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PAK3 controls the tangential to radial migration switch of cortical interneurons by coordinating changes in cell shape and polarity

Autor: Jean-Vianney Barnier, Robert S. Adelstein, Justine Masson, Lucie Viou, Pierre Launay, Véronique Rousseau, Zhengping Jia, Clarisse Pace, Fujio Murakami, Xuefei Ma, Christine Métin

SUMMARYDuring the embryonic development, cortical interneurons migrate a long distance tangentially and then re-orient radially to settle in the cortical plate where they contribute to cortical circuits. Migrating interneurons express PAK3, a p21-act

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::49ebd9e4af920fe21585ee98fe0ae6fb
https://doi.org/10.1101/2020.07.06.168179

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Sugar Beet Production in France

Autor: Mohamed F. R. Khan, Lucie Viou, Stéphanie Heno

Publikováno v: Sugar Tech. 20:392-395

France was one of the earliest countries to grow sugar beet, and in 2016, it produced 382,858 ha in 10 of its northern regions to supply sugar and ethanol/alcohol. France is a top producer of sugar beet with average of over 88 tonnes of root yield ha

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d6c61ab68dad6d5c961abbd679e461cd
https://doi.org/10.1007/s12355-017-0575-x

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N-Cadherin Sustains Motility and Polarity of Future Cortical Interneurons during Tangential Migration

Autor: Laetitia Hennekinne, René-Marc Mège, Robert S. Adelstein, Fujio Murakami, Mitsutoshi Yanagida, Lucie Viou, Christine Métin, Xufei Ma, Nicoletta Kessaris, Camilla Luccardini

Publikováno v: The Journal of Neuroscience. 33:18149-18160

In the developing brain, cortical GABAergic interneurons migrate long distances from the medial ganglionic eminence (MGE) in which they are generated, to the cortex in which they settle. MGE cells express the cell adhesion molecule N-cadherin, a homo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcbee7dc22bc9d789a970e167b8aaca
https://doi.org/10.1523/jneurosci.0593-13.2013

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Cortical interneurons migrating on a pure substrate of N-cadherin exhibit fast synchronous centrosomal and nuclear movements and reduced ciliogenesis

Autor: Camilla, Luccardini, Claire, Leclech, Lucie, Viou, Jean-Paul, Rio, Christine, Métin

Publikováno v: Frontiers in Cellular Neuroscience

The embryonic development of the cortex involves a phase of long distance migration of interneurons born in the basal telencephalon. Interneurons first migrate tangentially and then reorient their trajectories radially to enter the developing cortex.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::b6ba025df3d673dd37df37cb149ff215
https://pubmed.ncbi.nlm.nih.gov/26283922

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Tangentially migrating neurons assemble a primary cilium that promotes their reorientation to the cortical plate

Autor: Camilla Luccardini, Lucie Viou, Theano Irinopoulou, Nathalie Spassky, Jean-Pierre Lechaire, Sergio Espeso Gil, Vera Kiyasova, Thomas Boudier, J.P. Rio, Nicoletta Kessaris, Pierre-Serge Launay, Christine Métin, Chantal Alvarez, Jean-Pierre Baudoin

Publikováno v: Neuron
Neuron, 2012, 76 (6), pp.1108-1122. ⟨10.1016/j.neuron.2012.10.027⟩
Neuron, Elsevier, 2012, 76 (6), pp.1108-1122. ⟨10.1016/j.neuron.2012.10.027⟩

International audience; In migrating neurons, the centrosome nucleates and anchors a polarized network of microtubules that directs organelle movements. We report here that the mother centriole of neurons migrating tangentially from the medial gangli

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7cbd67918e900945716d2e12da5d65f
https://pubmed.ncbi.nlm.nih.gov/23259947

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8Cl-cAMP modifies the balance between PKAR1 and PKAR2 and modulates the cell cycle, growth and apoptosis in human adrenocortical H295R cells

Autor: Z. Bouizar, Jérôme Bertherat, Lucie Viou, Marthe Rizk-Rabin, Bruno Ragazzon, Mariuccia Hortane

Publikováno v: Journal of Molecular Endocrinology
Journal of Molecular Endocrinology, 2010, 44 (6), pp.331-347. ⟨10.1677/JME-09-0120⟩
Journal of Molecular Endocrinology, BioScientifica, 2010, 44 (6), pp.331-347. ⟨10.1677/JME-09-0120⟩

Various types of protein kinase A (PKA) alterations have been observed in adrenocortical tumours and Carney complex (CNC). PKA is a heterotetramer of two regulatory and two catalytic subunits. The R1A and R2B proteins are the most abundant regulatory

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::779558fe8e475348baf0f113077e2988
https://hal.science/hal-02376050

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