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pro vyhledávání: '"Lucile A. Gandon"'
Autor:
Alexander G. Russell, Angela E. Brodwolf, Benson M. Kariuki, Neil Spencer, John S. Snaith, Tatyana Gueveli, Lucile A. Gandon
Publikováno v:
The Journal of organic chemistry. 71(14)
A novel approach to 2,4-disubstituted piperidines is reported, involving the radical cyclization of 7-substituted-6-aza-8-bromooct-2-enoates. Cyclization with tributyltin hydride affords the trans piperidines with trans/cis diastereomeric ratios rang
Publikováno v:
ChemInform. 36
Cyclisation of bromides 4a-f mediated by tributyltin hydride affords predominantly the trans piperidines 5a-f with modest diastereomeric ratios, while cyclisation with tris(trimethylsilyl)silane affords the same products with diastereomeric ratios of