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of 13
pro vyhledávání: '"Lucinda A. Grande"'
Autor:
Lucinda A. Grande, Tom Hutch, Keira Jack, Wendy Mironov, Jessica Iwuoha, Martin Muy-Rivera, Jacob Grillo, Stephen A. Martin, Andrew Herring
Publikováno v:
Addiction Science & Clinical Practice, Vol 19, Iss 1, Pp 1-11 (2024)
Abstract Background Many people with opioid use disorder who stand to benefit from buprenorphine treatment are unwilling to initiate it due to experience with or fear of both spontaneous and buprenorphine-precipitated opioid withdrawal (BPOW). An eff
Externí odkaz:
https://doaj.org/article/a0b9a2d2f9374959a4aea7b7d43c12f0
Autor:
Lucinda A. Grande
Publikováno v:
Journal of Addiction Medicine. 16:4-6
Buprenorphine-naloxone (BNX) reduces the risk of mortality from untreated opioid use disorder by 50% or more. However, adverse effects of BNX can be a cause of inconsistent use or discontinuation. The buprenorphine monoproduct (BUP) is effective and
Autor:
Devin Sawyer, Laura-Mae Baldwin, Lucinda A. Grande, Ellen Campbell Thompson, Roger A. Rosenblatt, Margaret A. Au
Publikováno v:
Journal of the American Board of Family Medicine : JABFM. 29(6)
Purpose: Problem drug-related behavior (PDB) among patients on chronic opioid therapy may reflect an opioid use disorder. This study assessed PDB prevalence and the relationship between PDB and ongoing prescription of opioids at a primary care clinic
Publikováno v:
Anesthesia & Analgesia. 107:1380-1383
Patients taking high-dose opioids chronically for tumor-related or neuropathic pain may develop pain that is refractory to opioids. One option for control of such pain is the use of the N-methyl-D-aspartate (NMDA) receptor antagonist ketamine. We des
Publikováno v:
The Journal of Neuroscience. 19:10153-10163
To assess behavioral experience effects on synaptic plasticity after brain damage, the present study examined the effects of complex motor skills training (the acrobatic task) on synaptic changes in layer V of the motor cortex opposite unilateral dam
Autor:
William J. Spain, Lucinda A. Grande
Publikováno v:
Physiology (Bethesda, Md.). 20
A depressing synapse transforms a time interval into a voltage amplitude. The effect of that transformation on the output of the neuron and network depends on the kinetics of synaptic depression and properties of the postsynaptic neuron and network.
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 24(8)
The firing rate of neocortical pyramidal neurons is believed to represent primarily the average arrival rate of synaptic inputs; however, it has also been found to vary somewhat depending on the degree of synchrony among synaptic inputs. We investiga
Publikováno v:
Pain. 110(1-2)
A man in his 50's with a prior traumatic brain injury and multiple psychiatric disorders developed acute pain and swelling in his left leg distal to the mid shin. These symptoms arose during an exacerbation of his post-traumatic stress disorder (PTSD
Publikováno v:
Nature. 421(6918)
Short-term synaptic plasticity, which is common in the central nervous system, may contribute to the signal processing functions of both temporal integration and coincidence detection. For temporal integrators, whose output firng rate depends on a ru
Publikováno v:
The Lancet. 373:1222