Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Luciana de Andrade Agostinho"'
Autor:
Tiago César Gouvêa Moreira, Pricila da Silva Spínola, Micheline Campos Rezende, Carla Simone Moreira de Freitas, Fábio Borges Mury, Cibele Rodrigues Bonvicino, Luciana de Andrade Agostinho
Publikováno v:
Biomédica: revista del Instituto Nacional de Salud, Vol 41, Iss 4, Pp 773-786 (2021)
Introduction: Next Generation Sequencing (NGS) is cost-effective and a faster method to study genes, but its protocol is challenging. Objective: To analyze different adjustments to the protocol for screening the BRCA genes using Ion Torrent PGM seque
Externí odkaz:
https://doaj.org/article/8fdcb9a86d294d89bce01e47e60ba678
Publikováno v:
Brazilian Archives of Biology and Technology, Vol 64 (2021)
Abstract High sensitivity of qPCR assay can be compromised by the presence of PCR inhibitors in samples analyzed. The aim of this study was to analyze the RT-qPCR assay efficiency considering the RNA quality/quantity and the presence of PCR inhibitor
Externí odkaz:
https://doaj.org/article/0a3ce2200fc24f8a84c1cb485e210787
Autor:
Guilherme Wilson Souza Silveira, Dionatan Costa Rodrigues, Clarissana Araújo Botaro, Luciana de Andrade Agostinho
Publikováno v:
Arquivos de Ciências da Saúde, Vol 27, Iss 1 (2020)
Introdução: A doença de Huntington (DH) é uma desordem neurodegenerativa autossômica dominante e rara, com comprometimento motor, cognitivo e comportamental. O início dos sintomas precoces, com menos de 20 anos, caracteriza a forma infanto-juve
Externí odkaz:
https://doaj.org/article/b6f9abaff4a94938ad55cf656983a232
Autor:
Thays A. Apolinário, Iane dos Santos daSilva, Luciana de Andrade Agostinho, Carmen L. A. Paiva
Publikováno v:
Molecular Genetics & Genomic Medicine, Vol 8, Iss 4, Pp n/a-n/a (2020)
Abstract Background Huntington disease (HD) (MIM: 143100) is a severe autosomal dominant neurodegenerative disease caused by the expansion of CAG trinucleotides (>35) in the HTT. Objective To investigate the frequency of intermediate CAG alleles (IAs
Externí odkaz:
https://doaj.org/article/23a22e9b510f45bfb8d80a4b84d72d03
Autor:
Tiago César Gouvêa Moreira, Caio Agostini Calheiros Grosso Grosso, Luciana de Andrade Agostinho
Publikováno v:
Journal of Biotechnology and Biodiversity. 9:149-162
Este estudo teve como objetivo analisar variantes encontradas nos genes BRCA1 e BRCA2 com intuito de comparar as diferentes predições in silico de ferramentas distintas, além de investigar variantes candidatas à desequilíbrio de ligação (LD).
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c4b826376cea997373ab87c578e58b5d
https://doi.org/10.20873/jbb.uft.cemaf.v9n2.grosso
https://doi.org/10.20873/jbb.uft.cemaf.v9n2.grosso
Autor:
Carmen Lucia Antão Paiva, Mayra Braga Lemos, Thays Andrade Apolinário, Luciana de Andrade Agostinho, Dionatan Costa Rodrigues
Publikováno v:
Clinical Medicine & Research. 18:145-152
Background Huntington's disease (HD)(MIM:143100) is an severe autosomal dominant neurodegenerative disease caused by the dynamic expansion of CAG trinucleotides (> 35) in the HTT gene [Genomic Coordinates- (GRCh38):4:3,074,680-3,243,959]. Objectives
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f5a0a4b114a68367d846748da6a24bc9
https://doi.org/10.3121/cmr.2020.1523
https://doi.org/10.3121/cmr.2020.1523
Autor:
Luciana de Andrade Agostinho, Carmen Lucia Antão Paiva, Iane dos Santos da Silva, Thays Andrade Apolinário
Huntington's disease (HD) is a genetic neurodegenerative progressive and fatal disease characterized by motor disorder, cognitive impairment and behavioral problems, caused by expanded repeats of CAG trinucleotides in the HTT gene. The aim of this st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::468759292273313b49712458f5551a4b
https://doi.org/10.21203/rs.3.rs-680274/v1
https://doi.org/10.21203/rs.3.rs-680274/v1
Autor:
Iane dos Santos da Silva, Thays Andrade Apolinário, Luciana de Andrade Agostinho, Carmen Lucia Antão Paiva
Publikováno v:
Journal of molecular neuroscience : MN. 72(5)
Huntington's disease (HD) is a genetic neurodegenerative progressive and fatal disease characterized by motor disorder, cognitive impairment, and behavioral problems, caused by expanded repeats of CAG trinucleotides in the HTT gene. The aim of this s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fc0f6a3044faeb3be40ffec9f4fe02b
https://pubmed.ncbi.nlm.nih.gov/35275350
https://pubmed.ncbi.nlm.nih.gov/35275350
Autor:
Amanda Ribeiro de Oliveira, Maurício Drummond Alves, Alice Muglia Tomaz da Silva Amancio, Luciana de Andrade Agostinho, Tiago César Gouvêa Moreira
Publikováno v:
Revista Brasileira de Análises Clínicas. 53
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7df9e0f0971e0f634a848345f4ba0566
https://doi.org/10.21877/2448-3877.202102032
https://doi.org/10.21877/2448-3877.202102032
Autor:
Lais Gonçalves Parvan, Polyana Aparecida Almeida Pedrosa, Thaynara Barbosa Freitas, Thaís Gonçalves Leite, Luciana de Andrade Agostinho, Juliana Sena Calixto
Publikováno v:
Revista Pan-Amazônica de Saúde. 11
RESUMO OBJETIVO: Analisar o potencial genotoxico de um herbicida com flumioxazina pelo bioensaio Allium cepa. MATERIAIS E METODOS: O herbicida foi testado em duas concentracoes: 0,5 g/L (concentracao indicada para o uso) e 1,0 g/L (dobro da concentra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a74e571b4ce43140ab99f14ad67b8dfc
https://doi.org/10.5123/s2176-6223202000544
https://doi.org/10.5123/s2176-6223202000544