Zobrazeno 1 - 10
of 407
pro vyhledávání: '"Lucy A Godley"'
Autor:
Qianxi Feng, Eric Nickels, Ivo S Muskens, Adam J de Smith, W James Gauderman, Amy C Yee, Charite Ricker, Thomas Mack, Andrew D Leavitt, Lucy A Godley, Joseph L Wiemels
Publikováno v:
eLife, Vol 10 (2021)
Background: The role of race/ethnicity in genetic predisposition of early-onset cancers can be estimated by comparing family-based cancer concordance rates among ethnic groups. Methods: We used linked California health registries to evaluate the rela
Externí odkaz:
https://doaj.org/article/eb9c360e1b36468e8eba790ad15f7171
Publikováno v:
OncoTargets and Therapy, Vol 2010, Iss default, Pp 1-13 (2010)
Jacqueline S Garcia1, Nitin Jain1, Lucy A Godley1,21Section of Hematology/Oncology, Department of Medicine, The University of Chicago, Chicago, IL, USA; 2Cancer Research Center, The University of Chicago, Chicago, IL, USAAbstract: Myelodysplastic syn
Externí odkaz:
https://doaj.org/article/51a3950e623747fe84f4c3b93331c9dd
DNMT3B7 expression promotes tumor progression to a more aggressive phenotype in breast cancer cells.
Autor:
Patrick R Brambert, Daniel J Kelpsch, Rabia Hameed, Charmi V Desai, Gianfranco Calafiore, Lucy A Godley, Stacey L Raimondi
Publikováno v:
PLoS ONE, Vol 10, Iss 1, p e0117310 (2015)
Epigenetic changes, such as DNA methylation, have been shown to promote breast cancer progression. However, the mechanism by which cancer cells acquire and maintain abnormal DNA methylation is not well understood. We have previously identified an abe
Externí odkaz:
https://doaj.org/article/6907d7fd857c4f47ba4e32f80fed7911
Autor:
Gregory W. Roloff, Satyajit Kosuri, Mariam T. Nawas, Adam S. DuVall, Anand A. Patel, Peter A. Riedell, Olatoyosi Odenike, Wendy Stock, Richard A. Larson, Michael R. Bishop, Emma Nunley, Lucy A. Godley, Feighanne Hathaway, Daniela del Gaudio, Soma Das, Lorraine E. Canham, Michael W. Drazer
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Not available.
Externí odkaz:
https://doaj.org/article/3109a98b0447457f96ddf0342244491f
Autor:
Qianxi Feng, Keren Xu, Mancy Shah, Shaobo Li, Andrew D. Leavitt, Lucy A. Godley, Adam J. de Smith, Joseph L. Wiemels
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Genetic predisposition to hematologic malignancies has historically been addressed utilizing patients recruited from clinical trials and pedigrees constructed at major treatment centers. Such efforts leave unexplored the genetic basis of variations i
Externí odkaz:
https://doaj.org/article/c44aecf7950842afa62ad47d9333a46d
Publikováno v:
JAAD Case Reports, Vol 37, Iss , Pp 119-122 (2023)
Externí odkaz:
https://doaj.org/article/7635fb0dbbd84b45a600851913790c9e
Autor:
Anastasia E. Hains, Sakshi Uppal, John Z. Cao, Helen R. Salwen, Mark A. Applebaum, Susan L. Cohn, Lucy A. Godley
Publikováno v:
Epigenetics, Vol 17, Iss 13, Pp 2056-2074 (2022)
Ten-Eleven-Translocation 5-methylcytosine dioxygenases 1–3 (TET1-3) convert 5-methylcytosine to 5-hydroxymethylcytosine (5-hmC), using oxygen as a co-substrate. Contrary to expectations, hypoxia induces 5-hmC gains in MYCN-amplified neuroblastoma (
Externí odkaz:
https://doaj.org/article/46684909df9349bab0c0b5b0bbd13c9a
Publikováno v:
Haematologica, Vol 109, Iss 1 (2023)
Externí odkaz:
https://doaj.org/article/3e3e41518c17474d97f82c3bdc1eb3a0
Autor:
Mabel Minji Jung, Siqi Shen, Giovanni A. Botten, Thomas Olender, Koichi R. Katsumura, Kirby D. Johnson, Alexandra A. Soukup, Peng Liu, Qingzhou Zhang, Zena D. Jensvold, Peter W. Lewis, Robert A. Beagrie, Jason K.K. Low, Lihua Yang, Joel P. Mackay, Lucy A. Godley, Marjorie Brand, Jian Xu, Sunduz Keles, Emery H. Bresnick
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 7 (2023)
Although certain human genetic variants are conspicuously loss of function, decoding the impact of many variants is challenging. Previously, we described a patient with leukemia predisposition syndrome (GATA2 deficiency) with a germline GATA2 variant
Externí odkaz:
https://doaj.org/article/0a1d39017eb14888912ea7fe69a08151
Autor:
Gregory W. Roloff, Frank Wen, Aubrianna Ramsland, Andrew S. Artz, Satyajit Kosuri, Wendy Stock, Olatoyosi Odenike, Richard A. Larson, Hongtao Liu, Lucy A. Godley, Michael J. Thirman, Anand A. Patel, Christopher K. Daugherty, Adam S. DuVall, Mariam T. Nawas, Emily Dworkin, Geoffrey D. Wool, Sandeep Gurbuxani, Carrie Fitzpatrick, Jeremy P. Segal, Peng Wang, Michael W. Drazer
Publikováno v:
Haematologica, Vol 108, Iss 8 (2023)
Externí odkaz:
https://doaj.org/article/1d4372d7237e4993adbe87d1b89ac577