Zobrazeno 1 - 10
of 72
pro vyhledávání: '"Lucie Muchová"'
Autor:
Esther M. Sánchez-Carnerero, Marina Russo, Andreas Jakob, Lucie Muchová, Libor Vítek, Petr Klán
Publikováno v:
Chemistry, Vol 3, Iss 1, Pp 238-255 (2021)
Carbon monoxide (CO) is an endogenously produced signaling molecule involved in the control of a vast array of physiological processes. One of the strategies to administer therapeutic amounts of CO is the precise spatial and temporal control over its
Externí odkaz:
https://doaj.org/article/01f55dfd943d42d8bff69d81f66968e5
Autor:
Aleš Dvořák, Kateřina Pospíšilová, Kateřina Žížalová, Nikola Capková, Lucie Muchová, Marek Vecka, Nikola Vrzáčková, Jana Křížová, Jaroslav Zelenka, Libor Vítek
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
For severe unconjugated hyperbilirubinemia the gold standard treatment is phototherapy with blue-green light, producing more polar photo-oxidation products, believed to be non-toxic. The aim of the present study was to compare the effects of bilirubi
Externí odkaz:
https://doaj.org/article/0e9bfb44b6434ae1809c220696b82a75
Autor:
Mária Šranková, Aleš Dvořák, Marek Martínek, Peter Šebej, Petr Klán, Libor Vítek, Lucie Muchová
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 3, p 1504 (2022)
Fluorescein is a fluorescent dye used as a diagnostic tool in various fields of medicine. Although fluorescein itself possesses low toxicity, after photoactivation, it releases potentially toxic molecules, such as singlet oxygen (1O2) and, as we demo
Externí odkaz:
https://doaj.org/article/599d3912032d405ba5f8195ce9d51ade
Autor:
Renata Koníčková, Kateřina Vaňková, Jana Vaníková, Katerina Vánová, Lucie Muchová, Iva Subhanová, Marie Zadinová, Jaroslav Zelenka, Ales Dvořák, Michal Kolář, Hynek Strnad, Silvie Rimpelová, Tomas Ruml, Ronald J. Wong, Libor Vítek
Publikováno v:
Annals of Hepatology, Vol 13, Iss 2, Pp 273-283 (2014)
Spirulina platensis is a blue-green alga used as a dietary supplement because of its hypocholesterolemic properties. Among other bioactive substances, it is also rich in tetrapyrrolic compounds closely related to bilirubin molecule, a potent antioxid
Externí odkaz:
https://doaj.org/article/27fb99bbdf824f9f9ac1cb2c7b0e5c4e
Autor:
Petr Urbánek, Martin Leníček, Lucie Muchová, Iva Subhanová, Ladislav Dušek, Nikola Kaspříkova, Petr Hrabal, Radan Brůha, Libor Vítek
Publikováno v:
Annals of Hepatology, Vol 10, Iss 4, Pp 445-451 (2011)
Background. Heme oxygenase-1 (HMOX1) and bilirubin UDP-glucuronosyltransferase (UGT1A1), both enzymes involved in bilirubin homeostasis, play an important role inoxidative stress defense.Objective. To assess the effect of promotervariations of HMOX1
Externí odkaz:
https://doaj.org/article/59f7a99e9d904c218f305fb439efa650
Autor:
Dominik Madea, Taufiqueahmed Mujawar, Aleš Dvořák, Kateřina Pospíšilová, Lucie Muchová, Petra Čubáková, Miroslav Kloz, Jakub Švenda, Libor Vítek, Petr Klán
Publikováno v:
The Journal of Organic Chemistry. 87:3089-3103
Autor:
Marek Martínek, Lucie Ludvíková, Mária Šranková, Rafael Navrátil, Lucie Muchová, Jiří Huzlík, Libor Vítek, Petr Klán, Peter Šebej
Publikováno v:
Organicbiomolecular chemistry.
Fluorescein, eosin Y, and rose bengal are dyes used in clinical medicine and considered (photo-)chemically stable. Upon extensive irradiation with visible light in aqueous solutions, we found that these compounds release carbon monoxide (CO) - a bioa
Autor:
Marina Russo, Vojtěch Orel, Peter Štacko, Mária Šranková, Lucie Muchová, Libor Vítek, Petr Klán
Carbon monoxide (CO) is an endogenous signaling molecule that regulates diverse physiological processes. The therapeutic potential of CO is hampered by its intrinsic toxicity, and its administration poses a significant challenge. Photoactivatable CO-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::24902be17e76237f1f216818a91bc853
https://doi.org/10.5167/uzh-226713
https://doi.org/10.5167/uzh-226713
Publikováno v:
The Journal of Organic Chemistry. 85:3473-3489
Carbon monoxide (CO) is a cell-signaling molecule (gasotransmitter) produced endogenously by oxidative catabolism of heme, and the understanding of its spatial and temporal sensing at the cellular level is still an open challenge. Synthesis, optical
Autor:
Dominik, Madea, Taufiqueahmed, Mujawar, Aleš, Dvořák, Kateřina, Pospíšilová, Lucie, Muchová, Petra, Čubáková, Miroslav, Kloz, Jakub, Švenda, Libor, Vítek, Petr, Klán
Publikováno v:
The Journal of organic chemistry. 87(5)
Bilirubin (BR) is an essential metabolite formed by the catabolism of heme. Phototherapy with blue-green light can be applied to reduce high concentrations of BR in blood and is used especially in the neonatal period. In this work, we studied the pho