Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Lucie Cechakova"'
Publikováno v:
Cancer Genomics Proteomics
Background Autophagy is a crucial factor contributing to radioresistance during radiotherapy. Although Lys05 has proven its ability to improve the results of radiotherapy through the inhibition of autophagy, molecular mechanisms of this inhibition re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13028693aaf0e3d7f07ad8d38975c67f
https://doi.org/10.21873/cgp.20196
https://doi.org/10.21873/cgp.20196
Publikováno v:
Military Medical Science Letters. 88:106-114
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f438a3aed1c3c2fe5bd028e7c1d2cb6c
https://doi.org/10.31482/mmsl.2019.007
https://doi.org/10.31482/mmsl.2019.007
Autor:
Kamila Ďurišová, Zuzana Šinkorová, Jiřina Vávrová, Petr Jost, Lucie Cechakova, Aleš Tichý, Jaroslav Pejchal, Martin Ondrej, Adela Kmochova
Publikováno v:
Journal of Applied Biomedicine. 16:66-74
The aim of this study was to compare the effects of DNA repair inhibitors in the context of radio-sensitization of human lung cells. The radio-sensitizing effects of NU7441 (1 mM), an inhibitor of DNA-dependent protein kinase (DNA-PK); KU55933 (10 μ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1f85cd9acd23ecafc7042baec1a27e29
https://doi.org/10.1016/j.jab.2017.10.008
https://doi.org/10.1016/j.jab.2017.10.008
Autor:
Vojtech Pavlik, Martin Ondrej, Ravi K. Amaravadi, Petr Jost, Dana Cizkova, Jaroslav Pejchal, Ales Bezrouk, Ales Tichy, Jeffrey D. Winkler, Lucie Cechakova
Publikováno v:
International Journal of Molecular Sciences
Volume 20
Issue 23
Volume 20
Issue 23
Autophagy inhibition through small-molecule inhibitors is one of the approaches to increase the efficiency of radiotherapy in oncological patients. A new inhibitor&mdash
Lys05&mdash
with the potential to accumulate within lysosomes and to b
Lys05&mdash
with the potential to accumulate within lysosomes and to b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8d1a0a91571f4eb9dcd6f66cb5d952a
http://europepmc.org/articles/PMC6928878
http://europepmc.org/articles/PMC6928878
Autor:
Aleš Tichý, Ivo Fabrik, Marek Link, Radana Karlíková, Hana Janečková, Martin Ondrej, Barbora Salovska, Lucie Cechakova, David Friedecký
Publikováno v:
PLoS ONE
PLoS ONE, Vol 13, Iss 7, p e0199349 (2018)
PLoS ONE, Vol 13, Iss 7, p e0199349 (2018)
Current anti-cancer strategy takes advantage of tumour specific abnormalities in DNA damage response to radio- or chemo-therapy. Inhibition of the ATR/Chk1 pathway has been shown to be synthetically lethal in cells with high levels of oncogene-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f44d1af81897338587867e8e380d265
http://europepmc.org/articles/PMC6042708
http://europepmc.org/articles/PMC6042708
Autor:
Klara Kubelkova, Kamila Durisova, Marketa Nemcova, Jaroslav Pejchal, Martin Ondrej, Jan Bures, Adela Kmochova, Ilja Tachecí, Ales Tichy, Anna Lierová, Sarka Pruchova, Kamil Kuca, Zuzana Šinkorová, Ilona Fatorova, Jirina Vavrova, Lucie Cechakova
Publikováno v:
Radiation research. 186(3)
We examined the effect of epidermal growth factor (EGF) treatment in mice that received bone marrow transplantation (BMT) after 11 Gy whole-body irradiation. C57Bl/6 mice were divided into three treatment groups: 0 Gy; 11 Gy ((60)Co, single dose, 0.5
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5270bc8e848b511a2b69f7e8b652050
https://pubmed.ncbi.nlm.nih.gov/27538113
https://pubmed.ncbi.nlm.nih.gov/27538113
Autor:
Lucie Cechakova
Publikováno v:
SGEM International Multidisciplinary Scientific GeoConference EXPO Proceedings.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ecab40a667978a863610a63452f5551
https://doi.org/10.5593/sgem2012/s20.v5037
https://doi.org/10.5593/sgem2012/s20.v5037
Autor:
Barbora Šalovská, Hana Janečková, Ivo Fabrik, Radana Karlíková, Lucie Čecháková, Martin Ondrej, Marek Link, David Friedecký, Aleš Tichý
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199349 (2018)
Current anti-cancer strategy takes advantage of tumour specific abnormalities in DNA damage response to radio- or chemo-therapy. Inhibition of the ATR/Chk1 pathway has been shown to be synthetically lethal in cells with high levels of oncogene-induce
Externí odkaz:
https://doaj.org/article/b33611cc1f7e4cc3ba499710b069781a
Publikováno v:
Radiotherapy and Oncology. (2):265-275
Radiation-induced autophagy is believed to represent a radioprotective mechanism of cancer cells. Thus, its inhibition should support radiation treatment and increase its efficacy. On the other hand, there is evidence that radiation alone or in combi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00a85ef9ab29c0391dc89f4311488ddf