Supplementary Table S2: A hypothetical example of an updated DTP for Cohorts 4 to 6 in the Viola trial from Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

Autor: John O'Quigley, Charlie Craddock, Ying Kuen Cheung, Lucinda J. Billingham, Christina Yap

A hypothetical example of an updated DTP for Cohorts 4 to 6 in the Viola trial after observing 0/3 DLT at Dose 0, 1/3 DLT at Dose 1 and 0/3 DLT at Dose 1 for Cohorts 1 to 3 respectively (i.e. pathway 5 in Table 2). This table presents all 64 pathways

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d6a311f1fba250c7dbe3ed61b3a83b0
https://doi.org/10.1158/1078-0432.22461983.v1

Data from Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

Autor: John O'Quigley, Charlie Craddock, Ying Kuen Cheung, Lucinda J. Billingham, Christina Yap

The ever-increasing pace of development of novel therapies mandates efficient methodologies for assessment of their tolerability and activity. Evidence increasingly support the merits of model-based dose-finding designs in identifying the recommended

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a2208128856dc3c1e06195cb93755bf
https://doi.org/10.1158/1078-0432.c.6524975.v1

Supplementary Table S3: A hypothetical example of an updated DTP for Cohorts 7 to 9 in the Viola trial from Dose Transition Pathways: The Missing Link Between Complex Dose-Finding Designs and Simple Decision-Making

Autor: John O'Quigley, Charlie Craddock, Ying Kuen Cheung, Lucinda J. Billingham, Christina Yap

A hypothetical example of an updated DTP for Cohorts 7 to 9 in the Viola trial with the final recommended MTD. This is based on observing DLT outcomes of 0/3 DLT at Dose 0, 1/3 DLT at Dose 1 and 0/3 DLT at Dose 1 for Cohorts 1 to 3 respectively (path

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::598d255369c85839fe17d38eb0557e40
https://doi.org/10.1158/1078-0432.22461980.v1

Excision repair cross-complementation group 1 (ERCC1) status and lung cancer outcomes: a meta-analysis of published studies and recommendations.

Autor: Richard A Hubner, Richard D Riley, Lucinda J Billingham, Sanjay Popat

Publikováno v: PLoS ONE, Vol 6, Iss 10, p e25164 (2011)

PurposeDespite discrepant results on clinical utility, several trials are already prospectively randomizing non-small cell lung cancer (NSCLC) patients by ERCC1 status. We aimed to characterize the prognostic and predictive effect of ERCC1 by systema

Externí odkaz: https://doaj.org/article/6d23c15f72c544d1ba6ec3553e94e073

Contributors

Autor: Alex A. Adjei, Mjung-Ju Ahn, Chris I. Amos, Alberto Antonicelli, Hisao Asamura, Todd Atwood, Paul Baas, Joan E. Bailey-Wilson, David Ball, Fabrice Barlesi, Jose G. Bazan, José Belderbos, Andrea Bezjak, Lucinda J. Billingham, Paolo Boffetta, Martina Bonifazi, Julie R. Brahmer, Elisabeth Brambilla, Fraser Brims, Alessandro Brunelli, Ayesha Bryant, Nicholas Campbell, Brett W. Carter, Robert Cerfolio, Byoung Chul Cho, William C.S. Cho, Hak Choy, Chia-Yu Chu, Glenda Colburn, Henri Colt, Rafael Rosell Costa, Gail E. Darling, Mellar Davis, Patricia M. de Groot, Harry J. de Koning, Paul De Leyn, Dirk De Ruysscher, Ayşe Nur Demiral, Jules Derks, Frank C. Detterbeck, Siddhartha Devarakonda, Anne-Marie C. Dingemans, Jessica S. Donington, Carolyn M. Dresler, Steven M. Dubinett, Grace K. Dy, Jeremy J. Erasmus, Alysa Fairchild, Dean A. Fennell, Hiran C. Fernando, Pier Luigi Filosso, Raja Flores, Kwun Fong, Jesme Fox, David R. Gandara, Leena Gandhi, Laurie Gaspar, Stefano Gasparini, Adi F. Gazdar, Giuseppe Giaccone, Nicolas Girard, Peter Goldstraw, Elizabeth M. Gore, Glenwood Goss, Ramaswamy Govindan, Alissa K. Greenberg, Dominique Grunenwald, Matthias Guckenberger, Swati Gulati, Raffit Hassan, Christopher Hazzard, Fiona Hegi, Thomas Hensing, Roy Herbst, Fred R. Hirsch, Nanda Horeweg, David M. Jablons, James R. Jett, Andrew Kaufman, Paul Keall, Karen Kelly, Feng-Ming (Spring) Kong, Kaoru Kubota, Ite A. Laird-Offringa, Primo N. Lara, Janessa Laskin, Quynh-Thu Le, Cécile Le Péchoux, Elvira L. Liclican, Yolande Lievens, Chia-Chi (Josh) Lin, Billy W. Loo, Michael Mac Manus, Homer A. Macapinlac, Fergus Macbeth, William J. Mackillop, Christopher Maher, Isa Mambetsariev, Sumithra J. Mandrekar, Aaron S. Mansfield, Lawrence B. Marks, Céline Mascaux, Pierre P. Massion, Julien Mazieres, Annette McWilliams, Tetsuya Mitsudomi, Tony Mok, Daniel Morgensztern, Francoise Mornex, James L. Mulshine, Reginald F. Munden, Kristiaan Nackaerts, Shinji Nakamichi, Masayuki Noguchi, Krista Noonan, Silvia Novello, Anna K. Nowak, Kenneth J. O’Byrne, Nisha Ohri, Morihito Okada, Jamie S. Ostroff, Mamta Parikh, Elyse R. Park, Keunchil Park, Harvey I. Pass, Nicholas Pastis, Luis Paz-Ares, Nathan Pennell, Maurice Perol, Rathi N. Pillai, Pieter E. Postmus, Suresh S. Ramalingham, Sara Ramella, Ramón Rami-Porta, Martin Reck, Mary W. Redman, Niels Reinmuth, Umberto Ricardi, David Rice, Carole A. Ridge, William N. Rom, Kenneth E. Rosenzweig, Enrico Ruffini, Valerie W. Rusch, Ravi Salgia, Montse Sanchez-Cespedes, Anjali Saqi, Giorgio V. Scagliotti, Selma Schimmel, Ann G. Schwartz, Suresh Senan, Francis A. Shepherd, Jill M. Siegfried, Gerard A. Silvestri, George R. Simon, Egbert F. Smit, Stephen B. Solomon, Laura P. Stabile, Matthew A. Steliga, Thomas E. Stinchcombe, Nicholas S. Stollenwerk, Jong-Mu Sun, Anish Thomas, Ming-Sound Tsao, Jun-Chieh J. Tsay, Paul Van Houtte, Paul E. Van Schil, Nico van Zandwijk, J.F. Vansteenkiste, Marileila Varella-Garcia, Giulia Veronesi, Shalini K. Vinod, Everett E. Vokes, Heather Wakelee, Tonya C. Walser, Shun-ichi Watanabe, Walter Weder, Benjamin Wei, Ignacio I. Wistuba, James Chih-Hsin Yang, David F. Yankelevitz, Kazuhiro Yasufuku, Ken Y. Yoneda, Gérard Zalcman, Caicun Zhou, Yang Zhou, Daniel Zips

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::76bdf7bb6ef73b271ecb1e7f91a917b6
https://doi.org/10.1016/b978-0-323-52357-8.01002-7