Zobrazeno 1 - 10
of 40
pro vyhledávání: '"Lucy, Rowell"'
Autor:
Sebastian H. Unizony, Bhaskar Dasgupta, Elena Fisheleva, Lucy Rowell, Georg Schett, Robert Spiera, Jochen Zwerina, Olivier Harari, John H. Stone
Publikováno v:
International Journal of Rheumatology, Vol 2013 (2013)
Overview. The GiACTA trial is a multicenter, randomized, double-blind, and placebo-controlled study designed to test the ability of tocilizumab (TCZ), an interleukin (IL)-6 receptor antagonist, to maintain disease remission in patients with giant cel
Externí odkaz:
https://doaj.org/article/9b80811afc9a48c9a37076d7816b9fb6
Autor:
Joy C. Hsu, Scott Fettner, Hisham Y. Abdallah, Gerd R Burmester, Alan Kivitz, Wendy Douglass, Xiaoping Zhang, Peng Lu, Lucy Rowell, Min Bao
Publikováno v:
The Journal of Clinical Pharmacology. 57:459-468
Tocilizumab is a humanized anti-interleukin-6 receptor antibody for treating rheumatoid arthritis. Pharmacokinetic/pharmacodynamic analysis was performed on the 24-week double-blind parts of 2 randomized, controlled trials: SUMMACTA and BREVACTA. SUM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b64c8fbbb4b48570589846772f176648
https://doi.org/10.1002/jcph.826
https://doi.org/10.1002/jcph.826
Autor:
Ladislav Timulak, James McElvaney, Jennifer Elaine Murphy, Rosie O'Flynn, Lucy Rowell, Anne McQuaid
Publikováno v:
Counselling and Psychotherapy Research. 17:56-70
Background Generalised anxiety disorder (GAD) is an anxiety disorder characterised by excessive anxiety and worry. Worry is seen as a key-defining feature of GAD. Several cognitive-behavioural models of working with worry in GAD exist. More recently,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5d8e2db445a3c9ad7963d87435a0880a
https://doi.org/10.1002/capr.12089
https://doi.org/10.1002/capr.12089
Autor:
Beatriz M Zazueta, Min Bao, Clare Nasmyth-Miller, Michael S. Borofsky, Lucy Rowell, Ewa Olech, Alan Kivitz, Sebastião Cezar Radominski, Janet E. Pope, Joan T. Merrill, Stephen Wright, Federico Navarro-Sarabia
Publikováno v:
Arthritis Care & Research
Objective The efficacy and safety of subcutaneous tocilizumab (TCZ-SC) versus subcutaneous placebo (PBO-SC) was evaluated in patients with rheumatoid arthritis who had an inadequate response to disease-modifying antirheumatic drugs in the BREVACTA st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c6de946bc3d57dba77b8f166d9cd187
https://doi.org/10.1002/acr.22384
https://doi.org/10.1002/acr.22384
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 52:27-38
Objectives: The objective of this study was to evaluate the effect of a single intravenous dose of tocilizumab (TCZ) on pharmacokinetics (PK) of oral contraceptive (OC; norethindrone (NE) and ethinyl estradiol (EE)) and on sex hormone levels (progest
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26751aade8410d8330fa7427dabad1ae
https://doi.org/10.5414/cp201951
https://doi.org/10.5414/cp201951
Autor:
Ya-Chi Chen, Tatiana Gott, Lucy Rowell, Scott Fettner, Paul Grimsey, Adam Unsworth, Xiaoping Zhang
Publikováno v:
Int. Journal of Clinical Pharmacology and Therapeutics. 51:620-630
Objectives: To investigate the pharmacokinetics, pharmacodynamics, safety and efficacy of subcutaneous tocilizumab 162 mg weekly (QW) or every other week (Q2W) in rheumatoid arthritis patients on methotrexate. Methods: This was a multicenter, open-la
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1e27c60df4b09614683ef6d4ce72b4d0
https://doi.org/10.5414/cp201904
https://doi.org/10.5414/cp201904
Autor:
Gerd R Burmester, Piotr Leszczyński, Charles Ludivico, Georgia Roane, Min Bao, Madura J. Rangaraj, Alain Cantagrel, Andrea Rubbert-Roth, Eduardo Mysler, Lucy Rowell, Peng Lu, Stephen B. Hall, Daniel Feldman
Publikováno v:
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Annals of the Rheumatic Diseases
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Annals of the Rheumatic Diseases
Roche. F. Hoffmann-La Roche, Ltd (Roche) Objectives This study compared the efficacy and safety of subcutaneous (SC) versus intravenous (IV) formulations of tocilizumab in patients with rheumatoid arthritis with an inadequate response to disease-modi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::041ef20aa8431709510830efd2cccfb3
https://doi.org/10.1136/annrheumdis-2013-203523
https://doi.org/10.1136/annrheumdis-2013-203523
Autor:
Richard A. Robson, Judith Anzures-Cabrera, Gerhard Arold, Olaf Kuhlmann, David Carlile, Lucy Rowell, Mary Phelan, Darren Bentley
Publikováno v:
Clinical Pharmacokinetics. 52:255-265
Dalcetrapib, a cholesteryl ester transfer protein (CETP) modulator, is a thioester pro-drug that is rapidly hydrolysed to generate a pharmacologically active thiol. The thiol covalently binds to plasma proteins as mixed disulfides, extensively distri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6358eb53b0acf872fe1b28b40b4061cb
https://doi.org/10.1007/s40262-013-0035-z
https://doi.org/10.1007/s40262-013-0035-z
Autor:
Jochen Zwerina, Olivier Harari, Lucy Rowell, Robert Spiera, Bhaskar Dasgupta, Sebastian Unizony, John H. Stone, Georg Schett, Elena Fisheleva
Publikováno v:
International Journal of Rheumatology
International Journal of Rheumatology, Vol 2013 (2013)
International Journal of Rheumatology, Vol 2013 (2013)
Overview. The GiACTA trial is a multicenter, randomized, double-blind, and placebo-controlled study designed to test the ability of tocilizumab (TCZ), an interleukin (IL)-6 receptor antagonist, to maintain disease remission in patients with giant cel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba897214ac1aa71dd296942964b8bf37
https://doi.org/10.1155/2013/912562
https://doi.org/10.1155/2013/912562
Autor:
Madura J. Rangaraj, Charles Ludivico, Georgia Roane, Daniel Feldman, Lucy Rowell, Piotr Leszczyński, Andrea Rubbert-Roth, Stephen B. Hall, Min Bao, Eduardo Mysler, Gerd R Burmester, Alain Cantagrel, Claire Davies
Publikováno v:
Repositório Institucional da UNIFESP
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Annals of the Rheumatic Diseases
Universidade Federal de São Paulo (UNIFESP)
instacron:UNIFESP
Annals of the Rheumatic Diseases
Roche F. Hoffmann-La Roche, Ltd. Objectives To evaluate the long-term efficacy and safety of subcutaneous (SC) tocilizumab (TCZ) versus intravenous (IV) TCZ, including switching formulations, in patients with rheumatoid arthritis (RA) and inadequate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9656a693216da8c7d42d3e0c5c34044c
http://repositorio.unifesp.br/handle/11600/49698
http://repositorio.unifesp.br/handle/11600/49698
