Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Lucy A Bartho"'
Publikováno v:
Reproduction and Fertility, Vol 3, Iss 1, Pp 19-29 (2022)
Mitochondria are organelles within the cell that generate energy, which is essential to the developing placenta. As the placenta approaches term, organelles such as mitochondria and the endoplasmic reticulum adapt to cellular stressors (e.g. oxidativ
Externí odkaz:
https://doaj.org/article/9de10619d8994fb8ae8b1b434000ea8c
Autor:
Manju Kandel, Stephen Tong, Susan P Walker, Ping Cannon, Tuong-Vi Nguyen, Teresa M. MacDonald, Natalie J. Hannan, Tu’uhevaha J. Kaitu’u-Lino, Lucy A Bartho
Publikováno v:
Frontiers in Physiology, Vol 13 (2022)
Preeclampsia is a disease of pregnancy responsible for significant maternal and neonatal mortality. Galectin-3 is a β-Galactoside binding protein. This study aimed to characterise galectin-3 in women with preeclampsia and human trophoblast stem cell
Externí odkaz:
https://doaj.org/article/6ae85dac2026490296b52890bce0f9ab
Autor:
Lucy A. Bartho, Daniel R. McKeating, Susan P. Walker, Brunda Nijagal, Teresa M. MacDonald, Natasha Pritchard, Natalie J. Hannan, Anthony V. Perkins, Stephen Tong, Tu’uhevaha J. Kaitu’u-Lino
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Metabolomics is the study of small molecules (metabolites), within cells, tissues and biofluids. Maternal metabolites can provide important insight into the health and development of both mother and fetus throughout pregnancy. This study ass
Externí odkaz:
https://doaj.org/article/f38eb2cd176049bfb44b36cc0ecad250
Autor:
Lucy A Bartho, Manju Kandel, Susan P Walker, Catherine A Cluver, Roxanne Hastie, Lina Bergman, Natasha Pritchard, Ping Cannon, Tuong-Vi Nguyen, Georgia P Wong, Teresa M MacDonald, Emerson Keenan, Natalie J Hannan, Stephen Tong, Tu’uhevaha J Kaitu’u-Lino
Publikováno v:
Endocrinology. 164
Background: Preeclampsia is a severe complication of pregnancy. Chemerin is an adipokine secreted from adipose tissue and highly expressed in placenta. This study evaluated the biomarker potential of circulating chemerin to predict preeclampsia.Metho
Autor:
Tu'uhevaha J Kaitu'u-Lino, Jessica L. O’Callaghan, Anthony V. Perkins, Natalie J. Hannan, Vicki L. Clifton, Joshua J. Fisher, Lucy A. Bartho, James S. M. Cuffe
Publikováno v:
Placenta. 112:162-171
Introduction The human placenta has a defined lifespan and placental aging is a key feature as pregnancy progresses. Placental aging and mitochondrial dysfunction are known to play a key role in pregnancy pathophysiology. Premature aging of the place
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 319:E981-E994
Mitochondria play a key role in homeostasis and are central to one of the leading hypotheses of ageing, the free radical theory. Mitochondria function as a reticulated network, constantly adapting to the cellular environment through fusion (joining),
Autor:
Lucy A Bartho, Daniel R McKeating, Natalie J Hannan, Tu’uhevaha J Kaitu’u-Lino, Anthony V Perkins
Publikováno v:
Molecular human reproduction. 29(9)
As the placenta develops across gestation, the mitochondria and other organelles like the endoplasmic reticulum (ER) must continue to adapt to stressors such as oxidative stress. As pregnancy approaches term, these stressors may contribute to placent
Autor:
Lucy A. Bartho, James S. M. Cuffe, Daniel R. McKeating, Anthony V. Perkins, Joshua J. Fisher, Chelsea L. Vanderpeet, Olivia J. Holland
Publikováno v:
The Journal of Physiology. 599:1291-1305
Mitochondrial dysfunction is known to occur in diabetic phenotypes including type 1 and 2 diabetes mellitus. The incidence of Gestational diabetes mellitus (GDM) is increasing and defined as the onset of a diabetic phenotype during pregnancy. The rol
Publikováno v:
Reproductionfertility. 3(1)
Mitochondria are organelles within the cell that generate energy, which is essential to the developing placenta. As the placenta approaches term, organelles such as mitochondria and the endoplasmic reticulum adapt to cellular stressors (e.g. oxidativ
Autor:
Elliott S. Neal, Pierre Hofstee, Lucy A. Bartho, Anthony V. Perkins, James S. M. Cuffe, Montana R. Askew, Nykola L. Kent
Publikováno v:
Physiological Reports, Vol 9, Iss 6, Pp n/a-n/a (2021)
Physiological Reports
Physiological Reports
Selenium deficiency during pregnancy can impair fetal development and predispose offspring to thyroid dysfunction. Given that key selenoproteins are highly expressed in the kidney and that poor thyroid health can lead to kidney disease, it is likely