Výsledky vyhledávání - "Lucio Tentori"

Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab

Autor: Grazia, Graziani, Lucia, Lisi, Lucio, Tentori, Pierluigi, Navarra

Publikováno v: Experientia supplementum (2012). 113

The immune checkpoint cytotoxic T lymphocyte-associated antigen 4 (CTLA-4 or CD152) is a negative regulator of T-cell-mediated immune responses which plays a critical role in suppressing autoimmunity and maintaining immune homeostasis. Because of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::218f4caea6091d2f2fadcd9807e63c93
https://pubmed.ncbi.nlm.nih.gov/35165868

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Monoclonal Antibodies to CTLA-4 with Focus on Ipilimumab

Autor: Grazia Graziani, Lucia Lisi, Lucio Tentori, Pierluigi Navarra

Publikováno v: Experientia Supplementum ISBN: 9783030913106

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::45a6741b2dfe96ab1217a31679c721e4
https://doi.org/10.1007/978-3-030-91311-3_10

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Targeting the vascular endothelial growth factor receptor-1 by the monoclonal antibody D16F7 to increase the activity of immune checkpoint inhibitors against cutaneous melanoma

Autor: Rosella Cicconi, Grazia Graziani, Manuel Scimeca, Roberta Bernardini, Pedro Miguel Lacal, Lucio Tentori, Elena Bonanno, Maria Grazia Atzori, Federica Ruffini, Stefania D'Atri, Maurizio Mattei

The vascular endothelial growth factor receptor-1 (VEGFR-1) is a membrane receptor for VEGF-A, placenta growth factor (PlGF) and VEGF-B that plays a crucial role in melanoma invasiveness, vasculogenic mimicry and tumor-associated angiogenesis. Furthe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4655779bd12726d979a3f7c3d816ee3b
http://hdl.handle.net/2108/256590

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Modulation of GDF11 expression and synaptic plasticity by age and training

Autor: Paola Grimaldi, Grazia Graziani, Giovanna D'Arcangelo, Emanuela De Domenico, Lucio Tentori, Mattia Palmieri, Isabella Faraoni, Virginia Tancredi

Publikováno v: Oncotarget

The Growth Differentiation Factor 11 (GDF11) has been controversially involved in the aging/rejuvenation process. To clarify whether GDF11 is differently expressed during aging, we have evaluated GDF11 levels in skeletal muscles and hippocampi of you

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba5fc6be3fdb79ba6c98c5501f7b7e0a
https://doi.org/10.18632/oncotarget.19854

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Role of VEGFR-1 in melanoma acquired resistance to the BRAF inhibitor vemurafenib

Autor: Claudia Ceci, Maria Luisa Barbaccia, Pedro Miguel Lacal, Maria Grazia Atzori, Stefania D'Atri, Mauro Trapani, Grazia Graziani, Lucio Tentori, Federica Ruffini

Publikováno v: Journal of Cellular and Molecular Medicine

The vascular endothelial growth factor receptor‐1 (VEGFR‐1) is a tyrosine kinase receptor frequently expressed in melanoma. Its activation by VEGF‐A or placental growth factor (PlGF) promotes tumour cell survival, migration and invasiveness. Mo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::78649ca9a820f706b95e9d946e535ca5
https://pubmed.ncbi.nlm.nih.gov/31758648

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Effects of Glutathione Transferase-Targeting Nitrobenzoxadiazole Compounds in Relation to PD-L1 Status in Human Melanoma Cells

Autor: Camilla Palumbo, Lucio Tentori, Dante Rotili, Grazia Graziani, Chiara Fulci, Francesca Sciarretta, Anna Maria Caccuri

Background: PD-L1 is a membrane protein with inhibitory effects on immune responses, whose expression has been correlated with high aggressiveness and the propensity of melanoma to metastasize. The nitrobenzoxadiazole (NBD) NBDHEX and its analog MC31

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9814527f190d25b6da9b68b8f7aa0e8f
http://hdl.handle.net/2108/224878

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Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding

Autor: Pedro Miguel Lacal, Stefania D'Atri, Veronica Morea, Cristina Maria Failla, Elena Bonanno, Manuel Scimeca, Grazia Graziani, Federica Ruffini, Maria Grazia Atzori, Annalisa Susanna Dorio, Lucio Tentori

Publikováno v: Oncotarget
Oncotarget 7 (2016): 72868–72885. doi:10.18632/oncotarget.12108
info:cnr-pdr/source/autori:Graziani, Grazia; Ruffini, Federica; Tentori, Lucio; Scimeca, Manuel; Dorio, Annalisa S.; Atzori, Maria Grazia; Failla, Cristina M.; Morea, Veronica; Bonanno, Elena; D'Atri, Stefania; Lacal, Pedro M./titolo:Antitumor activity of a novel anti-vascular endothelial growth factor receptor-1 monoclonal antibody that does not interfere with ligand binding/doi:10.18632%2Foncotarget.12108/rivista:Oncotarget/anno:2016/pagina_da:72868/pagina_a:72885/intervallo_pagine:72868–72885/volume:7

Vascular endothelial growth factor receptor-1 (VEGFR-1) is a tyrosine kinase transmembrane receptor that has also a soluble isoform containing most of the extracellular ligand binding domain (sVEGFR-1). VEGF-A binds to both VEGFR-2 and VEGFR-1, where

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::210f302d2289624dc64e51cfac7bb5ca
https://doi.org/10.18632/oncotarget.12108

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Experimental Evidence of the Antitumor, Antimetastatic and Antiangiogenic Activity of Ellagic Acid

Autor: Roberto Miano, Grazia Graziani, Pedro Miguel Lacal, Maria Gabriella De Martino, Lucio Tentori, Claudia Ceci

Publikováno v: Nutrients
Nutrients, Vol 10, Iss 11, p 1756 (2018)

Ellagic acid (EA) is a naturally occurring polyphenolic compound endowed with strong antioxidant and anticancer properties that is present in high quantity in a variety of berries, pomegranates, and dried fruits. The antitumor activity of EA has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea49262ef9e61b5de515c5e1111c3168
https://pubmed.ncbi.nlm.nih.gov/30441769

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