Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Lucie, Rárová"'
Autor:
Aneta M. Tomkiel, Dorota Czajkowska-Szczykowska, Ewa Olchowik-Grabarek, Lucie Rárová, Szymon Sękowski, Jacek W. Morzycki
Publikováno v:
Molecules, Vol 28, Iss 1, p 189 (2022)
A chemoselective procedure for MCPBA oxidation of 26-thiodiosgenin to corresponding sulfoxides and sulfone was elaborated. An unusual equilibration of sulfoxides in solution was observed. Moreover, α-alkylation of sulfoxide and sulfone was investiga
Externí odkaz:
https://doaj.org/article/0bb294829429486689e2c90a20f2df42
Publikováno v:
Plants, Vol 10, Iss 10, p 2082 (2021)
Background: Oleanolic acid is a natural plant adaptogen, and tryptamine is a natural psychoactive drug. To compare their effects of with the effect of their derivatives, tryptamine and fluorotryptamine amides of oleanolic acid were designed and synth
Externí odkaz:
https://doaj.org/article/a577956f3a4f447c90fdbe128ac2fa47
Autor:
Zulal Özdemir, Uladzimir Bildziukevich, Martina Čapková, Petra Lovecká, Lucie Rárová, David Šaman, Michala Zgarbová, Barbora Lapuníková, Jan Weber, Oxana Kazakova, Zdeněk Wimmer
Publikováno v:
Biomedicines, Vol 9, Iss 8, p 951 (2021)
(1) Background: To compare the effect of selected triterpenoids with their structurally resembling derivatives, designing of the molecular ribbons was targeted to develop compounds with selectivity in their pharmacological effects. (2) Methods: In th
Externí odkaz:
https://doaj.org/article/2a5e73deb0554ae48aca238727c9dc18
Publikováno v:
Processes; Volume 11; Issue 6; Pages: 1860
α-Tocopheryl succinate (α-TS) and α-tocopheryloxyacetic acid (α-TEA) are potent inducers of apoptosis in cancer cells and efficient suppressors of tumors in experimental model cancer cell lines. They exhibit selective cytotoxicity against tumor c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::4b682e6f4e9449ff2333637836520e1b
Autor:
Uladzimir Bildziukevich, Zulal Özdemir, David Šaman, Martin Vlk, Miroslav Šlouf, Lucie Rárová, Zdeněk Wimmer
Publikováno v:
Organic & Biomolecular Chemistry. 20:8157-8163
Novel 1,10-phenanthroline–triterpenoid amphiphiles formed nano-assemblies in water, coordinated Cu(ii) and 64Cu(ii) salts for potential cancer monitoring and therapy, and displayed cytotoxicity partly dependent on the formation of nano-assemblies.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0d353c634a0594f485552cfb0532ec8c
https://doi.org/10.1039/d2ob01172g
https://doi.org/10.1039/d2ob01172g
Autor:
Mohamed A. Tammam, Lucie Rárová, Marie Kvasnicová, Gabriel Gonzalez, Ahmed M. Emam, Aldoushy Mahdy, Miroslav Strnad, Efstathia Ioannou, Vassilios Roussis
Publikováno v:
Marine Drugs, Vol 18, Iss 12, p 632 (2020)
Six new (1, 2, 6, 8, 13, and 20) and twenty previously isolated (3–5, 7, 9–12, 14–19, and 21–26) steroids featuring thirteen different carbocycle motifs were isolated from the organic extract of the soft coral Sinularia polydactyla collected
Externí odkaz:
https://doaj.org/article/502c5988787d4ac1af682ef9c9cfe69d
Publikováno v:
Molecules, Vol 25, Iss 15, p 3546 (2020)
The target diosgenin–betulinic acid conjugates are reported to investigate their ability to enhance and modify the pharmacological effects of their components. The detailed synthetic procedure that includes copper(I)-catalyzed Huisgen 1,3-dipolar c
Externí odkaz:
https://doaj.org/article/298d8c74d09c43299216ff2d3fda961f
Autor:
Barbara Seroka, Zenon Łotowski, Agnieszka Hryniewicka, Lucie Rárová, Rafal R. Sicinski, Aneta M. Tomkiel, Jacek W. Morzycki
Publikováno v:
Molecules, Vol 25, Iss 3, p 655 (2020)
A series of bile acid derived 1,2- and 1,3-diamines as well as their platinum(II) complexes were designed and synthesized in hope to get a highly cytotoxic compound by the combination of two bioactive moieties. All complexes obtained were subjected t
Externí odkaz:
https://doaj.org/article/ced0752183f4482ea6ce97e0506049c8
Autor:
Strahinja Kovačević, Milica Karadžić Banjac, Sanja Podunavac-Kuzmanović, Jovana Ajduković, Benjamin Salaković, Lucie Rárová, Miloš Đorđević, Mirjana Ivanov
Publikováno v:
Journal of Molecular Structure. 1283:135272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c283fd29c7e372ef170165cef87c03f
https://doi.org/10.1016/j.molstruc.2023.135272
https://doi.org/10.1016/j.molstruc.2023.135272
Autor:
Markéta Pazderková, Lucie Rárová, Nonappa, Manu Lahtinen, David Šaman, Lucie Bednárová, Kia Bertula, Zdeněk Wimmer, Zülal Özdemir
Publikováno v:
Langmuir. 37:2693-2706
Natural and abundant plant triterpenoids are attractive starting materials for the synthesis of conformationally rigid and chiral building blocks for functional soft materials. Here, we report the rational design of three oleanolic acid-triazole-sper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c518beb4307ad07dd1f2630d7ab7693f
https://doi.org/10.1021/acs.langmuir.0c03335
https://doi.org/10.1021/acs.langmuir.0c03335