HLA-DR-Restricted Peptides Identified in The Nef Protein Can Induce HIV Type 1-Specific IL-2/IFN-γ-Secreting CD4+And CD4+/CD8+T Cells in Humans after Lipopeptide Vaccination

Autor: Jean-Gérard Guillet, Bernard Maillere, Sandra Pouvelle-Moratille, Mathieu Surenaud, Hanne Gahery, Lucie Ourth, Catherine Texier, Céline Igea, Suzanne Figueiredo

Publikováno v: AIDS Research and Human Retroviruses
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2007, 23 (3), pp.427-37. ⟨10.1089/aid.2006.0075⟩
AIDS Research and Human Retroviruses, Mary Ann Liebert, 2007, 23 (3), pp.427-37. 〈10.1089/aid.2006.0075〉

International audience; We screened the Neflaiprotein to identify new HLA-DR-restricted epitopes, because this small protein is expressed early during infection, and specific CD4(+) T cells are critical for effective immunity in HIV-1 infection. We s

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22366f071b56956848646f0c8f962fda
https://doi.org/10.1089/aid.2006.0075

Mice transgenic for the human myotonic dystrophy region with expanded CTG repeats display muscular and brain abnormalities

Autor: Claudine Junien, Nacira Tabti, Chantal Duros, Cédric Savouret, Nicolas Sergeant, Antoine Ghestem, Hervé Seznec, Gillian Butler-Browne, Onnik Agbulut, Geneviève Gourdon, Edith Brisson, Jean-Claude Willer, Lucie Ourth, André Delacourte, Coralie Fouquet

Publikováno v: Scopus-Elsevier
Human Molecular Genetics
Human Molecular Genetics, Oxford University Press (OUP), 2001, 10, pp.2717-2726
Human Molecular Genetics, 2001, 10, pp.2717-2726

The autosomal dominant mutation causing myotonic dystrophy (DM1) is a CTG repeat expansion in the 3'-UTR of the DM protein kinase (DMPK) gene. This multisystemic disorder includes myotonia, progressive weakness and wasting of skeletal muscle and extr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ddeb510f331ea33cbb6528d319763f6
https://doi.org/10.1093/hmg/10.23.2717

New CD4+ and CD8+ T Cell Responses Induced in Chronically HIV Type-1-Infected Patients After Immunizations with an HIV Type 1 Lipopeptide Vaccine.

Autor: Hanne Gahery, Nathalie Daniel, Bénédicte Charmeteau, Lucie Ourth, Angéla Jackson, Muriel Andrieu, Jeannine Choppin, Dominique Salmon, Gilles Pialoux, Jean-Gerard Guillet

Publikováno v: AIDS Research & Human Retroviruses; Jul2006, Vol. 22 Issue 7, p684-694, 11p