Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lucinda, Tam"'
Autor:
Arivazhagan Sambandam, Elaine Storm, Helen Tauc, Jason A. Hackney, David Garfield, Patrick Caplazi, John Liu, Juan Zhang, Hua Zhang, Jeff Duggan, Surinder Jeet, Sarah Gierke, Patrick Chang, Xiumin Wu, Robert Newman, Lucinda Tam, Tuija Alcantar, Lifen Wang, Meron Roose-Girma, Zora Modrusan, Wyne P. Lee, Heinrich Jasper, Frederic de Sauvage, Rajita Pappu
Publikováno v:
Heliyon, Vol 9, Iss 3, Pp e14238- (2023)
The ability of stem cells to rapidly proliferate and differentiate is integral to the steady-state maintenance of tissues with high turnover such as the blood and intestine. Mutations that alter these processes can cause primary immunodeficiencies, m
Externí odkaz:
https://doaj.org/article/5f0b411f56a24ccdae5dfc7e215eea4e
Autor:
Hsiao-Yen Ma, Elsa-Noah N’Diaye, Patrick Caplazi, Zhiyu Huang, Alexander Arlantico, Surinder Jeet, Aaron Wong, Hans D. Brightbill, Qingling Li, Weng Ruth Wong, Wendy Sandoval, Lucinda Tam, Robert Newman, Merone Roose-Girma, Ning Ding
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-11 (2022)
Abstract Bone morphogenetic protein 1 (BMP1) belongs to the astacin/BMP1/tolloid-like family of zinc metalloproteinases, which play a fundamental role in the development and formation of extracellular matrix (ECM). BMP1 mediates the cleavage of carbo
Externí odkaz:
https://doaj.org/article/e0c353ad1e8e4c3a9db3aafe0b1e52bb
Autor:
Kate Senger, Wenlin Yuan, Meredith Sagolla, Jonas Doerr, Brad Bolon, James Ziai, Kai‐Hui Sun, Soren Warming, Merone Roose‐Girma, Na Zhang, Lucinda Tam, Robert J. Newman, Subhra Chaudhuri, Aju Antony, Leonard D. Goldstein, Steffen Durinck, Bijay S. Jaiswal, Daniel Lafkas, Zora Modrusan, Somasekar Seshagiri
Publikováno v:
Advanced Genetics, Vol 2, Iss 1, Pp n/a-n/a (2021)
Abstract ERBB3 is a pseudokinase domain‐containing member of the ERBB family of receptor tyrosine kinases (RTKs). Following ligand binding, ERBB receptors homo‐ or hetero‐dimerize, leading to a head‐to‐tail arrangement of the intracellular
Externí odkaz:
https://doaj.org/article/e07cd0add97d47c6835d733394de07a7
Autor:
Akshay T. Krishnamurty, Justin A. Shyer, Minh Thai, Vineela Gandham, Matthew B. Buechler, Yeqing Angela Yang, Rachana N. Pradhan, Amber W. Wang, Patricia L. Sanchez, Yan Qu, Beatrice Breart, Cécile Chalouni, Debra Dunlap, James Ziai, Justin Elstrott, Neelie Zacharias, Weiguang Mao, Rebecca K. Rowntree, Jack Sadowsky, Gail D. Lewis, Thomas H. Pillow, Barzin Y. Nabet, Romain Banchereau, Lucinda Tam, Roger Caothien, Natasha Bacarro, Merone Roose-Girma, Zora Modrusan, Sanjeev Mariathasan, Sören Müller, Shannon J. Turley
Publikováno v:
Nature. 611:148-154
Recent single-cell studies of cancer in both mice and humans have identified the emergence of a myofibroblast population specifically marked by the highly restricted leucine-rich-repeat-containing protein 15 (LRRC15)1–3. However, the molecular sign
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1180240064ddca96a7dbfb51299c508a
https://doi.org/10.1038/s41586-022-05272-1
https://doi.org/10.1038/s41586-022-05272-1
Autor:
Katherine Bao, Juan Zhang, Alexis Scherl, James Ziai, Azi Hadadianpour, Daqi Xu, Christopher Dela Cruz, John Liu, Yuxin Liang, Lucinda Tam, Cesar A. Corzo, Merone Roose-Girma, Soren Warming, Zora Modrusan, Wyne P. Lee, Kam Hon Hoi, Ali A. Zarrin
Publikováno v:
The Journal of Immunology. 208:2632-2642
Genetic and environmental cues shape the evolution of the B cell Ig repertoire. Activation-induced cytidine deaminase (AID) is essential to generating Ig diversity through isotype class switching and somatic mutations, which then directly influence c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c7df2e88b7d04fa4a050bba87261356c
https://doi.org/10.4049/jimmunol.2101193
https://doi.org/10.4049/jimmunol.2101193
Autor:
Hsiao-Yen Ma, Qingling Li, Weng Ruh Wong, Elsa-Noah N’Diaye, Patrick Caplazi, Hannah Bender, Zhiyu Huang, Alexander Arlantico, Surinder Jeet, Aaron Wong, Claire Emson, Hans Brightbill, Lucinda Tam, Robert Newman, Merone Roose-Girma, Wendy Sandoval, Ning Ding
Publikováno v:
Science Advances. 9
Idiopathic pulmonary fibrosis is a progressive fibrotic disease characterized by excessive deposition of (myo)fibroblast produced collagen fibrils in alveolar areas of the lung. Lysyl oxidases (LOXs) have been proposed to be the central enzymes that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2015a85d4411ba48474f981a155c8556
https://doi.org/10.1126/sciadv.adf0133
https://doi.org/10.1126/sciadv.adf0133
Autor:
Roger Caothien, Charles Yu, Lucinda Tam, Robert Newman, Brian Nakao, Tuija Alcantar, Natasha Bacarro, Juan Reyes, Anna Pham, Merone Roose-Girma
Publikováno v:
Molecular Biology Reports. 49:3281-3288
Gene targeting in mouse ES cells replaces or modifies genes of interest; conditional alleles, reporter knock-ins, and amino acid changes are common examples of how gene targeting is used. For example, enhanced green fluorescent protein or Cre recombi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ad6f31ac7286698eaa66b488dad7cd3
https://doi.org/10.1007/s11033-022-07165-y
https://doi.org/10.1007/s11033-022-07165-y
Autor:
Charles Yu, Roger Caothien, Marques Jackson, Brian Nakao, Anna Pham, Lucinda Tam, Merone Roose-Girma
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7201a40d22dd298aefa6f9e3ee275123
https://doi.org/10.1007/978-1-0716-2990-1_7
https://doi.org/10.1007/978-1-0716-2990-1_7
Autor:
Charles Yu, Roger Caothien, Anna Pham, Lucinda Tam, Tuija Alcantar, Natasha Bacarro, Juan Reyes, Marques Jackson, Brian Nakao, Merone Roose-Girma
Publikováno v:
Methods in Molecular Biology ISBN: 9781071629895
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::012421f5ae13ec04c436d5c3b95bf2d6
https://doi.org/10.1007/978-1-0716-2990-1_5
https://doi.org/10.1007/978-1-0716-2990-1_5
Autor:
Jackson Liang, Ellen Rei Ingalla, Xiaosai Yao, Bu-Er Wang, Lisa Tai, Jennifer Giltnane, Yuxin Liang, Anneleen Daemen, Heather M. Moore, Junko Aimi, Ching-Wei Chang, Mary R. Gates, Jennifer Eng-Wong, Lucinda Tam, Natasha Bacarro, Merone Roose-Girma, Meritxell Bellet, Marc Hafner, Ciara Metcalfe
Publikováno v:
Science Translational Medicine. 14
ESR1 (estrogen receptor 1) hotspot mutations are major contributors to therapeutic resistance in estrogen receptor–positive (ER + ) breast cancer. Such mutations confer estrogen independence to ERα, providing a selective advantage in the presence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db5247251c7077fc1c909a8d471d77c2
https://doi.org/10.1126/scitranslmed.abo5959
https://doi.org/10.1126/scitranslmed.abo5959