Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Lucinda K Southworth"'
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000776 (2009)
In this work we present a method for the differential analysis of gene co-expression networks and apply this method to look for large-scale transcriptional changes in aging. We derived synonymous gene co-expression networks from AGEMAP expression dat
Externí odkaz:
https://doaj.org/article/e11d35b5b5ec4ebd8cb2fffdd642e2c9
Autor:
Jinkuk Choi, Lucinda K Southworth, Kavita Y Sarin, Andrew S Venteicher, Wenxiu Ma, Woody Chang, Peggie Cheung, Sohee Jun, Maja K Artandi, Naman Shah, Stuart K Kim, Steven E Artandi
Publikováno v:
PLoS Genetics, Vol 4, Iss 1, p e10 (2008)
Telomerase serves a critical role in stem cell function and tissue homeostasis. This role depends on its ability to synthesize telomere repeats in a manner dependent on the reverse transcriptase (RT) function of its protein component telomerase RT (T
Externí odkaz:
https://doaj.org/article/c7704b6f7fe240faae29230b2e83f500
Autor:
Yelena V. Budovskaya, Min Jiang, Thomas E. Johnson, Kendall Wu, Lucinda K. Southworth, Stuart K. Kim, Patricia M. Tedesco
Publikováno v:
Cell. 134:291-303
SummaryTo define the C. elegans aging process at the molecular level, we used DNA microarray experiments to identify a set of 1294 age-regulated genes and found that the GATA transcription factors ELT-3, ELT-5, and ELT-6 are responsible for age regul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::64f776e55efb57c6985ca2ebb140227b
https://doi.org/10.1016/j.cell.2008.05.044
https://doi.org/10.1016/j.cell.2008.05.044
Publikováno v:
Journal of computational biology : a journal of computational molecular cell biology. 16(4)
This paper takes a close look at balanced permutations, a recently developed sample reuse method with applications in bioinformatics. It turns out that balanced permutation reference distributions do not have the correct null behavior, which can be t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e23d36d0e9936420854db140648ff5
https://pubmed.ncbi.nlm.nih.gov/19361331
https://pubmed.ncbi.nlm.nih.gov/19361331
Publikováno v:
PLoS Genetics, Vol 5, Iss 12, p e1000776 (2009)
PLoS Genetics
PLoS Genetics
In this work we present a method for the differential analysis of gene co-expression networks and apply this method to look for large-scale transcriptional changes in aging. We derived synonymous gene co-expression networks from AGEMAP expression dat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ef8d20f22a8fc773eec5330a5c7037e
https://doi.org/10.1371/journal.pgen.1000776
https://doi.org/10.1371/journal.pgen.1000776
Autor:
Woody Chang, Maja Artandi, Lucinda K. Southworth, Kavita Y. Sarin, Naman Shah, Steven E. Artandi, Andrew S. Venteicher, Wenxiu Ma, Sohee Jun, Peggie Cheung, Jinkuk Choi, Stuart K. Kim
Publikováno v:
PLoS Genetics, Vol 4, Iss 1, p e10 (2008)
PLoS Genetics
PLoS Genetics
Telomerase serves a critical role in stem cell function and tissue homeostasis. This role depends on its ability to synthesize telomere repeats in a manner dependent on the reverse transcriptase (RT) function of its protein component telomerase RT (T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a82bf36bec7d811980ddb0ac8d2516b4
https://doi.org/10.1371/journal.pgen.0040010.eor
https://doi.org/10.1371/journal.pgen.0040010.eor