Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Lucie Cohen"'
Publikováno v:
Nature. 395:292-296
The transcription factor NF-kappaB coordinates the activation of numerous genes in response to pathogens and pro-inflammatory cytokines, and is, therefore, vital in the development of acute and chronic inflammatory diseases. NF-kappaB is activated by
Autor:
Y Y Chen, Roberta M. Kato, Randolph N. Mohr, D. Dorin, Fuyuhiko Tamanoi, Daniel E. H. Afar, Andrei Goga, Lucie Cohen, Naomi Rosenberg, M Huang
Publikováno v:
Proceedings of the National Academy of Sciences. 91:12448-12452
We report the characterization of a member of the ras gene family that is overexpressed in cells transformed by abl tyrosine kinase oncogenes. The gene, named kir (for kinase-inducible ras-like), is induced at the transcriptional level. kir mRNA has
Autor:
Lucie Cohen, John Hiscott
Publikováno v:
Journal of Cellular Physiology. 152:10-18
The NF-kappa B family of transcription proteins represents multiple DNA binding, rel related polypeptides that contribute to regulation of genes involved in immune responsiveness and inflammation, as well as activation of the HIV long terminal repeat
Autor:
Charles L. Sawyers, Randolph N. Mohr, Lucie Cohen, Andrei Goga, Jami McLaughlin, Daniel E. H. Afar, Owen N. Witte
Publikováno v:
Gene Technology ISBN: 9783642647048
Human chronic myelogenous leukemia (CML) is a cancer that is associated with a specific cytogenetic marker known as the Philadelphia (Ph1) chromosome (Nowell and Hungerford, 1960; Rowley, 1973; reviewed in Kurzrock et al. , 1988). Cells of multiple l
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e24acc5b5f99c7337cb178cff3984ad0
https://doi.org/10.1007/978-3-642-61122-3_18
https://doi.org/10.1007/978-3-642-61122-3_18
Autor:
Randolph N. Mohr, David A. Largaespada, Satoshi Tsukada, Lucie Cohen, Douglas C. Saffran, Maureen C. Howard, J. Fernando Bazan, Owen N. Witte, Nancy A. Jenkins, David J. Rawlings, J. Christopher Grimaldi, Neal G. Copeland
Publikováno v:
Science (New York, N.Y.). 261(5119)
The cytoplasmic tyrosine kinase, Bruton's tyrosine kinase (Btk, formerly bpk or atk), is crucial for B cell development. Loss of kinase activity results in the human immunodeficiency, X-linked agammaglobulinemia, characterized by a failure to produce
Characterization of TH3, an induction-specific protein interacting with the interferon beta promoter
Autor:
John Hiscott, Lucie Cohen
Publikováno v:
Virology. 191(2)
We report the purification and characterization of a unique DNA-binding protein termed TH3 that interacts with the positive regulatory domain (PRD) I and PRDIII domains of the interferon (IFN) R promoter. In cells treated with poly rI:rC and cyclohex
Publikováno v:
Virology. 184(2)
The effect of constitutive Tax expression on the interaction of NF-kappa B with its recognition sequence and on NF-kappa B-dependent gene expression was examined in T lymphoid Jurkat cell lines (19D and 9J) stably transformed with a Tax expression ve