Proteomic Characterization of Human Neural Stem Cells and Their Secretome During in vitro Differentiation

Autor: Jakub Červenka, Jiřina Tylečková, Helena Kupcová Skalníková, Kateřina Vodičková Kepková, Ievgeniia Poliakh, Ivona Valeková, Lucie Pfeiferová, Michal Kolář, Michaela Vaškovičová, Tereza Pánková, Petr Vodička

Publikováno v: Frontiers in Cellular Neuroscience, Vol 14 (2021)

Cell therapies represent a promising approach to slow down the progression of currently untreatable neurodegenerative diseases (e.g., Alzheimer's and Parkinson's disease or amyotrophic lateral sclerosis), as well as to support the reconstruction of f

Externí odkaz: https://doaj.org/article/d1bb9a3dcc2e40f0a9e3e6cba493de5e

TROP2 represents a negative prognostic factor in colorectal adenocarcinoma and its expression is associated with features of epithelial-mesenchymal transition and invasiveness

Autor: Jiří Švec, Monika Šťastná, Lucie Janečková, Dušan Hrčkulák, Martina Vojtěchová, Jakub Onhajzer, Vítězslav Kříž, Kateřina Galušková, Eva Šloncová, Jan Kubovčiak, Lucie Pfeiferová, Jan Hrudka, Radoslav Matěj, Petr Waldauf, Lukáš Havlůj, Michal Kolář, Vladimír Kořínek

Publikováno v: Cancers; Volume 14; Issue 17; Pages: 4137

Trophoblastic cell surface antigen 2 (TROP2) is a membrane glycoprotein overexpressed in many solid tumors with poor prognosis, including intestinal neoplasms. In our study, we show that TROP2 is expressed in preneoplastic lesions and its expression

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2593464efdbdfaffcb270bc1fb339bd
https://doi.org/10.1101/2022.07.27.501720

Proteomic Characterization of Human Neural Stem Cells and Their Secretome During

Autor: Petr Vodicka, Tereza Pánková, Lucie Pfeiferová, Katerina Vodickova Kepkova, Jiřina Tylečková, Ievgeniia Poliakh, Jakub Cervenka, Helena Kupcova Skalnikova, Ivona Valekova, Michal Kolář, Michaela Vaškovičová

Publikováno v: Frontiers in Cellular Neuroscience
Frontiers in Cellular Neuroscience, Vol 14 (2021)

Cell therapies represent a promising approach to slow down the progression of currently untreatable neurodegenerative diseases (e.g., Alzheimer's and Parkinson's disease or amyotrophic lateral sclerosis), as well as to support the reconstruction of f

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02b5a6f01482979ce55ac0c2ec11f4ca
https://pubmed.ncbi.nlm.nih.gov/33584205

Artificial proteins as allosteric modulators of PDZ3 and SH3 in two-domain constructs: A computational characterization of novel chimeric proteins

Autor: Palani, Kirubakaran, Lucie, Pfeiferová, Kristýna, Boušová, Lucie, Bednarova, Veronika, Obšilová, Jiří, Vondrášek

Publikováno v: Proteins. 84(10)

Artificial multidomain proteins with enhanced structural and functional properties can be utilized in a broad spectrum of applications. The design of chimeric fusion proteins utilizing protein domains or one-domain miniproteins as building blocks is

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ef75bce623178bcc3c4bdb54c40a1344
https://pubmed.ncbi.nlm.nih.gov/27273513

Exome sequencing reveals IFT172 variants in patients with non-syndromic cholestatic liver disease.

Autor: Neřoldová, Magdaléna^1,2 (AUTHOR), Ciara, Elżbieta³ (AUTHOR), Slatinská, Janka¹ (AUTHOR), Fraňková, Soňa¹ (AUTHOR), Lišková, Petra^4,5 (AUTHOR), Kotalová, Radana⁶ (AUTHOR), Globinovská, Janka⁷ (AUTHOR), Šafaříková, Markéta² (AUTHOR), Pfeiferová, Lucie^2,8 (AUTHOR), Zůnová, Hana⁹ (AUTHOR), Mrázová, Lenka⁵ (AUTHOR), Stránecký, Viktor⁵ (AUTHOR), Vrbacká, Alena⁵ (AUTHOR), Fabián, Ondřej^1,10 (AUTHOR), Sticová, Eva¹ (AUTHOR), Skanderová, Daniela¹¹ (AUTHOR), Šperl, Jan¹ (AUTHOR), Kalousová, Marta² (AUTHOR), Zima, Tomáš² (AUTHOR), Macek, Milan⁹ (AUTHOR)

Publikováno v: PLoS ONE. 7/20/2023, Vol. 18 Issue 7, p1-15. 15p.