Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Lucie Marešová"'
Autor:
Lucie Marešová, Marie Třešlová
Publikováno v:
Psychology and its Contexts, Vol 8, Iss 1, Pp 55-65 (2017)
This paper deals with the stressful situations in the profession of the nursing staff. The occupation of the nurse belongs to the most demanding ones. In this occupation, the nurse is permanently affected by many stressors of different types. She fac
Externí odkaz:
https://doaj.org/article/6b6c22728416424493ea849844a4510a
Publikováno v:
Photonic and Phononic Properties of Engineered Nanostructures XIII.
Autor:
Adrian Leontovyč, Lenka Ulrychová, Anthony J O'Donoghue, Jiří Vondrášek, Lucie Marešová, Martin Hubálek, Pavla Fajtová, Marta Chanová, Zhenze Jiang, Charles S Craik, Conor R Caffrey, Michael Mareš, Jan Dvořák, Martin Horn
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006446 (2018)
BACKGROUND:Serine proteases are important virulence factors for many pathogens. Recently, we discovered a group of trypsin-like serine proteases with domain organization unique to flatworm parasites and containing a thrombospondin type 1 repeat (TSR-
Externí odkaz:
https://doaj.org/article/fd9a30c7310c4f6b87532160c1ad348f
Autor:
Ora Schueler-Furman, Martin Horn, Jiří Brynda, Jiří Vondrášek, Nawsad Alam, Petr Kopáček, Iva Hánová, Michael Mareš, Radka Houštecká, Daniel Sojka, Lucie Marešová
Publikováno v:
Cell chemical biology. 25(3)
Summary Pepsin-family aspartic peptidases are biosynthesized as inactive zymogens in which the propeptide blocks the active site until its proteolytic removal upon enzyme activation. Here, we describe a novel dual regulatory function for the propepti
Autor:
Anthony J. O’Donoghue, Marta Chanová, Pavla Fajtová, Jiří Vondrášek, Martin Hubálek, Zhenze Jiang, Martin Horn, Lucie Marešová, Jan Dvořák, Adrian Leontovyč, Conor R. Caffrey, Michael Mareš, Charles S. Craik, Lenka Ulrychová
Publikováno v:
PLoS neglected tropical diseases, vol 12, iss 4
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006446 (2018)
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 12, Iss 4, p e0006446 (2018)
PLoS Neglected Tropical Diseases
Background Serine proteases are important virulence factors for many pathogens. Recently, we discovered a group of trypsin-like serine proteases with domain organization unique to flatworm parasites and containing a thrombospondin type 1 repeat (TSR-
Publikováno v:
Biochemistry. 45:15474-15482
Propeptide blocks the active site in the inactive zymogen of cathepsin D and is cleaved off during zymogen activation. We have designed a set of peptidic fragments derived from the propeptide structure and evaluated their inhibitory potency against m
Autor:
Pavla Fajtová, Lucie Marešová, Jiří Vondrášek, James H. McKerrow, Adéla Jílková, Pavlína Řezáčová, Jiří Brynda, Martin Horn, Michael Mareš, Conor R. Caffrey
Publikováno v:
Structure (London, England : 1993). 22(12)
SummaryCathepsin B1 (SmCB1) is a digestive protease of the parasitic blood fluke Schistosoma mansoni and a drug target for the treatment of schistosomiasis, a disease that afflicts over 200 million people. SmCB1 is synthesized as an inactive zymogen
Publikováno v:
Virology. 280:211-220
Immunogenicity of Varicella-zoster virus glycoproteins gE, gB, gH, and gL expressed by recombinant vaccinia viruses (VV) separately or simultaneously was determined in mice and guinea pigs by ELISA, Western blotting, radioimmunoprecipitation, plaque
Autor:
Viera Ludvíková, Jaroslav Brouček, Lucie Marešová, Šárka Němečková, L. Kutinová, Vladimír Vonka, Petr Hainz
Publikováno v:
Journal of General Virology. 80:2901-2908
It has been shown recently that the residual virulence of vaccinia virus (VV) is an important factor that influences the outcome of immunization with VV recombinants. This study focused on the correlation of the residual virulence of several VV recom
Publikováno v:
ACS chemical biology. 6(6)
Blood flukes of the genus Schistosoma cause the disease schistosomiasis that infects over 200 million people worldwide. Treatment relies on just one drug, and new therapies are needed should drug resistance emerge. Schistosoma mansoni cathepsin B1 (S