Zobrazeno 1 - 10
of 366
pro vyhledávání: '"Luciana Scotti"'
Autor:
Thalisson A. de Souza, Luiz H. A. Pereira, Alan F. Alves, Douglas Dourado, Jociano da S. Lins, Marcus T. Scotti, Luciana Scotti, Lucas S. Abreu, Josean F. Tavares, Marcelo S. Silva
Publikováno v:
Pharmaceuticals, Vol 17, Iss 10, p 1399 (2024)
The Euphorbiaceae family is a rich source of bioactive terpenoids. Among its genera, Jatropha is a conspicuous producer of diterpenes and includes approximately 175 species, many of which have medicinal uses. To date, 140 diterpenes from Jatropha (JT
Externí odkaz:
https://doaj.org/article/993915aeac3d4182bfb6dffb724df5bf
Publikováno v:
Química Nova, Vol 47, Iss 7 (2024)
Over the years the study of the quantitative structure-activity relationship (QSAR) has transformed from a simple regression analysis to the implementation of machine learning (ML) with multiple statistics. Today ML-based QSAR models are quite import
Externí odkaz:
https://doaj.org/article/79aa2cd09cc84a89839a0fd971cacbd3
Autor:
Saurabh G. Londhe, Vinayak Walhekar, Mangala Shenoy, Suvarna G. Kini, Marcus T. Scotti, Luciana Scotti, Dileep Kumar
Publikováno v:
Pharmaceutics, Vol 16, Iss 8, p 991 (2024)
Background: Alzheimer’s disease is a serious and widespread neurodegenerative illness in the modern healthcare scenario. GSK-3β and BuChE are prominent enzymatic targets associated with Alzheimer’s disease. Co-targeting GSK3β and BChE in Alzhei
Externí odkaz:
https://doaj.org/article/4b9c74abad674278a1715342792e87a7
Autor:
Natália Ferreira de Sousa, Gabrielly Diniz Duarte, Carolina Borsoi Moraes, Cecília Gomes Barbosa, Holli-Joi Martin, Nail N. Muratov, Yuri Mangueira do Nascimento, Luciana Scotti, Lúcio Holanda Gondim de Freitas-Júnior, José Maria Barbosa Filho, Marcus Tullius Scotti
Publikováno v:
Pharmaceutics, Vol 16, Iss 7, p 912 (2024)
In 2019, the emergence of the seventh known coronavirus to cause severe illness in humans triggered a global effort towards the development of new drugs and vaccines for the SARS-CoV-2 virus. These efforts are still ongoing in 2024, including the pre
Externí odkaz:
https://doaj.org/article/291d71d6f69f4c8c9fca576dbc687759
Autor:
Gleycyelly Rodrigues Araújo, Palloma Christine Queiroga Gomes da Costa, Paula Lima Nogueira, Danielle da Nóbrega Alves, Alana Rodrigues Ferreira, Pablo R. da Silva, Jéssica Cabral de Andrade, Natália F. de Sousa, Paulo Bruno Araujo Loureiro, Marianna Vieira Sobral, Damião P. Sousa, Marcus Tullius Scotti, Ricardo Dias de Castro, Luciana Scotti
Publikováno v:
BioTech, Vol 13, Iss 2, p 16 (2024)
Candida species are frequently implicated in the development of both superficial and invasive fungal infections, which can impact vital organs. In the quest for novel strategies to combat fungal infections, there has been growing interest in explorin
Externí odkaz:
https://doaj.org/article/1757b74146974c43a49c6385aac064b8
Autor:
Maria Camila Muñoz-Vega, Sofía López-Hernández, Adrián Sierra-Chavarro, Marcus Tullius Scotti, Luciana Scotti, Ericsson Coy-Barrera, Chonny Herrera-Acevedo
Publikováno v:
Molecules, Vol 29, Iss 1, p 179 (2023)
The critical enzyme dihydrofolate reductase-thymidylate synthase in Leishmania major (LmDHFR-TS) serves a dual-purpose role and is essential for DNA synthesis, a cornerstone of the parasite’s reproductive processes. Consequently, the development of
Externí odkaz:
https://doaj.org/article/999e2b63d4f84e6b94ee2cdd1ad25806
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Externí odkaz:
https://doaj.org/article/5a285428777b4adf875bf2543d6c1794
Autor:
Rafael Carlos Ferreira, Sâmia Sousa Duarte, Valgrícia Matias de Sousa, Ramon Ramos Marques de Souza, Karinne Kelly Gadelha Marques, Renata Albuquerque de Abrantes, Yuri Mangueira do Nascimento, Natália Ferreira de Sousa, Marcus Tullius Scotti, Luciana Scotti, Josean Fechine Tavares, Juan Carlos Ramos Gonçalves, Marcelo Sobral da Silva, Marianna Vieira Sobral
Publikováno v:
Pharmaceuticals, Vol 16, Iss 11, p 1553 (2023)
The characterization and cytotoxicity of the essential oil from Conyza bonariensis (L.) aerial parts (CBEO) were previously conducted. The major compound was (Z)-2-lachnophyllum ester (EZ), and CBEO exhibited significant ROS-dependent cytotoxicity in
Externí odkaz:
https://doaj.org/article/17fc57ea2e7f4e27bfa0afd8002f4d97
Methyleugenol Has an Antidepressant Effect in a Neuroendocrine Model: In Silico and In Vivo Evidence
Autor:
Mayara Cecile Nascimento Oliveira, Ikla Lima Cavalcante, Alana Natalícia de Araújo, Aline Matilde Ferreira dos Santos, Renata Priscila Barros de Menezes, Chonny Herrera-Acevedo, Natália Ferreira de Sousa, Jailane de Souza Aquino, José Maria Barbosa-Filho, Ricardo Dias de Castro, Reinaldo Nóbrega Almeida, Luciana Scotti, Marcus Tullius Scotti, Mirian Graciela Da Silva Stiebbe Salvadori
Publikováno v:
Pharmaceuticals, Vol 16, Iss 10, p 1408 (2023)
Major depressive disorder is a severe mood disorder characterized by different emotions and feelings. This study investigated the antidepressant activity of the phenylpropanoid methyleugenol (ME) in adult female mice exposed to a stress model induced
Externí odkaz:
https://doaj.org/article/ba1b02714ade488ab55c6e8bc7971b66
Autor:
Renata Priscila Barros de Menezes, Jéssika de Oliveira Viana, Eugene Muratov, Luciana Scotti, Marcus Tullius Scotti
Publikováno v:
Current Issues in Molecular Biology, Vol 44, Iss 1, Pp 383-408 (2022)
Schistosomiasis is a chronic parasitic disease caused by trematodes of the genus Schistosoma; it is commonly caused by Schistosoma mansoni, which is transmitted by Bioamphalaria snails. Studies show that more than 200 million people are infected and
Externí odkaz:
https://doaj.org/article/1e697a89e1cb4e71ae7be602ab79e1de