Zobrazeno 1 - 10
of 77
pro vyhledávání: '"Lucy A, Weinert"'
Autor:
Sophia K. Berry, Steven Rust, Lorraine Irving, Josefin Bartholdson Scott, Lucy A. Weinert, Gordon Dougan, Graham Christie, Paul Warrener, Ralph Minter, Andrew J. Grant
Publikováno v:
Microbiology Spectrum, Vol 12, Iss 8 (2024)
ABSTRACT We used phage display, antibody engineering, and high-throughput assays to identify antibody-accessible targets of Klebsiella pneumoniae. We report the discovery of monoclonal antibodies (mAbs) binding to type 3 fimbrial proteins, including
Externí odkaz:
https://doaj.org/article/95aa0fb605154b428c64e9bc9b28abc5
Autor:
Marta Matuszewska, Alicja Dabrowska, Gemma G. R. Murray, Steve M. Kett, Andy J. A. Vick, Sofie C. Banister, Leonardo Pantoja Munoz, Peter Cunningham, John J. Welch, Mark A. Holmes, Lucy A. Weinert
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Staphylococcus aureus is a human commensal and opportunistic pathogen that also infects other animals. In humans and livestock, where S. aureus is most studied, strains are specialized for different host species. Recent studies have also fou
Externí odkaz:
https://doaj.org/article/cb121dfb685040b9bc8e47b0e7df6d6f
Autor:
Sarah K Walsh, Ryan M Imrie, Marta Matuszewska, Gavin K Paterson, Lucy A Weinert, Jarrod D Hadfield, Angus Buckling, Ben Longdon
Publikováno v:
PLoS Pathogens, Vol 19, Iss 6, p e1011433 (2023)
Virus host shifts, where a virus transmits to and infects a novel host species, are a major source of emerging infectious disease. Genetic similarity between eukaryotic host species has been shown to be an important determinant of the outcome of viru
Externí odkaz:
https://doaj.org/article/e4e93718105f4b68b91199647a44aacf
Large-scale genomic analysis of antimicrobial resistance in the zoonotic pathogen Streptococcus suis
Autor:
Nazreen F. Hadjirin, Eric L. Miller, Gemma G. R. Murray, Phung L. K. Yen, Ho D. Phuc, Thomas M. Wileman, Juan Hernandez-Garcia, Susanna M. Williamson, Julian Parkhill, Duncan J. Maskell, Rui Zhou, Nahuel Fittipaldi, Marcelo Gottschalk, A. W. ( Dan) Tucker, Ngo Thi Hoa, John J. Welch, Lucy A. Weinert
Publikováno v:
BMC Biology, Vol 19, Iss 1, Pp 1-17 (2021)
Abstract Background Antimicrobial resistance (AMR) is among the gravest threats to human health and food security worldwide. The use of antimicrobials in livestock production can lead to emergence of AMR, which can have direct effects on humans throu
Externí odkaz:
https://doaj.org/article/7fc8e8f55e0f42288a6367456f0c33b2
Autor:
Marta Matuszewska, Gemma GR Murray, Xiaoliang Ba, Rhiannon Wood, Mark A Holmes, Lucy A Weinert
Publikováno v:
eLife, Vol 11 (2022)
Mobile genetic elements (MGEs) are agents of horizontal gene transfer in bacteria, but can also be vertically inherited by daughter cells. Establishing the dynamics that led to contemporary patterns of MGEs in bacterial genomes is central to predicti
Externí odkaz:
https://doaj.org/article/c88cc4f3d3bf47e89d14816021c3f261
Autor:
Samantha J. Hau, Shi-Lu Luan, Crystal L. Loving, Tracy L. Nicholson, Jinhong Wang, Sarah E. Peters, David Seilly, Lucy A. Weinert, Paul R. Langford, Andrew N. Rycroft, Brendan W. Wren, Duncan J. Maskell, Alexander W. Tucker, Susan L. Brockmeier, on behalf of the BRaDP1T Consortium
Publikováno v:
BMC Veterinary Research, Vol 16, Iss 1, Pp 1-9 (2020)
Abstract Background Glaesserella parasuis, the causative agent of Glӓsser’s disease, is widespread in swine globally resulting in significant economic losses to the swine industry. Prevention of Glӓsser’s disease in pigs has been plagued with a
Externí odkaz:
https://doaj.org/article/d70f84a628674d299961df7cbff7e6c4
Autor:
Gemma G. R. Murray, Andrew J. Balmer, Josephine Herbert, Nazreen F. Hadjirin, Caroline L. Kemp, Marta Matuszewska, Sebastian Bruchmann, A. S. Md. Mukarram Hossain, Marcelo Gottschalk, Alexander W. Tucker, Eric Miller, Lucy A. Weinert
Publikováno v:
PLoS Genetics, Vol 17, Iss 11 (2021)
Mutation rates vary both within and between bacterial species, and understanding what drives this variation is essential for understanding the evolutionary dynamics of bacterial populations. In this study, we investigate two factors that are predicte
Externí odkaz:
https://doaj.org/article/c33dbcb5f57e4a9bb55867d0f062883d
Autor:
Nusrat Nahar, Greg Tram, Freda E-C Jen, Zachary N Phillips, Lucy A Weinert, Janine T Bossé, Jafar S Jabbari, Quentin Gouil, Mei R M Du, Matthew E Ritchie, Rory Bowden, Paul R Langford, Alexander W Tucker, Michael P Jennings, Conny Turni, Patrick J Blackall, John M Atack
Publikováno v:
Nucleic Acids Research. 51:3240-3260
Actinobacillus pleuropneumoniae is the cause of porcine pleuropneumonia, a severe respiratory tract infection that is responsible for major economic losses to the swine industry. Many host-adapted bacterial pathogens encode systems known as phasevari
Autor:
Ruobing Wang, Lucy van Dorp, Liam P. Shaw, Phelim Bradley, Qi Wang, Xiaojuan Wang, Longyang Jin, Qing Zhang, Yuqing Liu, Adrien Rieux, Thamarai Dorai-Schneiders, Lucy Anne Weinert, Zamin Iqbal, Xavier Didelot, Hui Wang, Francois Balloux
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-9 (2018)
The recent plasmid-mediated spread of the mobilized colistin resistance gene mcr-1 poses a significant public health threat, requiring worldwide monitoring and surveillance. Here, Wang et al. compile and analyze a data set of 457 mcr-1-positive seque
Externí odkaz:
https://doaj.org/article/44dde83a6c0741f9a940b1f9d8f75e60
Autor:
Gemma G. R. Murray, A. S. Md. Mukarram Hossain, Eric Miller, Sebastian Bruchman, Andrew J. Balmer, Marta Matuszewska, Josephine Herbert, Nazreen F. Hadjirin, Robert Mugabi, Ganwu Li, Maria Laura Ferrando, Isabela Maria Fernandes de Oliveira, Thanh Nguyen, Phung L. K. Yen, Aung Zaw Moe, Thiri Su Wai, Marcelo Gottschalk, Virginia Aragon, Peter Valentin-Weigand, Peter M. H. Heegaard, Manouk Vrieling, Min Thein Maw, Hnin Thidar Myint, Ye Tun Win, Ngo Thi Hoa, Steven D. Bentley, Maria J. Clavijo, Jerry M. Wells, Alexander W. Tucker, Lucy A. Weinert
The expansion and intensification of livestock production is predicted to promote the emergence of pathogens. As pathogens sometimes jump between species this can affect the health of humans as well as livestock. Here we investigate how livestock mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b41872a7c28eb91627966b3cad8db81b
https://doi.org/10.1101/2023.05.17.540811
https://doi.org/10.1101/2023.05.17.540811