Decrease in Dengue virus-2 infection and reduction of cytokine/chemokine production by Uncaria guianensis in human hepatocyte cell line Huh-7

Autor: Cíntia da Silva Mello, Ligia Maria Marino Valente, Thiago Wolff, Raimundo Sousa Lima-Junior, Luciana Gomes Fialho, Cintia Ferreira Marinho, Elzinandes Leal Azeredo, Luzia Maria Oliveira-Pinto, Rita de Cássia Alves Pereira, Antonio Carlos Siani, Claire Fernandes Kubelka

Publikováno v: Memorias do Instituto Oswaldo Cruz, Vol 112, Iss 6, Pp 458-468

ABSTRACT BACKGROUND Dengue fever may present hemorrhages and cavitary effusions as result of exacerbated immune responses. We investigated hydro-alcoholic extracts from leaves (UGL) and bark (UGB) of the medicinal species Uncaria guinanensis with res

Externí odkaz: https://doaj.org/article/37098981471142648b2ba7c78016501a

Association of rs1285933 single nucleotide polymorphism in CLEC5A gene with dengue severity and its functional effects

Autor: Paulo Neves Baptista, Carla Maria Mola de Vasconcelos, Rivaldo Venâncio da Cunha, Luciana Gomes Fialho, Antonio G. Pacheco, Caroline Xavier-Carvalho, Luiz José de Souza, Patrícia Muniz Mendes Freire de Moura, Rodrigo Feliciano do Carmo, Naishe Matos Freire, Marli Tenório Cordeiro, Thiago Gomes de Toledo-Pinto, Luydson Richardson Silva Vasconcelos, Renata Duarte da Silva Cezar, Victor Edgar Fiestas Solorzano, Elzinandes Leal de Azeredo, Milton Ozório Moraes, Claire Fernandes Kubelka

Publikováno v: Human Immunology. 78:649-656

Outbreaks of the Zika, dengue, and chikungunya viruses, especially in the Americas, pose a global threat due to their rapid spread and difficulty controlling the vector. Extreme phenotypes are often observed, from asymptomatic to severe clinical mani

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d71b35ea3825964317e3edde1387e12b
https://doi.org/10.1016/j.humimm.2017.07.013

Antiviral and Immunomodulatory Effects of Norantea brasiliensis Choisy on Dengue Virus-2

Autor: Claire Fernandes Kubelka, Elzinandes Leal de Azeredo, Sônia Regina Nogueira Ignácio Reis, Maria Auxiliadora C. Kaplan, Maria Raquel Figueiredo, Vagner Pereira da Silva, Luciana Gomes Fialho

Publikováno v: Intervirology. 59:217-227

Background/Aims: Severe dengue fever is a result of exacerbated immune responses and no specific treatments are available. We evaluated the antiviral and immunomodulatory effects of Norantea brasiliensis Choisy. Methods: Human adherent monocytes infe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::170928b7ba8a8adab409ac9a054e4134
https://doi.org/10.1159/000455855

Erratum in ' Cissampelos sympodialis has anti-viral effect inhibiting dengue non-structural viral protein-1 and pro-inflammatory mediators' [Rev. Bras. Farmacogn. 26 (2016) 502–506]

Autor: Ana Luisa de Araujo Lima, Luciana Gomes Fialho, Cintia Ferreira Marinho, José Maria Barbosa Filho, Cíntia da Silva Mello, Fagner Carvalho Leite, Marcia Regina Piuvezam, Claire Fernandes Kubelka

Publikováno v: Revista Brasileira de Farmacognosia. 27(2)

In the article, “Cissampelos sympodialis has anti-viral effect inhibiting dengue non-structural viral protein-1 and pro-inflammatory mediators” [Rev. Bras. Farmacogn. 26 (2016) 502–506], the third author name “Luciana Gomez Fialho” has been

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1de24e39b0d01f006f987c5b98cd2bbc

Cissampelos sympodialis has anti-viral effect inhibiting dengue non-structural viral protein-1 and pro-inflammatory mediators

Autor: Ana Luisa de Araujo Lima, Claire Fernandes Kubelka, Marcia Regina Piuvezam, Fagner Carvalho Leite, Cintia Ferreira Marinho, Luciana Gomes Fialho, Cíntia da Silva Mello, José Maria Barbosa Filho

Publikováno v: Revista Brasileira de Farmacognosia, Volume: 26, Issue: 4, Pages: 502-506, Published: AUG 2016
Revista Brasileira de Farmacognosia v.26 n.4 2016
Revista Brasileira de Farmacognosia
Sociedade Brasileira de Farmacognosia (SBFgnosia)
instacron:SBFGNOSIA
Revista Brasileira de Farmacognosia, Vol 26, Iss 4, Pp 502-506
Revista Brasileira de Farmacognosia, Vol 26, Iss 4, Pp 502-506 (2016)

Dengue is the most important viral infection transmitted among humans by arthropod-borne. There are currently no vaccines or specific therapeutical treatment. Therefore, immunomodulatory compounds from plants have been widely examined for their antiv

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffea876dea4f744c0b00ceaa9cdc55d3
http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2016000400502&lng=en&tlng=en