Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Lucinda Puebla-Clark"'
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In recent years, porcine dendritic cells (DCs) have been identified from pig tissues. However, studying the interaction of porcine DCs with pathogens is still difficult due to the scarcity of DCs in tissues. In the present work, the Flt3-ligand (Flt3
Externí odkaz:
https://doaj.org/article/c90cc418ec354a66b1b0eb6e0f9141ca
Autor:
Victor H. Carpio, Florentin Aussenac, Lucinda Puebla-Clark, Kyle D. Wilson, Alejandro V. Villarino, Alexander L. Dent, Robin Stephens
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101310- (2020)
Summary: Hybrid Th1/Tfh cells (IFN-γ+IL-21+CXCR5+) predominate in response to several persistent infections. In Plasmodium chabaudi infection, IFN-γ+ T cells control parasitemia, whereas antibody and IL-21+Bcl6+ T cells effect final clearance, sugg
Externí odkaz:
https://doaj.org/article/b487e74dccc04a409f18f5c68412ec2a
Autor:
Maricela Montalvo Corral, Lucinda Puebla Clark, Guadalupe López Robles, Itzel Reyes Duarte, Guillermo López Cervantes, Silvia Y. Moya Camarena
Publikováno v:
Nova Scientia, Vol 10, Iss 21, Pp 228-246 (2019)
Introducción Giardia lamblia es un parásito intestinal de prevalencia mundial. Es capaz de evadir los mecanismos de defensa del hospedero. Las células presentadoras de antígeno (CPA), como las células dendríticas y macrófagos, orquestan la res
Externí odkaz:
https://doaj.org/article/8285a3c03a2a4d1ba1c6a3e390e82e07
Autor:
Maricela Montalvo Corral, Lucinda Puebla Clark, Guadalupe López Robles, Itzel Reyes Duarte, Guillermo López Cervantes, Silvia Yolanda Moya Camarena
Publikováno v:
Nova Scientia, Vol 10, Iss 21 (2018)
Introduction: Giardia lamblia, a protozoan intestinal parasite is able to evade or suppress defense mechanisms, such as innate response. Antigen presenting cells (APC) like dendritic cells may orchestrate an immune response and support a more effecti
Externí odkaz:
https://doaj.org/article/e596c783a639429c912e8ce48ef5ebea
Autor:
Maria J Gonzalez Orozco, Adam Hage, Hongjie Xia, Matthew Huante, Sarah van Tol, Maria I Giraldo, Lucinda Puebla-Clark, Vineet Menachery, Robin Stephens, Mark Endsley, Janice Endsley, Pei-Yong Shi, Alexander Freiberg, Ricardo Rajsbaum
Publikováno v:
The Journal of Immunology. 208:51.07-51.07
Cytokines, such as type-I Interferons (IFN-I), are essential to mount an effective antiviral response. The production of IFN-I is regulated by multiple mechanisms, including ubiquitination of host signaling factors. However, viruses can hijack the ub
Publikováno v:
The Journal of Immunology. 208:170.33-170.33
Germinal center (GC) formation in P. chabaudi rodent malaria is delayed for three weeks, which can prolong the infection. T follicular helper (Tfh) cells express CXCR5 for homing to the B cell area, and IL-21 which promotes antibody production. T hel
Autor:
Kyle D. Wilson, Alejandro V. Villarino, Florentin Aussenac, Alexander L. Dent, Robin Stephens, Victor H. Carpio, Lucinda Puebla-Clark
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101310-(2020)
iScience
iScience
Summary Hybrid Th1/Tfh cells (IFN-γ+IL-21+CXCR5+) predominate in response to several persistent infections. In Plasmodium chabaudi infection, IFN-γ+ T cells control parasitemia, whereas antibody and IL-21+Bcl6+ T cells effect final clearance, sugge
Autor:
Olivia Valenzuela, Héctor Parra-Sánchez, Jesús Hernández, Mónica Reséndiz, Lucinda Puebla-Clark
Publikováno v:
Molecular Immunology
Highlights • This study describes the characterization of cDCs, cDC1 and cDC2 in porcine lymphoid tissues. • Results show that the spleen had the highest frequency of cDCs. • The cDC1:cDC2 ratio showed a predominant presence of cDC1 in all lymp
Autor:
Robin Stephens, Florentin Aussenac, Lucinda Puebla Clark, Kyle D. Wilson, Alexander L. Dent, Victor H. Carpio
Publikováno v:
The Journal of Immunology. 204:75.8-75.8
Hybrid Th1/Tfh cells (IFN-γ+IL-21+CXCR5+) predominate in response to persistent infections. However, it is not clear if the function of these cells is plastic and might be modulated. In infection with Plasmodium spp, an IFN-γ+ T helper-1 (Th1) resp
Autor:
Héctor Parra-Sánchez, Mónica Reséndiz, Lucinda Puebla-Clark, Olivia Valenzuela, Jesús Hernández
Publikováno v:
Virology. 529
Porcine reproductive and respiratory syndrome virus (PRRSV) infects monocyte-derived DCs, and previous reports have shown that PRRSV does not infect conventional DCs (cDCs) in vitro, but the effects on cDCs from lymphoid tissues are unknown. This stu