Zobrazeno 1 - 10
of 224
pro vyhledávání: '"Luciano MAYOL"'
Autor:
Antonella Virgilio, Teresa Amato, Luigi Petraccone, Francesca Esposito, Nicole Grandi, Enzo Tramontano, Raquel Romero, Shozeb Haider, Isabel Gomez-Monterrey, Ettore Novellino, Luciano Mayol, Veronica Esposito, Aldo Galeone
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-9 (2018)
Abstract In this paper, we report our investigations on analogues of the anti-human immunodeficiency virus type 1 (HIV-1) integrase (IN) aptamer T30175 in which the individual thymidines forming the loops were replaced by 5-hydroxymethyl-2′-deoxyur
Externí odkaz:
https://doaj.org/article/a75cacdbf3dd4a539019f5c9a75a4920
Autor:
Roberto Barone, Lorenzo De Napoli, Luciano Mayol, Marina Paolucci, Maria Grazia Volpe, Luigi D’Elia, Antonino Pollio, Marco Guida, Edvige Gambino, Federica Carraturo, Roberta Marra, Francesco Vinale, Sheridan Lois Woo, Matteo Lorito
Publikováno v:
Marine Drugs, Vol 18, Iss 3, p 169 (2020)
Algae have multiple similarities with fungi, with both belonging to the Thallophyte, a polyphyletic group of non-mobile organisms grouped together on the basis of similar characteristics, but not sharing a common ancestor. The main difference between
Externí odkaz:
https://doaj.org/article/601e244aedc14ab4a4c7a470ced5dc5e
Autor:
Gennaro Piccialli, Luciano Mayol, Michela Varra, Giorgia Oliviero, Nicola Borbone, Jussara Amato, Vincenzo Piccialli, Stefano D'Errico
Publikováno v:
Molecules, Vol 18, Iss 8, Pp 9420-9431 (2013)
The antiviral activity of certain acyclic nucleosides drew our attention to the fact that the replacement of the furanose ring by an alkyl group bearing hydroxyl(s) could be a useful structural modification to modulate the biological properties of th
Externí odkaz:
https://doaj.org/article/ab6dabf88819438d9887bc66681e60a1
Autor:
Luciano Mayol, Vincenzo Piccialli, Daniele D'Alonzo, Jussara Amato, Nicola Borbone, Giorgia Oliviero, Stefano D'Errico, Gennaro Piccialli
Publikováno v:
Molecules, Vol 17, Iss 11, Pp 13036-13044 (2012)
The substitution of a hydroxyl group by a fluorine atom in a potential drug is an efficient reaction that can, in principle, improve its pharmacological properties. Herein, the synthesis of the novel compound 5′-fluoro-5′-deoxyacadesine (5′-F-A
Externí odkaz:
https://doaj.org/article/353d6913fbf94f87b8a2453f3052974b
Autor:
Gennaro Piccialli, Vincenzo Piccialli, Luciano Mayol, Michela Varra, Jussara Amato, Nicola Borbone, Giorgia Oliviero, Stefano D’Errico
Publikováno v:
Molecules, Vol 16, Iss 9, Pp 8110-8118 (2011)
The solid-phase synthesis of the first example of a new diphosphate AICAR derivative is reported. The new substance is characterized by the presence of a 5'-phosphate group while a second phosphate moiety is installed on a 5-hydroxypentyl chain attac
Externí odkaz:
https://doaj.org/article/bacbd6c54357465592d7e52b3bd5ba9f
Autor:
Stefano D’Errico, Nicola Borbone, Bruno Catalanotti, Agnese Secondo, Tiziana Petrozziello, Ilaria Piccialli, Anna Pannaccione, Valeria Costantino, Luciano Mayol, Gennaro Piccialli, Giorgia Oliviero
Publikováno v:
Marine Drugs, Vol 16, Iss 3, p 89 (2018)
Herein, we reported on the synthesis of cpIPP, which is a new structurally-reduced analogue of cyclic ADP-ribose (cADPR), a potent Ca2+-releasing secondary messenger that was firstly isolated from sea urchin eggs extracts. To obtain cpIPP the “nort
Externí odkaz:
https://doaj.org/article/41b39e743dec4da8bc77c0c7ad72d6a6
Publikováno v:
Journal of Chemistry, Vol 2015 (2015)
Heterochiral oligodeoxynucleotides based on the thrombin binding aptamer sequence, namely, 5′gg3′-3′TT5′-5′ggtgtgg3′-3′TT5′-5′gg3′ (H1), 5′gg3′-3′TT5′-5′gg3′-3′TGT5′-5′gg3′-3′TT5′-5′gg3′ (H2), and 5′g
Externí odkaz:
https://doaj.org/article/7ede7e25476f4101bac84499484bc5b9
Autor:
Bruno Pagano, Iolanda Fotticchia, Stefano De Tito, Carlo A. Mattia, Luciano Mayol, Ettore Novellino, Antonio Randazzo, Concetta Giancola
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Guanine-rich nucleic acid sequences can adopt G-quadruplex structures stabilized by layers of four Hoogsteen-paired guanine residues. Quadruplex-prone sequences are found in many regions of human genome and in the telomeres of all eukaryotic organism
Externí odkaz:
https://doaj.org/article/8c8ceca9e031469293242662a96b93b5
Autor:
Luigi D’Elia, Matteo Lorito, Federica Carraturo, Edvige Gambino, Sheridan L. Woo, Antonino Pollio, Marco Guida, Francesco Vinale, Lorenzo De Napoli, Luciano Mayol, Roberta Marra, Roberto Barone, Marina Paolucci, Maria Grazia Volpe
Publikováno v:
Marine Drugs
Marine Drugs, Vol 18, Iss 3, p 169 (2020)
Volume 18
Issue 3
Marine Drugs, Vol 18, Iss 3, p 169 (2020)
Volume 18
Issue 3
Algae have multiple similarities with fungi, with both belonging to the Thallophyte, a polyphyletic group of non-mobile organisms grouped together on the basis of similar characteristics, but not sharing a common ancestor. The main difference between
Autor:
Antonietta Pepe, Isabel M. Gomez Monterrey, Francesca Esposito, Luciano Mayol, Antonella Virgilio, Aldo Galeone, Enzo Tramontano, Veronica Esposito
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 5637, p 5637 (2020)
International Journal of Molecular Sciences
Volume 21
Issue 16
International Journal of Molecular Sciences
Volume 21
Issue 16
In this paper, we report studies concerning four variants of the G-quadruplex forming anti-HIV-integrase aptamer T30923, in which specific 2&prime
deoxyguanosines have been singly replaced by 8-methyl-2&prime
deoxyguanosine residues, with t
deoxyguanosines have been singly replaced by 8-methyl-2&prime
deoxyguanosine residues, with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01b9cfe09041296f25f4681e8db89687
http://hdl.handle.net/11588/848070
http://hdl.handle.net/11588/848070