Výsledky vyhledávání - "Lucie Balonova"

Utilization of a tetracycline-inducible system for high-level expression of recombinant proteins in Francisella tularensis LVS

Autor: Valeria Sheshko, Marek Link, Lucie Balonova, Igor Golovliov, Jiri Stulik

Publikováno v: Plasmid. 115:102564

Francisella tularensis is a Gram-negative intracellular pathogen causing tularemia. A number of its potential virulence factors have been identified, but their biology and functions are not precisely known. Understanding the biological and immunologi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfc1c4f8c0495f45051afc25ccc46e94
https://doi.org/10.1016/j.plasmid.2021.102564

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Characterization of Tetratricopeptide Repeat-Like Proteins in Francisella tularensis and Identification of a Novel Locus Required for Virulence

Autor: Sherry Mou, Joel A. Bozue, Adela Straskova, Todd K. Kijek, Petra Spidlova, Jiri Stulik, Vera Dankova, Lucie Balonova, Lukas Cerveny, Barbora Szotáková, Patricia L. Worsham, Christopher K. Cote, Daniela Putzova

Publikováno v: Infection and Immunity. 82:5035-5048

Francisella tularensis is a highly infectious bacterium that causes the potentially lethal disease tularemia. This extremely virulent bacterium is able to replicate in the cytosolic compartments of infected macrophages. To invade macrophages and to c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eed05a170d34a273c1e88e21995fdabf
https://doi.org/10.1128/iai.01620-14

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Inactivation of Francisella tularensis Gene Encoding Putative ABC Transporter Has a Pleiotropic Effect upon Production of Various Glycoconjugates

Autor: Adela Straskova, Valeria Sheshko, Lucie Balonova, Vera Dankova, Jiri Stulik, Marek Link

Publikováno v: Journal of proteome research. 15(2)

Francisella tularensis, an intracellular pathogen causing the disease tularemia, utilizes surface glycoconjugates such as lipopolysaccharide, capsule, and capsule-like complex for its protection against inhospitable conditions of the environment. Fra

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ecb5edc90206185729d602b25ac4e407
https://pubmed.ncbi.nlm.nih.gov/26815358

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Specific antibodies protect gamma-irradiated mice against Francisella tularensis infection

Autor: Ales Macela, Jiri Stulik, Lucie Balonova, Klara Kubelkova, Jaroslav Pejchal, Zuzana Krocova

Publikováno v: Microbial Pathogenesis. 53:259-268

The role of antibodies in the course of Francisella tularensis (F. tularensis) infection is still a subject of debate. The understanding of the poorly described role of humoral immunity is more than important for the effort to develop effective proph

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b330b468e1ce0224606ad117b6913d33
https://doi.org/10.1016/j.micpath.2012.07.006

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Characterization of protein glycosylation in Francisella tularensis subsp. holarctica: identification of a novel glycosylated lipoprotein required for virulence

Autor: Lucie, Balonova, Benjamin F, Mann, Lukas, Cerveny, William R, Alley, Eva, Chovancova, Anna-Lena, Forslund, Emelie N, Salomonsson, Ake, Forsberg, Jiri, Damborsky, Milos V, Novotny, Lenka, Hernychova, Jiri, Stulik

Publikováno v: Molecularcellular proteomics : MCP. 11(7)

FTH_0069 is a previously uncharacterized strongly immunoreactive protein that has been proposed to be a novel virulence factor in Francisella tularensis. Here, the glycan structure modifying two C-terminal peptides of FTH_0069 was identified utilizin

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a1c6a136e0f41becf75933372ed6e9f
https://pubmed.ncbi.nlm.nih.gov/22361235

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Use of magnetic hydrazide-modified polymer microspheres for enrichment of Francisella tularensis glycoproteins

Autor: Lucie Balonova, Jiří Stulík, Milos V. Novotny, Daniel Horák, Lenka Hernychová, Benjamin F. Mann, Zdeněk Plichta

The field of microbial proteomics has currently experienced a boom in the discovery of glycosylated proteins of various pathogenic bacteria as potential mediators of host–pathogen interactions. The presence of glycoproteins has recently been discov

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::978c95da5672eae4c4f78b5f0421b0b7
https://europepmc.org/articles/PMC4966525/

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Multimethodological approach to identification of glycoproteins from the proteome of Francisella tularensis, an intracellular microorganism

Autor: Marek Link, Benjamin F. Mann, Milos V. Novotny, Zuzana Bílková, Lenka Hernychová, Jiri Stulik, Lucie Balonova

Publikováno v: Journal of proteome research. 9(4)

It appears that most glycoproteins found in pathogenic bacteria are associated with virulence. Despite the recent identification of novel virulence factors, the mechanisms of virulence in Francisella tularensis are poorly understood. In spite of its

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f1f773a59e0c9241999af5583873300
https://pubmed.ncbi.nlm.nih.gov/20175567

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