endoplasmic reticulum (ER) with beta2-microglo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ec6f57c0f99ed1b39c08f52d8f9fd1ea
https://pubmed.ncbi.nlm.nih.gov/12616495
https://pubmed.ncbi.nlm.nih.gov/12616495
Autor:
Simon Kollnberger, Andrew J. McMichael, Mei-Yi Sun, Veronique M. Braud, Christelle Retière, Paul Bowness, Lucy A. Bird
Publikováno v:
Arthritis and rheumatism. 46(11)
OBJECTIVE: HLA-B27 is capable of forming in vitro a heavy-chain homodimer structure lacking beta(2)-microglobulin. We undertook this study to ascertain if patients with spondylarthritis express beta(2)-microglobulin-free HLA-B27 heavy chains in the f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cc04398b0182f0c66d7a4edd358ff13
https://pubmed.ncbi.nlm.nih.gov/12428240
https://pubmed.ncbi.nlm.nih.gov/12428240