Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Lucie Carrié"'
Autor:
Moritz Meyer-Jens, Kristin Wenzel, Karina Grube, Julia Rüdebusch, Elisabeth Krämer, Martin Bahls, Kilian Müller, Hannah Voß, Hartmut Schlüter, Stephan B. Felix, Lucie Carrier, Stephanie Könemann, Saskia Schlossarek
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 7, Iss , Pp 100059- (2024)
Sacubitril/valsartan (Sac/Val) belongs to the group of angiotensin receptor–neprilysin inhibitors and has been used for the treatment of heart failure (HF) for several years. The mechanisms that mediate the beneficial effects of Sac/Val are not yet
Externí odkaz:
https://doaj.org/article/d2ef4d241de746f5a3ef0a5e68bc9de6
Autor:
Oumaima Laghzali, MSc, Shahriar Shalikar, MSc, Siqin Liu, MSc, Joao dos Santos Periquito, PhD, Andreas Pohlmann, PhD, Frank Kober, PhD, Lucie Carrier, PhD, Thoralf Niendorf, Sonia Waiczies, PhD, Min-Chi Ku, PhD
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 26, Iss , Pp 100969- (2024)
Externí odkaz:
https://doaj.org/article/21d2b1937c2b4ecd8688bd52e88c2c2e
Autor:
Edgar E. Nollet, Sila Algül, Max Goebel, Saskia Schlossarek, Nicole N. van der Wel, Judith J.M. Jans, Mark A. van de Wiel, Jaco C. Knol, Thang V. Pham, Sander R. Piersma, Richard de Goeij-de Haas, Jill Hermans, Jan Bert van Klinken, Michel van Weeghel, Riekelt H. Houtkooper, Lucie Carrier, Connie R. Jimenez, Diederik W.D. Kuster, Jolanda van der Velden
Publikováno v:
Journal of Molecular and Cellular Cardiology Plus, Vol 6, Iss , Pp 100050- (2023)
Background and aim: Phenotypic expression of hypertrophic cardiomyopathy (HCM) and disease course are associated with unfavorable metabolic health. We investigated if Western diet (WD) feeding is sufficient to trigger cardiac hypertrophy and dysfunct
Externí odkaz:
https://doaj.org/article/a35423357cb242d7a31ba3d7bed60292
Autor:
Niels Pietsch, Jiancheng Cheng, Antonietta Fazio, Leonie Ewald, Erda Alizoti, Elisabeth Krämer, Ellen Orthey, Lucie Carrier, Sonia R Singh
Publikováno v:
Stem Cell Research, Vol 71, Iss , Pp 103188- (2023)
Variants in CRYAB can lead to desmin-related (cardio-)myopathy (DRM), a genetic muscle disorder with no curative treatment available. We introduced a homozygous CRYAB c.358G > A (p.Arg120Gly) mutation, which is established for the study of DRM in mic
Externí odkaz:
https://doaj.org/article/690b5a4cbefd4b42b1db8d1852a43c94
Autor:
Daniel T. Utzschneider, Amandine Legat, Silvia A. Fuertes Marraco, Daniel E. Speiser, Lucie Carrié, Dietmar Zehn, Immanuel F. Luescher
Publikováno v:
Nature immunology
During chronic infection, pathogen-specific CD8(+) T cells upregulate expression of molecules such as the inhibitory surface receptor PD-1, have diminished cytokine production and are thought to undergo terminal differentiation into exhausted cells.
Disease modeling of a mutation in α‐actinin 2 guides clinical therapy in hypertrophic cardiomyopathy
Autor:
Maksymilian Prondzynski, Marc D Lemoine, Antonia TL Zech, András Horváth, Vittoria Di Mauro, Jussi T Koivumäki, Nico Kresin, Josefine Busch, Tobias Krause, Elisabeth Krämer, Saskia Schlossarek, Michael Spohn, Felix W Friedrich, Julia Münch, Sandra D Laufer, Charles Redwood, Alexander E Volk, Arne Hansen, Giulia Mearini, Daniele Catalucci, Christian Meyer, Torsten Christ, Monica Patten, Thomas Eschenhagen, Lucie Carrier
Publikováno v:
EMBO Molecular Medicine, Vol 14, Iss 8, Pp n/a-n/a (2022)
Externí odkaz:
https://doaj.org/article/20088ae3e8874325a43b88d720c8d7fd
Autor:
Min-Chi Ku, Frank Kober, Yi-Ching Lai, Andreas Pohlmann, Fatimunnisa Qadri, Michael Bader, Lucie Carrier, Thoralf Niendorf
Publikováno v:
Journal of Cardiovascular Magnetic Resonance, Vol 23, Iss 1, Pp 1-13 (2021)
Abstract Background Hypertrophic cardiomyopathy (HCM) related myocardial vascular remodelling may lead to the reduction of myocardial blood supply and a subsequent progressive loss of cardiac function. This process has been difficult to observe and t
Externí odkaz:
https://doaj.org/article/e03c11be46e0404b8684de5964ee7cdb
Publikováno v:
The Journal of experimental medicine
Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 209, no. 10, pp. 1769-1779
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 209, No 10 (2012) pp. 1769-79
Journal of Experimental Medicine
Journal of Experimental Medicine, vol. 209, no. 10, pp. 1769-1779
The Journal of Experimental Medicine
Journal of Experimental Medicine, Vol. 209, No 10 (2012) pp. 1769-79
Autoimmunity occurs because central and peripheral tolerance mechanisms fail to tolerize T cells with weak self-reactivity to tissue-restricted antigen.
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8+ T
Central and peripheral tolerance prevent autoimmunity by deleting the most aggressive CD8+ T
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa7db3bc3cecf0a23fb2580ed43a798b
http://resolver.sub.uni-goettingen.de/purl?gs-1/10626
http://resolver.sub.uni-goettingen.de/purl?gs-1/10626
Autor:
Nele Warnecke, Bärbel M. Ulmer, Sandra D. Laufer, Aya Shibamiya, Elisabeth Krämer, Christiane Neuber, Sophia Hanke, Charlotta Behrens, Malte Loos, Julia Münch, Jirko Kühnisch, Sabine Klaassen, Thomas Eschenhagen, Monica Patten-Hamel, Lucie Carrier, Giulia Mearini
Publikováno v:
Stem Cell Research, Vol 55, Iss , Pp 102489- (2021)
MYBPC3 is the most frequently affected gene in hypertrophic cardiomyopathy (HCM), which is an autosomal-dominant cardiac disease caused by mutations in sarcomeric proteins. Bi-allelic truncating MYBPC3 mutations are associated with severe forms of ne
Externí odkaz:
https://doaj.org/article/823c7120cb5b4e818f122df69c905bed
Autor:
Antonia T. L. Zech, Maksymilian Prondzynski, Sonia R. Singh, Niels Pietsch, Ellen Orthey, Erda Alizoti, Josefine Busch, Alexandra Madsen, Charlotta S. Behrens, Moritz Meyer-Jens, Giulia Mearini, Marc D. Lemoine, Elisabeth Krämer, Diogo Mosqueira, Sanamjeet Virdi, Daniela Indenbirken, Maren Depke, Manuela Gesell Salazar, Uwe Völker, Ingke Braren, William T. Pu, Thomas Eschenhagen, Elke Hammer, Saskia Schlossarek, Lucie Carrier
Publikováno v:
Cells, Vol 11, Iss 17, p 2745 (2022)
Genetic variants in α-actinin-2 (ACTN2) are associated with several forms of (cardio)myopathy. We previously reported a heterozygous missense (c.740C>T) ACTN2 gene variant, associated with hypertrophic cardiomyopathy, and characterized by an electro
Externí odkaz:
https://doaj.org/article/109fa3ab16674cf981367758f4aa3eb1