Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lucie Sromova"'
Autor:
Petr Busek, Helena Posova, Michal Andel, Pavel Škrha, Jana Potockova, Aleksi Sedo, Lucie Sromova
Publikováno v:
Diabetes Research and Clinical Practice. 118:183-192
Aim To assess intraindividually the effects of DPP-IV inhibition on the subpopulations of immune cells in type 2 diabetes mellitus (DM2) patients during the course of treatment with sitagliptin. Methods In this open label non-randomized observational
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe699aee2801dbc3cffa9bf663f18eda
https://doi.org/10.1016/j.diabres.2016.06.020
https://doi.org/10.1016/j.diabres.2016.06.020
Autor:
Ondrej Slaby, Jiri Sana, Marek Hilser, Martin Smrčka, Radim Lipina, Lenka Radová, Lucie Sromova, Štefan Reguli, Aleksi Sedo, Petr Busek, Radek Lakomy, Leos Kren, Andrej Bešše, Pavel Fadrus, Marek Vecera
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-11 (2018)
Glioblastoma stem-like cells (GSCs) are critical for the aggressiveness and progression of glioblastoma (GBM) and contribute to its resistance to adjuvant treatment. MicroRNAs (miRNAs) are small, non-coding RNAs controlling gene expression at the pos
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7bf1879f607568565170dd87f48d1086
http://europepmc.org/articles/PMC5809429
http://europepmc.org/articles/PMC5809429
Autor:
Jan Konvalinka, Petra Dvořáková, Petr Busek, Tomáš Knedlík, Libor Kostka, Aleksi Sedo, Tomáš Etrych, Pavel Šácha, Vladimir Subr, Lucie Sromova, Jiří Schimer
Publikováno v:
Journal of medicinal chemistry. 60(20)
Proteases are directly involved in cancer pathogenesis. Expression of fibroblast activation protein (FAP) is upregulated in stromal fibroblasts in more than 90% of epithelial cancers and is associated with tumor progression. FAP expression is minimal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7285ab55d6e3701551ade6a27580345b
https://pubmed.ncbi.nlm.nih.gov/28953383
https://pubmed.ncbi.nlm.nih.gov/28953383
Autor:
Michal, Andel, Pavel, Skrha, Pavel, Kraml, Jana, Potockova, Iva, Hoffmanova, Elena, Silhova, Josef, Fontana, Anna, Richterova, Martin, Gadiredi, Petr, Busek, Lucie, Sromova, Aleksi, Šedo
Publikováno v:
Vnitrni lekarstvi. 62(6)
We present the results of an independent, drug company-unsupported follow-up of patients with type 2 diabetes mellitus (T2DM) treated with the dipeptidyl peptidase 4 inhibitor sitagliptin. 29 patients (16 men, 13 women) used sitagliptin 100 mg daily
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::20b10897d777a7bfceb0d73dc93b6a28
https://pubmed.ncbi.nlm.nih.gov/27485843
https://pubmed.ncbi.nlm.nih.gov/27485843
Autor:
Jarmila Stremenova, Petr Busek, Eva Balaziova, Evzen Krepela, Aleksi Sedo, Lucie Sromova, Hynek Strnad, Dalibor Kosek, Marek Hilser, Jana Trylcova
Publikováno v:
The International Journal of Biochemistry & Cell Biology. 44:738-747
Malignant gliomas exhibit abnormal expression of proteolytic enzymes that may participate in the uncontrolled cell proliferation and aberrant interactions with the brain extracellular matrix. The multifunctional membrane bound serine aminopeptidase d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f121d3bdd47d4c1a0b0925fcbbf98ce
https://doi.org/10.1016/j.biocel.2012.01.011
https://doi.org/10.1016/j.biocel.2012.01.011
Autor:
Petr Busek, Lucie Sromova, Libuse Lizcova, Jarmila Stremenova, Evzen Krepela, Aleksi Sedo, Eva Balaziova
Publikováno v:
Molecular and Cellular Biochemistry. 354:283-289
Dipeptidyl peptidase-IV (DPP-IV) and fibroblast activation protein-α (FAP) are speculated to participate in the regulation of multiple biological processes, because of their unique enzymatic activity, as well as by non-hydrolytic molecular interacti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::394c51235591367defd196005d8f2fc3
https://doi.org/10.1007/s11010-011-0828-z
https://doi.org/10.1007/s11010-011-0828-z
Publikováno v:
Clinica Chimica Acta. 411:1046-1050
Background Dipeptidyl peptidase-IV (DPP-IV) enzymatic activity controls biological halftime of multiple local mediators. Its deregulation is associated with pathogenesis of several autoimmune diseases, including rheumatoid arthritis (RA). Although DP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66a271b80e8609c917276fe2fd3ab13f
https://doi.org/10.1016/j.cca.2010.03.034
https://doi.org/10.1016/j.cca.2010.03.034
Autor:
Lucie Sromova, Evzen Krepela, Aleksi Sedo, Marek Hilser, Eva Balaziova, I. Vomelova, Petr Busek
Publikováno v:
Europe PubMed Central
Fibroblast activation protein alpha (FAP) is a dual specificity serine protease that is strongly associated with the development and progression of human carcinomas and represents a potential stromal target for anticancer treatment. Due to its gelati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37a234d97c31058a53b61082936fd190
https://europepmc.org/articles/PMC4185866/
https://europepmc.org/articles/PMC4185866/
Publikováno v:
BMC Musculoskeletal Disorders
Background Dipeptidyl peptidase-IV (DPP-IV) is suggested to contribute to the pathogenesis of several autoimmune diseases. The aim of this study was to evaluate the association of DPP-IV presence in blood plasma and mononuclear cells with the disease
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1aef41bb88ec321cc825825299bef5aa