Coxsackievirus infection induces direct pancreatic β cell killing but poor antiviral CD8 ⁺ T cell responses.

Autor: Vecchio F; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Carré A; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Korenkov D; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Zhou Z; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Apaolaza P; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Tuomela S; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden., Burgos-Morales O; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Snowhite I; Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA.; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Perez-Hernandez J; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Brandao B; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Afonso G; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Halliez C; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France., Kaddis J; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA.; Department of Diabetes and Cancer Discovery Science, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Kent SC; Diabetes Center of Excellence, Department of Medicine, University of Massachusetts Medical Chan School, Worcester, MA, USA., Nakayama M; Barbara Davis Center for Diabetes, University of Colorado School of Medicine, Aurora, CO, USA., Richardson SJ; Islet Biology Exeter (IBEx), Exeter Centre of Excellence for Diabetes Research (EXCEED), Department of Clinical and Biomedical Sciences, University of Exeter Medical School, Exeter, UK., Vinh J; ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France., Verdier Y; ESPCI Paris, PSL University, Spectrométrie de Masse Biologique et Protéomique, CNRS UMR8249, Paris, France., Laiho J; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland., Scharfmann R; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France., Solimena M; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Paul Langerhans Institute Dresden (PLID), Helmholtz Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany., Marinicova Z; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany.; Paul Langerhans Institute Dresden (PLID), Helmholtz Munich, University Hospital and Faculty of Medicine, TU Dresden, Dresden, Germany., Bismuth E; Assistance Publique Hôpitaux de Paris, Service d'Endocrinologie Pédiatrique, Robert Debré Hospital, Paris, France., Lucidarme N; Assistance Publique Hôpitaux de Paris, Service de Pédiatrie, Jean Verdier Hospital, Bondy, France., Sanchez J; Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., Bustamante C; Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., Gomez P; Department of Pediatrics, Division of Pediatric Endocrinology, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA., Buus S; Department of Immunology and Microbiology, Faculty of Health Sciences, University of Copenhagen, Copenhagen, Denmark., You S; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Indiana Biosciences Research Institute, Indianapolis, IN, USA., Pugliese A; Diabetes Research Institute, Leonard Miller School of Medicine, University of Miami, Miami, FL, USA.; Department of Diabetes Immunology, Arthur Riggs Diabetes and Metabolism Research Institute, Beckman Research Institute, City of Hope, Duarte, CA, USA., Hyoty H; Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.; Fimlab Laboratories, Tampere, Finland.; Department of Pediatrics, Tampere University Hospital, Tampere, Finland., Rodriguez-Calvo T; Institute of Diabetes Research, Helmholtz Zentrum München, German Research Center for Environmental Health, Munich-Neuherberg, Germany.; German Center for Diabetes Research (DZD e.V.), Neuherberg, Germany., Flodstrom-Tullberg M; Center for Infectious Medicine, Department of Medicine Huddinge, Karolinska Institutet, Karolinska University Hospital Huddinge, Stockholm, Sweden., Mallone R; Université Paris Cité, Institut Cochin, CNRS, INSERM, Paris, France.; Assistance Publique Hôpitaux de Paris, Service de Diabétologie et Immunologie Clinique, Cochin Hospital, Paris, France.; Indiana Biosciences Research Institute, Indianapolis, IN, USA.

Publikováno v: Science advances [Sci Adv] 2024 Mar 08; Vol. 10 (10), pp. eadl1122. Date of Electronic Publication: 2024 Mar 06.

INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes

Autor: Dunger, David B., Bruggraber, Sylvaine F. A., Mander, Adrian P., Marcovecchio, M. Loredana, Tree, Timothy, Chmura, Piotr Jaroslaw, Knip, Mikael, Schulte, Anke M., Mathieu, Chantal, Mathieu, C., Gillard, P., Casteels, K., Overbergh, L., Dunger, D., Wallace, C., Evans, M., Thankamony, A., Hendriks, E., Bruggraber, S., Peakman, M., Tree, T., Morgan, N., Richardson, S., Todd, J., Wicker, L., Mander, A., Dayan, C., Alhadj Ali, M., Pieber, T., Eizirik, D., Cnop, M., Brunak, S., Pociot, F., Johannesen, J., Rossing, P., Legido Quigley, C., Mallone, R., Scharfmann, R., Boitard, C., Knip, M., Otonkoski, T., Veijola, R., Lahesmaa, R., Oresic, M., Toppari, J., Danne, T., Ziegler, A. G., Achenbach, P., Rodriguez-Calvo, T., Solimena, M., Bonifacio, E., Speier, S., Holl, R., Dotta, F., Chiarelli, F., Marchetti, P., Bosi, E., Cianfarani, S., Ciampalini, P., de Beaufort, C., Dahl-Jørgensen, K., Skrivarhaug, T., Joner, G., Krogvold, L., Jarosz-Chobot, P., Battelino, T., Thorens, B., Gotthardt, M., Roep, B., Nikolic, T., Zaldumbide, A., Lernmark, A., Lundgren, M., Costecalde, G., Strube, T., Schulte, A., Nitsche, A., von Herrath, M., Wesley, J., Napolitano-Rosen, A., Thomas, M., Schloot, N., Goldfine, A., Waldron-Lynch, F., Kompa, J., Vedala, A., Hartmann, N., Nicolas, G., van Rampelbergh, J., Bovy, N., Dutta, S., Soderberg, J., Ahmed, S., Martin, F., Agiostratidou, G., Koralova, A., Willemsen, R., Smith, A., Anand, B., Puthi, V., Zac-Varghese, S., Datta, V., Dias, R., Sundaram, P., Vaidya, B., Patterson, C., Owen, K., Piel, B., Heller, S., Randell, T., Gazis, T., Bismuth Reismen, E., Carel, J-C, Riveline, J-P, Gautier, J-F, Andreelli, F., Travert, F., Cosson, E., Penfornis, A., Petit, C., Feve, B., Lucidarme, N., Beressi, J-P, Ajzenman, C., Radu, A., Greteau-Hamoumou, S., Bibal, C., Meissner, T., Heidtmann, B., Toni, S., Rami-Merhar, B., Eeckhout, B., Peene, B., Vantongerloo, N., Maes, T., Gommers, L., Marcovecchio, M.L., Vela, J., Latres, E.

Publikováno v: Dunger, D B, Bruggraber, S F A, Mander, A P, Marcovecchio, M L, Tree, T, Chmura, P J, Knip, M, Schulte, A M, Mathieu, C & INNODIA consortium 2022, ' INNODIA Master Protocol for the evaluation of investigational medicinal products in children, adolescents and adults with newly diagnosed type 1 diabetes ', Trials, vol. 23, no. 1, 414 . https://doi.org/10.1186/s13063-022-06259-z
Trials 23:414 (2022)

Background The INNODIA consortium has established a pan-European infrastructure using validated centres to prospectively evaluate clinical data from individuals with newly diagnosed type 1 diabetes combined with centralised collection of clinical sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204b8f8261c567ae6812c50bb5718aea
https://doi.org/10.1186/s13063-022-06259-z

Facteurs associés à l’acidocétose révélatrice du diabète de l’enfant et à sa sévérité

Autor: Blanc, N, Lucidarme, N, Tubiana-Rufi, N ^*

Publikováno v: In Archives de pédiatrie 2003 10(4):320-325

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Evidence for Molecular Mimicry between SARS‐CoV‐2 and Human Antigens: Implications for Autoimmunity in COVID‐19.

Autor: Arévalo-Cortés, Andrea¹ (AUTHOR) andrea.arevalo@unl.edu.ec, Rodriguez-Pinto, Daniel² (AUTHOR), Aguilar-Ayala, Leonardo² (AUTHOR), Mageed, Rizgar (AUTHOR)

Publikováno v: Autoimmune Diseases (2090-0422). 8/30/2024, Vol. 2024, p1-9. 9p.