Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Luciana P. Rangel"'
Autor:
Mariana M. Paz, Giulia D. S. Ferretti, Mafalda M. C. Martins-Dinis, Beatriz I. S. Ferreira, Amanda Faier-Pereira, Thibaut Barnoud, Otacilio C. Moreira, Jerson L. Silva, Yraima Cordeiro, Luciana P. Rangel
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer-related deaths worldwide. Although many therapeutic options are available, several factors, including the presence of p53 mutations, impact tumor development and therapeutic resistan
Externí odkaz:
https://doaj.org/article/a63a21b730f141c89ca914e08c92a1d4
Autor:
Jerson L. Silva, Carolina G. S. Lima, Luciana P. Rangel, Giulia D. S. Ferretti, Fernanda P. Pauli, Ruan C. B. Ribeiro, Thais de B. da Silva, Fernando C. da Silva, Vitor F. Ferreira
Publikováno v:
Biomolecules, Vol 10, Iss 4, p 635 (2020)
The tumor suppressor protein p53 is often called “the genome guardian” and controls the cell cycle and the integrity of DNA, as well as other important cellular functions. Its main function is to trigger the process of apoptosis in tumor cells, a
Externí odkaz:
https://doaj.org/article/da38a9be29814f4988a169ca7879e10a
Publikováno v:
Frontiers in Oncology, Vol 5 (2015)
The current understanding of the molecular mechanisms that lead to cancer is not sufficient to explain the loss or gain of function in proteins related to tumorigenic processes. Among them, more than 100 oncogenes, 20-30 tumor suppressor genes and hu
Externí odkaz:
https://doaj.org/article/a28c52fa30d244029caf123348444d40
Publikováno v:
Schème: Revista Eletrônica de Psicologia e Epistemologia Genéticas, Vol 14, Iss 1 (2022)
Externí odkaz:
https://doaj.org/article/9ae2fcecd9184ca39c1189ab6e058bc3
Autor:
Amanda Rodrigues Pinto Costa, Marcelly Muxfeldt, Fernanda da Costa Santos Boechat, Maria Cecília Bastos Vieira de Souza, Jerson Lima Silva, Marcela Cristina de Moraes, Luciana Pereira Rangel, Tuane Cristine Ramos Gonçalves Vieira, Pedro Netto Batalha
Publikováno v:
Molecules, Vol 27, Iss 22, p 7935 (2022)
Prion Diseases or Transmissible Spongiform Encephalopathies are neurodegenerative conditions associated with a long incubation period and progressive clinical evolution, leading to death. Their pathogenesis is characterized by conformational changes
Externí odkaz:
https://doaj.org/article/a9ec09557c334c33bc36bc3e85a5b531
Autor:
Amanda Sousa Roveri, Luara Novaes Coutinho, Luciana Thais Rangel Souza, Lorena Gonçalves Cardoso, João Pedro Cotrim Maia, Anne Maria Guimarães Lessa
Publikováno v:
Revista Uningá, Vol 58 (2021)
A deficiência transversal maxilar é caracterizada como uma má oclusão que acomete pacientes de todas as faixas etárias. Para o seu correto tratamento é indicado a expansão rápida maxilar (ERM). Entretanto, há casos nos quais a terapia com ut
Externí odkaz:
https://doaj.org/article/ee5051d4658a46ce9c1e576b10d4376f
Akademický článek
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Publikováno v:
Toxins, Vol 12, Iss 7, p 465 (2020)
Phytoplankton anti-grazer traits control zooplankton grazing and are associated with harmful blooms. Yet, how morphological versus chemical phytoplankton defenses regulate zooplankton grazing is poorly understood. We compared zooplankton grazing and
Externí odkaz:
https://doaj.org/article/d369a31f3e8e441c961c8fc01edcea88
Publikováno v:
International journal of molecular sciences. 23(19)
p53 is a tumor suppressor protein that is mutated in more than 50% of cancer cases. When mutated, it frequently results in p53 oncogenic gain of function (GOF), resulting in a greater tendency to aggregate in the phase separation and phase transition
Autor:
Petar Stefanov Kovachev, Natália Ferreira, Mariana Pierre de Barros Gomes, Suparna Sanyal, Luciana P. Rangel, Leticia P. Felix Valadão, Lucas M. Ascari, Yraima Cordeiro, Jerson L. Silva
Publikováno v:
Scientific Reports, Vol 9, Iss 1, Pp 1-12 (2019)
Scientific Reports
Scientific Reports
Recent studies have proposed that nucleic acids act as potential cofactors for protein aggregation and prionogenesis. By means of sedimentation, transmission electron microscopy, circular dichroism, static and dynamic light scattering, we have studie