Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lucile Broyer"'
Autor:
Anja Seckinger, Sara Majocchi, Valéry Moine, Lise Nouveau, Hoang Ngoc, Bruno Daubeuf, Ulla Ravn, Nicolas Pleche, Sebastien Calloud, Lucile Broyer, Laura Cons, Adeline Lesnier, Laurence Chatel, Anne Papaioannou, Susana Salgado-Pires, Sebastian Krämer, Ines Gockel, Florian Lordick, Krzysztof Masternak, Yves Poitevin, Giovanni Magistrelli, Pauline Malinge, Limin Shang, Sonja Kallendrusch, Klaus Strein, Dirk Hose
Publikováno v:
Journal of Hematology & Oncology, Vol 16, Iss 1, Pp 1-23 (2023)
Abstract Background T-cell retargeting to eliminate CEACAM5-expressing cancer cells via CEACAM5xCD3 bispecific antibodies (BsAbs) showed limited clinical activity so far, mostly due to insufficient T-cell activation, dose-limiting toxicities, and for
Externí odkaz:
https://doaj.org/article/30b29a2c343143119fd06970474edb47
Autor:
Eric Hatterer, Xavier Chauchet, Françoise Richard, Leticia Barba, Valéry Moine, Laurence Chatel, Lucile Broyer, Guillemette Pontini, Tereza Bautzova, Flora Juan, Sebastien Calloud, Nicolas Bosson, Maud Charreton, Krzysztof Masternak, Vanessa Buatois, Limin Shang
Publikováno v:
mAbs, Vol 12, Iss 1 (2020)
Mesothelin (MSLN) is a cell surface glycoprotein overexpressed in several solid malignancies, including gastric, lung, mesothelioma, pancreatic and ovarian cancers. While several MSLN-targeting therapeutic approaches are in development, only limited
Externí odkaz:
https://doaj.org/article/59bc1e85e0ff4934aa2869af212e6158
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
CD47, an ubiquitously expressed innate immune checkpoint receptor that serves as a universal “don't eat me” signal of phagocytosis, is often upregulated by hematologic and solid cancers to evade immune surveillance. Development of CD47-targeted m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d1610faf183edfbabdd336c0a26e78f
https://doi.org/10.1158/1535-7163.c.6538060.v1
https://doi.org/10.1158/1535-7163.c.6538060.v1
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
Supplementary Table S5 shows the hematological results of cynomolgus monkeys treated with vehicle (Ctr.) or NI-1701 (Treat.) at 30 and 100 mg/kg over 4 weeks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::203cc77da9079bee1c610c03ee5b49e7
https://doi.org/10.1158/1535-7163.22505443.v1
https://doi.org/10.1158/1535-7163.22505443.v1
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
Supplementary material and methods
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b418cfd8466c7d5dc25c91df055d57f2
https://doi.org/10.1158/1535-7163.22505458.v1
https://doi.org/10.1158/1535-7163.22505458.v1
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
Supplementary Figure S1 shows shows the percentage of in vitro phagocytosis of Raji cells by macrophages with NI-1701 or CD19/CD47hi biAb.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592d616e34724f770f64888467e08599
https://doi.org/10.1158/1535-7163.22505464
https://doi.org/10.1158/1535-7163.22505464
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
Video 1 shows the real time phagocytosis of cancer cells in presence of NI-1701
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a03b6ea47ab39912f01a7fe54bdc4554
https://doi.org/10.1158/1535-7163.22505440.v1
https://doi.org/10.1158/1535-7163.22505440.v1
Autor:
Walter G. Ferlin, Limin Shang, Nicolas Fischer, Krzysztof Masternak, Marie H. Kosco-Vilbois, John F. DiPersio, Michael Rettig, Julie Ritchey, Linda Eissenberg, Adele K. Fielding, Katharine Bailey, Aditi Dey, José María Ribera, Eulàlia Genescà Ferrer, Robert K. Clarke Hinojosa, Karin Tarte, Thierry Fest, Simon LeGallou, Thomas Matthes, Matilde D'Asaro, Lucile Broyer, Laura Cons, Bruno Daubeuf, Leticia Barba, Françoise Richard, Xavier Chauchet, Eric Hatterer, Anne Papaioannou, Susana Salgado-Pires, Zoë Johnson, Vanessa Buatois
Video 2 shows the real time phagocytosis of cancer cells in presence of hIgG1 control
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a76705390add379177b660b6a299aec9
https://doi.org/10.1158/1535-7163.22505437.v1
https://doi.org/10.1158/1535-7163.22505437.v1
Autor:
Leticia Barba, Françoise Richard, Nicolas Bosson, Flora Juan, Lucile Broyer, Eric Hatterer, Guillemette Pontini, Sébastien Calloud, Krzysztof Masternak, Valéry Moine, Limin Shang, Vanessa Buatois, Tereza Bautzova, Laurence Chatel, Maud Charreton, Xavier Chauchet
Publikováno v:
mAbs
Mesothelin (MSLN) is a cell surface glycoprotein overexpressed in several solid malignancies, including gastric, lung, mesothelioma, pancreatic and ovarian cancers. While several MSLN-targeting therapeutic approaches are in development, only limited
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90cb876be0807ee5292221f061afb0ea
https://doi.org/10.1080/19420862.2020.1739408
https://doi.org/10.1080/19420862.2020.1739408
Autor:
Laura Cons, Marie Kosco-Vilbois, Walter Ferlin, Valéry Moine, Sébastien Calloud, Stefano Majocchi, Elie Dheilly, Zoë Johnson, Lucile Broyer, François Rousseau, Krzysztof Masternak, Anne Papaioannou, Nicolas Fischer, Robert Nelson, Susana Salgado-Pires
Publikováno v:
Molecular Therapy
CD47 is a ubiquitously expressed immune checkpoint receptor that is often upregulated in cancer. CD47 interacts with its counter-receptor SIRPα on macrophages and other myeloid cells to inhibit cancer cell phagocytosis and drive immune evasion. To o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ce56a4fa03e6a69bc605f03aafcc3446