Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lucile, Noyer"'
Autor:
Valerio Farfariello, Dmitri V. Gordienko, Lina Mesilmany, Yasmine Touil, Emmanuelle Germain, Ingrid Fliniaux, Emilie Desruelles, Dimitra Gkika, Morad Roudbaraki, George Shapovalov, Lucile Noyer, Mathilde Lebas, Laurent Allart, Nathalie Zienthal-Gelus, Oksana Iamshanova, Franck Bonardi, Martin Figeac, William Laine, Jerome Kluza, Philippe Marchetti, Bruno Quesnel, Daniel Metzger, David Bernard, Jan B. Parys, Loïc Lemonnier, Natalia Prevarskaya
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-18 (2022)
Mitochondrial Ca2+ homeostasis is reported to influence cellular senescence. Here the authors show that TRPC3 limits senescence by inhibiting IP3R-mediated Ca2+ release and ER mitochondria Ca2+ transfer and that the downregulation of TRPC3 in stromal
Externí odkaz:
https://doaj.org/article/18e1a197a54f4fbebb56df91fdd44151
Autor:
Sascha Kahlfuss, Ulrike Kaufmann, Axel R Concepcion, Lucile Noyer, Dimitrius Raphael, Martin Vaeth, Jun Yang, Priya Pancholi, Mate Maus, James Muller, Lina Kozhaya, Alireza Khodadadi‐Jamayran, Zhengxi Sun, Patrick Shaw, Derya Unutmaz, Peter B Stathopulos, Cori Feist, Scott B Cameron, Stuart E Turvey, Stefan Feske
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 8, Pp 1-25 (2020)
Abstract Immunity to fungal infections is mediated by cells of the innate and adaptive immune system including Th17 cells. Ca2+ influx in immune cells is regulated by stromal interaction molecule 1 (STIM1) and its activation of the Ca2+ channel ORAI1
Externí odkaz:
https://doaj.org/article/5dea67d69b0a4240ad6b7dfd0ac39c79
Autor:
Charlotte Dubois, Artem Kondratskyi, Gabriel Bidaux, Lucile Noyer, Eric Vancauwenberghe, Valério Farfariello, Robert-Allain Toillon, Morad Roudbaraki, Dominique Tierny, Jean-Louis Bonnal, Natalia Prevarskaya, Fabien Vanden Abeele
Publikováno v:
iScience, Vol 23, Iss 7, Pp 101263- (2020)
Summary: Mitochondria are important cell death checkpoints, and mitochondrial Ca2+ overload is considered as a potent apoptotic intrinsic pathway inducer. Here, we report that this Ca2+ apoptosis link is largely ineffective in inducing cell-death jus
Externí odkaz:
https://doaj.org/article/c0c17992b4024f0b822437a2570c016d
Autor:
Aurélien Haustrate, George Shapovalov, Corentin Spriet, Clément Cordier, Artem Kondratskyi, Lucile Noyer, François Foulquier, Natalia Prevarskaya, V’yacheslav Lehen’kyi
Publikováno v:
Cancers
Cancers, 2023, 15 (6), pp.1825. ⟨10.3390/cancers15061825⟩
Cancers; Volume 15; Issue 6; Pages: 1825
Cancers, 2023, 15 (6), pp.1825. ⟨10.3390/cancers15061825⟩
Cancers; Volume 15; Issue 6; Pages: 1825
International audience; The TRPV6 calcium channel is known to be up-regulated in various tumors. The efforts to target the TRPV6 channel in vivo are still ongoing to propose an effective therapy against cancer. Here, we report the generation of two a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5aff14fde941896f93e36246c26b14
https://hal.science/hal-04122689
https://hal.science/hal-04122689
Autor:
Yin-Hu Wang, Lucile Noyer, Sascha Kahlfuss, Dimitrius Raphael, Anthony Y. Tao, Ulrike Kaufmann, Jingjie Zhu, Marisa Mitchell-Flack, Ikjot Sidhu, Fang Zhou, Martin Vaeth, Paul G. Thomas, Sean P. Saunders, Kenneth Stauderman, Maria A. Curotto de Lafaille, Stefan Feske
Publikováno v:
Science Advances. 8
T cell activation and function depend on Ca2+signals mediated by store-operated Ca2+entry (SOCE) through Ca2+release–activated Ca2+(CRAC) channels formed by ORAI1 proteins. We here investigated how SOCE controls T cell function in pulmonary inflamm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97f41a300cd2068b074b4e31d37468a
https://doi.org/10.1126/sciadv.abn6552
https://doi.org/10.1126/sciadv.abn6552
Autor:
Guillaume P. Grolez, Giorgia Chinigò, Alexandre Barras, Mehdi Hammadi, Lucile Noyer, Kateryna Kondratska, Etmar Bulk, Thibauld Oullier, Séverine Marionneau-Lambot, Marilyne Le Mée, Stéphanie Rétif, Stéphanie Lerondel, Antonino Bongiovanni, Tullio Genova, Sébastien Roger, Rabah Boukherroub, Albrecht Schwab, Alessandra Fiorio Pla, Dimitra Gkika
Publikováno v:
International Journal of Molecular Sciences
International Journal of Molecular Sciences, 2022, 23 (12), pp.6672. ⟨10.3390/ijms23126672⟩
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6672
International Journal of Molecular Sciences, 2022, Calcium Signaling in Human Health and Diseases 3.0, 23 (12), pp.6672. ⟨10.3390/ijms23126672⟩
International Journal of Molecular Sciences, 2022, 23 (12), pp.6672. ⟨10.3390/ijms23126672⟩
International Journal of Molecular Sciences; Volume 23; Issue 12; Pages: 6672
International Journal of Molecular Sciences, 2022, Calcium Signaling in Human Health and Diseases 3.0, 23 (12), pp.6672. ⟨10.3390/ijms23126672⟩
International audience; In the fight against prostate cancer (PCa), TRPM8 is one of the most promising clinical targets. Indeed, several studies have highlighted that TRPM8 involvement is key in PCa progression because of its impact on cell prolifera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22108dc2db8c1b55236c731270251fc1
https://pubmed.ncbi.nlm.nih.gov/35743115
https://pubmed.ncbi.nlm.nih.gov/35743115
Autor:
Krishna P. Subedi, Rajesh Bhardwaj, Indu S. Ambudkar, Hassan Saadi, Hwei Ling Ong, Changyu Zheng, Stefan Feske, Ga-Yeon Son, Lucile Noyer
Publikováno v:
Proceedings of the National Academy of Sciences. 117:16638-16648
The Orai1 channel is regulated by stromal interaction molecules STIM1 and STIM2 within endoplasmic reticulum (ER)-plasma membrane (PM) contact sites. Ca2+ signals generated by Orai1 activate Ca2+-dependent gene expression. When compared with STIM1, S
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe97cf819c3acf3329c989aa1037a1e7
https://doi.org/10.1073/pnas.1915386117
https://doi.org/10.1073/pnas.1915386117
Autor:
Liwei Wang, Lucile Noyer, Yin-Hu Wang, Anthony Y. Tao, Wenyi Li, Jingjie Zhu, Pedro Saavedra, Syed T. Hoda, Jun Yang, Stefan Feske
Publikováno v:
The Journal of general physiology. 154(10)
Ca2+ signals regulate the function of many immune cells and promote immune responses to infection, cancer, and autoantigens. Ca2+ influx in immune cells is mediated by store-operated Ca2+ entry (SOCE) that results from the opening of Ca2+ release-act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3b4156659c3f514312395a9f64740d2
https://pubmed.ncbi.nlm.nih.gov/35861698
https://pubmed.ncbi.nlm.nih.gov/35861698
Autor:
Ga-Yeon, Son, Krishna Prasad, Subedi, Hwei Ling, Ong, Lucile, Noyer, Hassan, Saadi, Changyu, Zheng, Rajesh, Bhardwaj, Stefan, Feske, Indu Suresh, Ambudkar
Publikováno v:
Proc Natl Acad Sci U S A
The Orai1 channel is regulated by stromal interaction molecules STIM1 and STIM2 within endoplasmic reticulum (ER)-plasma membrane (PM) contact sites. Ca(2+) signals generated by Orai1 activate Ca(2+)-dependent gene expression. When compared with STIM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ced2031a05bddfd2e7b1dc2fa1e7bd23
https://pubmed.ncbi.nlm.nih.gov/32601188
https://pubmed.ncbi.nlm.nih.gov/32601188
Publikováno v:
Pflügers Archiv - European Journal of Physiology. 470:1419-1429
While originally cloned from the prostate in 2001, transient receptor potential, melastatin member 8 (TRPM8) has since been identified as the cold/menthol receptor in the peripheral nervous system. This discovery has led to hundreds of studies regard
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::630e2c55335d80b676380c6ed4302b9f
https://doi.org/10.1007/s00424-018-2169-1
https://doi.org/10.1007/s00424-018-2169-1