Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Luciano G. Martellotto"'
Autor:
Shoukat Dedhar, Jason E. Cain, Luciano G. Martellotto, Badia Maria Barakat, Gregory E. Hannigan, Liang Yu, Elisabetta De Luca, Die Wang, Anthony J. Sadler, D. Neil Watkins, Camden Lo, Duc Vu
Publikováno v:
EMBO reports. 14:945-945
Here we report that ILK localizes in the mouse primary cilium, a sensory organelle required for signalling by the Hedgehog (Hh) pathway. Genetic or pharmacological inhibition of ILK blocks ciliary accumulation of the Hh pathway effector smoothened (S
Publikováno v:
Cancer Research. 70:995-995
The Hedgehog (Hh) signaling pathway is a highly conserved system for regulating metazoan development and cell fate. Integrin linked kinase (ILK) is required for proliferation of Hh-dependent neurons in the mammalian cerebellum, which also give rise t
Interaction of smoothened with integrin-linked kinase in primary cilia mediates Hedgehog signalling.
Autor:
Barakat, Badia, Yu, Liang, Lo, Camden, Vu, Duc, De Luca, Elisabetta, Cain, Jason E, Martellotto, Luciano G, Dedhar, Shoukat, Sadler, Anthony J, Wang, Die, Watkins, D Neil, Hannigan, Gregory E
Publikováno v:
EMBO Reports; Oct2013, Vol. 14 Issue 10, p945-945, 1p