Zobrazeno 1 - 10
of 61
pro vyhledávání: '"Lucie Petrásková"'
Autor:
Viola Kolaříková, Katerina Brodsky, Lucie Petrásková, Helena Pelantová, Josef Cvačka, Libor Havlíček, Vladimír Křen, Kateřina Valentová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 23, p 15171 (2022)
Phenolic acids are known flavonoid metabolites, which typically undergo bioconjugation during phase II of biotransformation, forming sulfates, along with other conjugates. Sulfated derivatives of phenolic acids can be synthesized by two approaches: c
Externí odkaz:
https://doaj.org/article/9f6f3a2532b94d36af80c931e26bcdd0
Autor:
Pavlína Nekvasilová, Natalia Kulik, Michael Kotik, Lucie Petrásková, Kristýna Slámová, Vladimír Křen, Pavla Bojarová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 20, p 12456 (2022)
β-N-Acetylhexosaminidase from Talaromyces flavus (TfHex; EC 3.2.1.52) is an exo-glycosidase with dual activity for cleaving N-acetylglucosamine (GlcNAc) and N-acetylgalactosamine (GalNAc) units from carbohydrates. By targeting a mutation hotspot of
Externí odkaz:
https://doaj.org/article/64c7f20594a4404a8fd9166fdb667773
Autor:
Lucie Petrásková, Kristýna Káňová, Katerina Brodsky, Anastasiia Hetman, Barbora Petránková, Helena Pelantová, Vladimír Křen, Kateřina Valentová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 10, p 5743 (2022)
Sulfation is an important reaction in nature, and sulfated phenolic compounds are of interest as standards of mammalian phase II metabolites or pro-drugs. Such standards can be prepared using chemoenzymatic methods with aryl sulfotransferases. The ai
Externí odkaz:
https://doaj.org/article/456a63c318ba480eb725c2d64c32fdeb
Autor:
Pavlína Nekvasilová, Michaela Hovorková, Zuzana Mészáros, Lucie Petrásková, Helena Pelantová, Vladimír Křen, Kristýna Slámová, Pavla Bojarová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 8, p 4106 (2022)
Enzymatic synthesis is an elegant biocompatible approach to complex compounds such as human milk oligosaccharides (HMOs). These compounds are vital for healthy neonatal development with a positive impact on the immune system. Although HMOs may be pre
Externí odkaz:
https://doaj.org/article/5f202e60149f4a7985245b45ceecaca3
Autor:
Ludmila Martínková, Romana Příhodová, Natalia Kulik, Helena Pelantová, Barbora Křístková, Lucie Petrásková, David Biedermann
Publikováno v:
Catalysts, Vol 10, Iss 9, p 1077 (2020)
Catechols are antioxidants and radical scavengers with a broad medical potential. 4-Methylcatechol (1b) and 4-ethylcatechol (2b) (occurring in some traditional fermented and smoked foods) activate the cell defense against oxidative stress. We examine
Externí odkaz:
https://doaj.org/article/ea9809766cdd4a3085a6107376f38bf0
Autor:
Lenka Rucká, Natalia Kulik, Petr Novotný, Anastasia Sedova, Lucie Petrásková, Romana Příhodová, Barbora Křístková, Petr Halada, Miroslav Pátek, Ludmila Martínková
Publikováno v:
Molecules, Vol 25, Iss 17, p 3861 (2020)
Fungi contain many plant-nitrilase (NLase) homologues according to database searches. In this study, enzymes NitTv1 from Trametes versicolor and NitAb from Agaricus bisporus were purified and characterized as the representatives of this type of funga
Externí odkaz:
https://doaj.org/article/f700cbc064704bbfa53349ce17be6822
Autor:
Simona Dobiasová, Kateřina Řehořová, Denisa Kučerová, David Biedermann, Kristýna Káňová, Lucie Petrásková, Kamila Koucká, Radka Václavíková, Kateřina Valentová, Tomáš Ruml, Tomáš Macek, Vladimír Křen, Jitka Viktorová
Publikováno v:
Antioxidants, Vol 9, Iss 5, p 455 (2020)
Silybin is considered to be the main biologically active component of silymarin. Its oxidized derivative 2,3-dehydrosilybin typically occurs in silymarin in small, but non-negligible amounts (up to 3%). Here, we investigated in detail complex biologi
Externí odkaz:
https://doaj.org/article/0e35c074cfce47bda7ec0dd80d261801
Autor:
Kateřina Valentová, Jaroslav Havlík, Pavel Kosina, Barbora Papoušková, José Diógenes Jaimes, Kristýna Káňová, Lucie Petrásková, Jitka Ulrichová, Vladimír Křen
Publikováno v:
Metabolites, Vol 10, Iss 1, p 29 (2020)
Flavonolignans occur typically in Silybum marianum (milk thistle) fruit extract, silymarin, which contains silybin, isosilybin, silychristin, silydianin, and their 2,3-dehydroderivatives, together with other minor flavonoids and a polymeric phenolic
Externí odkaz:
https://doaj.org/article/9ef7a36562234e7fbfff12dffff593e2
Publikováno v:
Foods, Vol 9, Iss 2, p 116 (2020)
Herbal preparations from Silybum marianum have been used since the fourth century BC in liver disease treatment and against numerous other pathologies. Consumption of silymarin containing drugs and food supplements continues to increase. Precise, fas
Externí odkaz:
https://doaj.org/article/ace66ac9015641bdbab94c35d3c7e225
Autor:
Jana Pourová, Lenka Applová, Kateřina Macáková, Marie Vopršalová, Thomas Migkos, Roger Bentanachs, David Biedermann, Lucie Petrásková, Václav Tvrdý, Marcel Hrubša, Jana Karlíčková, Vladimír Křen, Kateřina Valentová, Přemysl Mladěnka
Publikováno v:
Nutrients, Vol 11, Iss 10, p 2286 (2019)
Silymarin is a traditional drug and food supplement employed for numerous liver disorders. The available studies indicate that its activities may be broader, in particular due to claimed benefits in some cardiovascular diseases, but the contributions
Externí odkaz:
https://doaj.org/article/25c95dcbd8904239b0f3f87ab738b15e