Zobrazeno 1 - 10 of 15 pro vyhledávání: '"Luciano, Amarelle"'
1
Akademický článek
Novel opportunities from bioimaging to understand the trafficking and maturation of intracellular pulmonary surfactant and its role in lung diseases
Autor: María José Garcia, Luciano Amarelle, Leonel Malacrida, Arturo Briva
Publikováno v: Frontiers in Immunology, Vol 14 (2023)
Pulmonary surfactant (PS), a complex mixture of lipids and proteins, is essential for maintaining proper lung function. It reduces surface tension in the alveoli, preventing collapse during expiration and facilitating re-expansion during inspiration.
Externí odkaz: https://doaj.org/article/6641f1c1c5984274bc6ca760fb04ea32
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2
Akademický článek
Hyperoxia and Lungs: What We Have Learned From Animal Models
Autor: Luciano Amarelle, Lucía Quintela, Javier Hurtado, Leonel Malacrida
Publikováno v: Frontiers in Medicine, Vol 8 (2021)
Although oxygen (O2) is essential for aerobic life, it can also be an important source of cellular damage. Supra-physiological levels of O2 determine toxicity due to exacerbated reactive oxygen species (ROS) production, impairing the homeostatic bala
Externí odkaz: https://doaj.org/article/db90a66f1d664812963ff981a575c13d
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3
Cardiac glycosides decrease influenza virus replication by inhibiting cell protein translational machinery
Autor: Diego Celli, Susanne Herold, Hector R. Cajigas, Emilia Lecuona, Jacob I. Sznajder, Lynn C. Welch, Christin Peteranderl, Jeremy Katzen, Masahiko Shigemura, Luciano Amarelle
Publikováno v: Am J Physiol Lung Cell Mol Physiol
Cardiac glycosides (CGs) are used primarily for cardiac failure and have been reported to have other effects, including inhibition of viral replication. Here we set out to study mechanisms by which CGs as inhibitors of the Na-K-ATPase decrease influe
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::898d6616978cf0a7ac18aaec021321d7
https://doi.org/10.1152/ajplung.00173.2018
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4
Influenza A Virus Infection Induces Muscle Wasting via IL-6 Regulation of the E3 Ubiquitin Ligase Atrogin-1
Autor: Masahiko Shigemura, Emilia Lecuona, Monica Chi, G. R. Scott Budinger, Constance E. Runyan, Luisa Morales-Nebreda, Laura A. Dada, Atsuko Shigemura, Gökhan M. Mutlu, Kathryn A. Radigan, Harris Perlman, Martín Angulo, Alexander V. Misharin, Lynn C. Welch, Ermelinda Ceco, Trevor T. Nicholson, Luciano Amarelle, Jacob I. Sznajder
Publikováno v: The Journal of Immunology. 202:484-493
Muscle dysfunction is common in patients with adult respiratory distress syndrome and is associated with morbidity that can persist for years after discharge. In a mouse model of severe influenza A pneumonia, we found the proinflammatory cytokine IL-
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5988730bcf0735058342e5cde7b0e9de
https://doi.org/10.4049/jimmunol.1701433
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8
Tratamiento antigripal: fármacos actualmente utilizados y nuevos agentes en desarrollo
Autor: Emilia Lecuona, Luciano Amarelle, Jacob I. Sznajder
Publikováno v: Archivos de Bronconeumología
Resumen La gripe es una enfermedad contagiosa altamente prevalente y con significativa morbimortalidad. El tratamiento disponible con farmacos antivirales, de ser administrado de forma precoz, puede reducir el riesgo de complicaciones severas; sin em
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d870fe6f4712df904a299c836061883
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Plný text Recenzováno Digitální knihovna AV ČR
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