Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Luciana Stanica"'
Autor:
Luciana Stanica, Mihaela Gheorghiu, Miruna Stan, Cristina Polonschii, Sorin David, Dumitru Bratu, Anca Dinischiotu, Claudiu T. Supuran, Eugen Gheorghiu
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1079-1090 (2017)
Carbonic anhydrase IX (CA IX) is an important orchestrator of hypoxic tumour environment, associated with tumour progression, high incidence of metastasis and poor response to therapy. Due to its tumour specificity and involvement in associated patho
Externí odkaz:
https://doaj.org/article/cc5ea295094845928df00a6d012b252a
Publikováno v:
ChemElectroChem. 6:1800-1807
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::be12ccf939cf15c0ac1363b18a14d1ee
https://doi.org/10.1002/celc.201801558
https://doi.org/10.1002/celc.201801558
Autor:
Mihaela Gheorghiu, Cristina Polonschii, Andrei E. Ruckenstein, Sorin David, Luciana Stanica, Tudor C. Badea, Octavian Popescu, Eugen Gheorghiu
Publikováno v:
Anal Chem
Cell-based sensing platforms provide functional information on cellular effects of bioactive or toxic compounds in a sample. Current challenges concern the rather extended length of the assays as well as their limited reproducibility and sensitivity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::60da63c54234c89b2275087d33b3a0ff
https://europepmc.org/articles/PMC7641241/
https://europepmc.org/articles/PMC7641241/
Autor:
Miruna Silvia Stan, Mihaela Gheorghiu, Loredana Antonescu, Cristina Polonschii, Eugen Gheorghiu, Luciana Stanica, Mihnea Rosu-Hamzescu
Publikováno v:
Journal of Sensors, Vol 2017 (2017)
Tumor hypoxia provides a dynamic environment for the cancer cells to thrive and metastasize. Evaluation of cell growth, cell-cell, and cell surface interactions in hypoxic conditions is therefore highly needed in the establishment of treatment option
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71cc1dbe015c63f4b0dc1c06aabd0066
https://doi.org/10.1155/2017/9290478
https://doi.org/10.1155/2017/9290478
Autor:
Luciana Stanica, Eugen Gheorghiu, Tudor C. Badea, Dumitru Bratu, Mihaela Gheorghiu, Octavian Popescu, Miruna G. Ghinia Tegla, Cristina Polonschii
Publikováno v:
Biosens Bioelectron
We demonstrate a new biosensing concept with impact on the development of rapid, point of need cell based sensing with boosted sensitivity and wide relevance for bioanalysis. It involves optogenetic stimulation of cells stably transfected to express
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3a14871c282609e4ebed2f9268f69ce7
https://doi.org/10.1016/j.bios.2019.112003
https://doi.org/10.1016/j.bios.2019.112003
Autor:
Andra Cristocea, Valentina Marascu, Laura Gaman, Alina Vasilescu, Anca Bonciu, Mihaela Gheorghiu, Simion Astilean, Luciana Stanica, Valentina Dinca, Diana Zaharie-Butucel, Simona Brajnicov
Publikováno v:
Colloids and surfaces. B, Biointerfaces. 162
Whole cell optical biosensors, made by immobilizing whole algal, bacterial or mammalian cells on various supports have found applications in several fields, from ecology and ecotoxicity testing to biopharmaceutical production or medical diagnostics.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ae77d0b84737ec3f25807d09ec42f51
https://pubmed.ncbi.nlm.nih.gov/29190474
https://pubmed.ncbi.nlm.nih.gov/29190474
Autor:
Dumitru Bratu, Luciana Stanica, Eugen Gheorghiu, Cristina Polonschii, Sorin David, Miruna Silvia Stan, Anca Dinischiotu, Mihaela Gheorghiu, Claudiu T. Supuran
Publikováno v:
Journal of Enzyme Inhibition and Medicinal Chemistry, Vol 32, Iss 1, Pp 1079-1090 (2017)
Journal of Enzyme Inhibition and Medicinal Chemistry
Journal of Enzyme Inhibition and Medicinal Chemistry
Carbonic anhydrase IX (CA IX) is an important orchestrator of hypoxic tumour environment, associated with tumour progression, high incidence of metastasis and poor response to therapy. Due to its tumour specificity and involvement in associated patho
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4faea433460d90dc3fb6d0146f56629a
Autor:
Hubert H. Girault, Szilveszter Gáspár, Andreas Lesch, Mihaela Gheorghiu, Alexandra Bondarenko, Eugen Gheorghiu, Luciana Stanica, Fernando Cortés-Salazar, Dmitry Momotenko
Publikováno v:
Analytical chemistry. 87(8)
To understand biological processes at the cellular level, a general approach is to alter the cells' environment and to study their chemical responses. Herein, we present the implementation of an electrochemical push-pull probe, which combines a micro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5c55b9bc3d73505973e07691340c8f2
https://pubmed.ncbi.nlm.nih.gov/25833001
https://pubmed.ncbi.nlm.nih.gov/25833001
Autor:
Dana Cucu, Roxana Ulăreanu, Violeta Ristoiu, Gabriela Chiriţoiu, Alexandru Deftu, Florentina Cojocaru, Dan Mihailescu, Luciana Stanica
Publikováno v:
Tumor Biology, Vol 39 (2017)
Transient receptor potential melastatin 8 (TRPM8), a membrane ion channel, is activated by thermal and chemical stimuli. In pancreatic ductal adenocarcinoma, TRPM8 is required for cell migration, proliferation, and senescence and is associated with t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::781d27b5b63e5c23f542521953b250b6
https://doi.org/10.1177/1010428317720940
https://doi.org/10.1177/1010428317720940
Autor:
Roxana Ulăreanu, Gabriela Chiriţoiu, Florentina Cojocaru, Alexandru Deftu, Violeta Ristoiu, Luciana Stănică, Dan F Mihăilescu, Dana Cucu
Publikováno v:
Tumor Biology, Vol 39 (2017)
Transient receptor potential melastatin 8 (TRPM8), a membrane ion channel, is activated by thermal and chemical stimuli. In pancreatic ductal adenocarcinoma, TRPM8 is required for cell migration, proliferation, and senescence and is associated with t
Externí odkaz:
https://doaj.org/article/317c47463fc94e82ac26528d5f9ecc28