Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Lucien Nedelec"'
Publikováno v:
Tetrahedron. 30:3263-3268
Addition at very low temperature of potassium t-butoxide to a solution of an α,β-unsaturated ketone and methyl iodide in tetrahydrofuran allows methylation at the methylenic position α′, via the kinetic enolate. The reaction leads easily to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::647658be6d64678aa1933a3e9aca49fb
https://doi.org/10.1016/s0040-4020(01)97498-8
https://doi.org/10.1016/s0040-4020(01)97498-8
Publikováno v:
Tetrahedron. 34:2729-2736
Resume On decrit la preparation des isomeres α et β en position 2 des dimethyl-2,17 hydroxy-17β estradiene-4,9 ones-3, 4 , et des dimethyl-2,17 hydroxy-17β estratriene-4,9,11 ones-3, 21 . La configuration en 2 estetablie par voie chimique. Les co
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e7dab95728e21fb7aa80b2e97bd4762a
https://doi.org/10.1016/0040-4020(78)88411-7
https://doi.org/10.1016/0040-4020(78)88411-7
Publikováno v:
Tetrahedron. 36:1763-1772
A total synthesis of (±) negamycine 1 has been achieved in 14 steps from the acrolein dimer 6, which possesses the same carbon skeleton as the key intermediate lactone 4. Treatment of 2-acetoxymethyl 3,4-dihydro[2H]pyran 8, obtained from 6, with lea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fb4eb20d9243afffa5922d4c857a9c28
https://doi.org/10.1016/0040-4020(80)80072-x
https://doi.org/10.1016/0040-4020(80)80072-x
Publikováno v:
Steroids. 51:465-469
Fluorescent spirolactone derivatives are obtained by coupling 3-carboxylic coumarins to a spirolactone bearing a 3-hydroxypropyl chain in the 7α position. The two esters prepared by this method are highly fluorescent (emission 383 and 408 nm).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d6b32682fd36871765981c5a512827f3
https://doi.org/10.1016/0039-128x(88)90045-1
https://doi.org/10.1016/0039-128x(88)90045-1
Autor:
Lucien Nedelec, Jean Jacques, Hilda Morales-Alanis, Marie Josephe Brienne, Colette Tournemine, Vesperto Torelli, M.-M. Bouton
Publikováno v:
Journal of Medicinal Chemistry. 28:1796-1803
In the search for new antiandrogens, a number of des-A-steroids were prepared by condensation of Grignard reagents with lactone 3. From the resulting key intermediates 5, various structural modifications were performed such as the introduction of an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d608f239ae7b7149372b011c612d9d0f
https://doi.org/10.1021/jm00150a009
https://doi.org/10.1021/jm00150a009
Publikováno v:
Tetrahedron. 35:2681-2692
Room and low-temperature CD of the title dienones and trienones ( 3 to 9 ) clearly show that a conformational equilibrium occurs between two ring A half-chair conformers. The relative stability of the two conformers depends on substitution of ring A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c5e6c3505c87bfc77201ad58dd45a1f3
https://doi.org/10.1016/0040-4020(79)87050-7
https://doi.org/10.1016/0040-4020(79)87050-7
Publikováno v:
European Journal of Medicinal Chemistry. 22:33-43
Resume La synthese et les resultats de l'etude des proprietes serotoninergiques et/ou anti-dopaminergiques d'une serie de (tetrahydro-1,2,3,6 pyridinyl-4)-3 1H-indoles substitues ou non sur le noyau indolique sont presentes. La plupart des composes o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3f3520877f1b02acb560eaa95417e4e8
https://doi.org/10.1016/0223-5234(87)90172-3
https://doi.org/10.1016/0223-5234(87)90172-3
Publikováno v:
J. Chem. Soc., Chem. Commun.. :775-777
α-Formylaminoacrylic esters, produced by the condensation of ethyl isocyanoacetate with 17-oxo-steroids, have been reduced selectively to give the corresponding alcohols; the latter gave, in high yield, the hydroxyacetyl side-chain on acidic hydroly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c38b4e6183ef34e21cd7949e6fac3fe0
https://doi.org/10.1039/c39810000775
https://doi.org/10.1039/c39810000775
Publikováno v:
Chemischer Informationsdienst. 9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a5483683d26a797b604b904302b6f35d
https://doi.org/10.1002/chin.197835312
https://doi.org/10.1002/chin.197835312
Publikováno v:
Chemischer Informationsdienst. 10
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::73b2172c609872ce8d9348e134b20cc3
https://doi.org/10.1002/chin.197902318
https://doi.org/10.1002/chin.197902318