Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Luciano, Conti"'
Autor:
Dilara Ayyildiz, Guendalina Bergonzoni, Alan Monziani, Takshashila Tripathi, Jessica Döring, Emanuela Kerschbamer, Francesca Di Leva, Elia Pennati, Luisa Donini, Marina Kovalenko, Jacopo Zasso, Luciano Conti, Vanessa C Wheeler, Christoph Dieterich, Silvano Piazza, Erik Dassi, Marta Biagioli
Publikováno v:
PLoS Genetics, Vol 19, Iss 10, p e1010988 (2023)
Alternative splicing (AS) appears to be altered in Huntington's disease (HD), but its significance for early, pre-symptomatic disease stages has not been inspected. Here, taking advantage of Htt CAG knock-in mouse in vitro and in vivo models, we demo
Externí odkaz:
https://doaj.org/article/87731a943eda4263b60cff414dc33cfe
Autor:
Alessandro Umbach, Giulia Maule, Eyemen Kheir, Alessandro Cutarelli, Marika Foglia, Luca Guarrera, Luca L. Fava, Luciano Conti, Enrico Garattini, Mineko Terao, Anna Cereseto
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-13 (2022)
Abstract Background Cornelia de Lange syndrome (CdLS) is a rare multisystem genetic disorder which is caused by genetic defects involving the Nipped-B-like protein (NIPBL) gene in the majority of clinical cases (60–70%). Currently, there are no spe
Externí odkaz:
https://doaj.org/article/a3317733e436485fa7844778aed951b2
Autor:
Francesco Antonica, Lucia Santomaso, Davide Pernici, Linda Petrucci, Giuseppe Aiello, Alessandro Cutarelli, Luciano Conti, Alessandro Romanel, Evelina Miele, Toma Tebaldi, Luca Tiberi
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Pediatric and adult high-grade gliomas are the most common primary malignant brain tumors, with poor prognosis due to recurrence and tumor infiltration after therapy. Quiescent cells have been implicated in tumor recurrence and treatment res
Externí odkaz:
https://doaj.org/article/43efb7b47c3b48e68e112be0007905f9
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
Externí odkaz:
https://doaj.org/article/81365e1816a54f4ba2151a2cb7060516
Autor:
Claudia Guerriero, Marianna Manfredelli, Carlo Matera, Angela Iuzzolino, Luciano Conti, Clelia Dallanoce, Marco De Amici, Daniela Trisciuoglio, Ada Maria Tata
Publikováno v:
Cancers, Vol 16, Iss 1, p 25 (2023)
Background: Although autophagy is a pro-survival process of tumor cells, it can stimulate cell death in particular conditions and when differently regulated by specific signals. We previously demonstrated that the selective stimulation of the M2 musc
Externí odkaz:
https://doaj.org/article/160599c51bcd4158a79d7fcd903572ef
Autor:
Marilyn M. Angulo Salavarria, Claudia Dell’Amico, Armando D’Agostino, Luciano Conti, Marco Onorati
Publikováno v:
Frontiers in Neuroanatomy, Vol 17 (2023)
The human brain is the most complex structure generated during development. Unveiling the ontogenesis and the intrinsic organization of specific neural networks may represent a key to understanding the physio-pathological aspects of different brain a
Externí odkaz:
https://doaj.org/article/cb8a78f4732f4143ae083372a86fd52d
Publikováno v:
Ensaio Pesquisa em Educação em Ciências, Vol 24 (2022)
RESUMO: A investigação desenvolvida objetivou: analisar os conteúdos abordados pelas disciplinas de astronomia em universidades públicas do país, ora separado por esfera federal ou estadual, ora comparativamente, no intuito de se compreender qua
Externí odkaz:
https://doaj.org/article/32d99c4851e2417a90320def3ae398c4
Autor:
Ingrid Battistella, Alessandro Cutarelli, Jacopo Zasso, Massimo Clerici, Carlo Sala, Matteo Marcatili, Luciano Conti
Publikováno v:
Journal of Personalized Medicine, Vol 13, Iss 3, p 538 (2023)
Astrocytes coordinate several homeostatic processes of the central nervous system and play essential roles for normal brain development and response to disease conditions. Protocols for the conversion of human induced pluripotent stem cells (hiPSCs)
Externí odkaz:
https://doaj.org/article/d85fd7b0e3f34dc5926fe3d8f9a989b9
Autor:
Valentina Gilmozzi, Giovanna Gentile, Diana A. Riekschnitz, Michael Von Troyer, Alexandros A. Lavdas, Emanuela Kerschbamer, Christian X. Weichenberger, Marcelo D. Rosato-Siri, Simona Casarosa, Luciano Conti, Peter P. Pramstaller, Andrew A. Hicks, Irene Pichler, Alessandra Zanon
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 9 (2021)
Human induced pluripotent stem cells (hiPSCs) represent an unlimited cell source for the generation of patient-specific dopaminergic (DA) neurons, overcoming the hurdle of restricted accessibility to disease-affected tissue for mechanistic studies on
Externí odkaz:
https://doaj.org/article/1b46ad349975430cac3e8b75a86ac04d
Autor:
Cecilia Cattelani, Ingrid Battistella, Francesca Di Leva, Giulia Fioravanti, Francesco Benedicenti, Franco Stanzial, Christine Schwienbacher, Francesca Fanelli, Peter P. Pramstaller, Andrew A. Hicks, Luciano Conti, Corrado Corti
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 21, p 13095 (2022)
Mutations in the SZT2 gene have been associated with developmental and epileptic encephalopathy-18, a rare severe autosomal recessive neurologic disorder, characterized by psychomotor impairment/intellectual disability, dysmorphic facial features and
Externí odkaz:
https://doaj.org/article/6e5907e8f28d430db07c7fd1665fdc3c