Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Lucie Vandromme"'
Publikováno v:
European Journal of Organic Chemistry. 2014:4985-4992
Flexible and straightforward syntheses of a series of D3h- or C3h-symmetrical star-shaped compounds with pyridine end groups are reported. In all cases, the acid-mediated cyclocondensations of the corresponding aryl methyl ketone provided the central
Publikováno v:
Synlett. 2009:1614-1618
In the reaction with tert-butyloxycarbonyl anhydride (Boc 2 O), N-(o-vinylacetyloxy)benzenesulfonyl allylic amines 4a―c undergo concomitant O to N acyl migration to give N-(o-vinyl-acetyloxy)-N-(o-tert-butoxycarbonyloxy)benzenesulfonyl allylic amin
Publikováno v:
European Journal of Organic Chemistry. 2008:2049-2055
We report the synthesis of a series of 2,6-disubstitutedpyridines in a straightforward manner starting from readily available 2-substituted pyridines. The main sequence involves a selective α-lithiation reaction with halogen functionalization follow
Autor:
Olivier Lafon, Marie-Elise Tran Huu Dau, Li Chen, Philippe Lesot, Françoise Dumas, Pierre Chaminade, André Loupy, Franck Le Bideau, Lai Wei, Lucie Vandromme
Publikováno v:
Proceedings of MOL2NET, International Conference on Multidisciplinary Sciences.
In connection with synthetic applications, we have foreseen to study the reactivity of the poorly reactive tert-butyl acrylate electrophile with chiral imines of unsymmetrical ketones, using conventional or microwave flash heating under carefully con
Publikováno v:
SYNLETT
SYNLETT, Georg Thieme Verlag, 2006, 2006 (20), pp.3423-3426. ⟨10.1055/s-2006-956483⟩
SYNLETT, Georg Thieme Verlag, 2006, 2006 (20), pp.3423-3426. ⟨10.1055/s-2006-956483⟩
International audience
Autor:
Wahib Hamchaoui, Olivier Barbeau, Michel Wakselman, Lucie Vandromme, Jean-Paul Mazaleyrat, Anne Gaucher, Karen Wright
Publikováno v:
Tetrahedron Letters. 43:8241-8244
Terminally protected Boc-β3-(L)-DOPA-OMe has been synthesized from (L)-DOPA by the Arndt–Eistert homologation procedure. Then, a first crown-ether derivative, Boc-[18-C-6]-β3-(L)-DOPA-OMe, has been obtained by bis-O-alkylation of the catechol fun
Autor:
Antoine Fadel, Lucie Vandromme
Publikováno v:
Tetrahedron: Asymmetry. 10:1153-1162
From a single chiron, the homochiral benzylic malonic acid ester (R)-(+)-2 available with high enantiomeric excess by enzymatic hydrolysis (PLE acetonic powder), enantiomerically pure (−)-sporochnol A 1 was prepared. This versatile method allows pr
ChemInform Abstract: Total Synthesis of (-)-Sporochnol A, the Fish Deterrent, from a Chiral Malonate
Autor:
Lucie Vandromme, Antoine Fadel
Publikováno v:
ChemInform. 30
From a single chiron, the homochiral benzylic malonic acid ester (R)-(+)-2 available with high enantiomeric excess by enzymatic hydrolysis (PLE acetonic powder), enantiomerically pure (−)-sporochnol A 1 was prepared. This versatile method allows pr
Autor:
Olivier Lozach, Laurent Meijer, Sergio Kreimerman, Michel Legraverend, Lucie Vandromme, David S. Grierson
Publikováno v:
Bioorganic and Medicinal Chemistry
Bioorganic and Medicinal Chemistry, Elsevier, 2007, 15 (1), pp.130-41. ⟨10.1016/j.bmc.2006.10.003⟩
Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp.130-41. ⟨10.1016/j.bmc.2006.10.003⟩
Bioorganic and Medicinal Chemistry, Elsevier, 2007, 15 (1), pp.130-41. ⟨10.1016/j.bmc.2006.10.003⟩
Bioorganic and Medicinal Chemistry, 2007, 15 (1), pp.130-41. ⟨10.1016/j.bmc.2006.10.003⟩
Two new series of 2-amido- and 2-aminocarbonylpurines have been synthesized using a Pd catalyst cross-coupling reaction either with amides or amines in the presence of CO. Moderate in vitro inhibitory activity against CDK1 and CDK5 was observed with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33dc48b5cee0ef6911f5161904dfd3b4
https://hal.archives-ouvertes.fr/hal-00169386
https://hal.archives-ouvertes.fr/hal-00169386
Autor:
David S. Grierson, Sandrine Piguel, Olivier Lozach, Lucie Vandromme, Laurent Meijer, Michel Legraverend
Publikováno v:
ChemInform. 37
A new series of 2-aryl-substituted purine derivatives has been synthesized by Suzuki Pd(0) coupling reactions. Moderate in vitro inhibitory activity against Cdk1 and Cdk5 was observed. These compounds are inactive against GSK3.