Zobrazeno 1 - 10
of 120
pro vyhledávání: '"Luciana Chessa"'
Autor:
Sara Biagiotti, Ambra Barone, Mattia Paolo Aliano, Giulia Federici, Marco Malatesta, Caterina Caputi, Silvia Soddu, Vincenzo Leuzzi, Luciana Chessa, Mauro Magnani
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Most of the ATM variants associated with Ataxia Telangiectasia are still classified as variants with uncertain significance. Ataxia Telangiectasia is a multisystemic disorder characterized by “typical” and “atypical” phenotypes, with early-on
Externí odkaz:
https://doaj.org/article/b15e92c56b87431ca9e113d9d536b17a
Autor:
Michele Menotta, Sara Biagiotti, Chiara Spapperi, Sara Orazi, Luigia Rossi, Luciana Chessa, Vincenzo Leuzzi, Daniela D’Agnano, Annarosa Soresina, Roberto Micheli, Mauro Magnani
Publikováno v:
Orphanet Journal of Rare Diseases, Vol 12, Iss 1, Pp 1-7 (2017)
Abstract Background Ataxia Telangiectasia (AT) is a rare incurable genetic disease, caused by biallelic mutations in the Ataxia Telangiectasia-Mutated (ATM) gene. Treatment with glucocorticoid analogues has been shown to improve the neurological symp
Externí odkaz:
https://doaj.org/article/e8db8bd3c8c94f99bffffefa4e97cd51
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216668 (2019)
Oxidative stress has been shown to play a crucial role in the pathophysiology of the neurodegenerative disease Ataxia Telangiectasia. We have recently demonstrated that Dexamethasone treatment is able to counteract the oxidative state by promoting nu
Externí odkaz:
https://doaj.org/article/fa0b08b0369d4b678fc9620590b45b53
Autor:
Michele Menotta, Sara Orazi, Anna Maria Gioacchini, Chiara Spapperi, Anastasia Ricci, Luciana Chessa, Mauro Magnani
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195388 (2018)
Ataxia telangiectasia (A-T) is an incurable and rare hereditary syndrome. In recent times, treatment with glucocorticoid analogues has been shown to improve the neurological symptoms that characterize this condition, but the molecular mechanism of ac
Externí odkaz:
https://doaj.org/article/7e380e16779645fe85a98781283005ad
Autor:
Jlenia Elia, Rossella Mazzilli, Michele Delfino, Maria Piane, Cristina Bozzao, Vincenzo Spinosa, Luciana Chessa, Fernando Mazzilli
Publikováno v:
Archivio Italiano di Urologia e Andrologia, Vol 86, Iss 3, Pp 171-174 (2014)
Objective. The aim of this study was to evaluate the prevalence of most common mutations and intron 8 5T (IVS8-5T) polymorphism of CFTR gene in Italian: a) azoospermic males; b) non azoospermic subjects, male partners of infertile couples enrolled in
Externí odkaz:
https://doaj.org/article/ec8d82581b2040a685933287f3ce9674
Autor:
Daria C Loconte, Valentina Grossi, Cristina Bozzao, Giovanna Forte, Rosanna Bagnulo, Alessandro Stella, Patrizia Lastella, Mario Cutrone, Francesco Benedicenti, Francesco C Susca, Margherita Patruno, Dora Varvara, Aldo Germani, Luciana Chessa, Nicola Laforgia, Romano Tenconi, Cristiano Simone, Nicoletta Resta
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0123092 (2015)
PIK3CA-related overgrowth spectrum (PROS) include a group of disorders that affect only the terminal portion of a limb, such as type I macrodactyly, and conditions like fibroadipose overgrowth (FAO), megalencephaly-capillary malformation (MCAP) syndr
Externí odkaz:
https://doaj.org/article/5e9db8d3b6bc440091a6a1de16ab9fcb
Autor:
Jean-Luc Perfettini, Roberta Nardacci, Mehdi Bourouba, Frédéric Subra, Laurent Gros, Claire Séror, Gwenola Manic, Filippo Rosselli, Alessandra Amendola, Peggy Masdehors, Luciana Chessa, Giuseppe Novelli, David M Ojcius, Jan Konrad Siwicki, Magdalena Chechlinska, Christian Auclair, José R Regueiro, Hugues de Thé, Marie-Lise Gougeon, Mauro Piacentini, Guido Kroemer
Publikováno v:
PLoS ONE, Vol 3, Iss 6, p e2458 (2008)
DNA damage can activate the oncosuppressor protein ataxia telangiectasia mutated (ATM), which phosphorylates the histone H2AX within characteristic DNA damage foci. Here, we show that ATM undergoes an activating phosphorylation in syncytia elicited b
Externí odkaz:
https://doaj.org/article/15997d8a8c2b4aaeb617c9750ec6c13c
Autor:
Emilia Cirillo, Agata Polizzi, Annarosa Soresina, Rosaria Prencipe, Giuliana Giardino, Caterina Cancrini, Andrea Finocchi, Beatrice Rivalta, Rosa M. Dellepiane, Lucia A. Baselli, Davide Montin, Antonino Trizzino, Rita Consolini, Chiara Azzari, Silvia Ricci, Lorenzo Lodi, Isabella Quinti, Cinzia Milito, Lucia Leonardi, Marzia Duse, Maria Carrabba, Giovanna Fabio, Patrizia Bertolini, Paola Coccia, Irene D’Alba, Andrea Pession, Francesca Conti, Marco Zecca, Claudio Lunardi, Manuela Lo Bianco, Santiago Presti, Laura Sciuto, Roberto Micheli, Dario Bruzzese, Vassilios Lougaris, Raffaele Badolato, Alessandro Plebani, Luciana Chessa, Claudio Pignata
Ataxia telangiectasia (AT) is a rare neurodegenerative genetic disorder due to bi-allelic mutations in the Ataxia Telangiectasia Mutated (ATM) gene. The aim of this paper is to better define the immunological profile over time, the clinical immune-re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d0677e26ad2806a0a4b840f18d5b0fe
https://hdl.handle.net/2108/314583
https://hdl.handle.net/2108/314583
Autor:
Davide Valente, Andrea Prodosmo, Luca L. Fava, Cinzia Rinaldo, Ilaria Virdia, Giuliana Di Rocco, Laura Monteonofrio, Luciana Chessa, Silvia Soddu, Antonio Musio, Claudia Contadini
Publikováno v:
Cell Death and Disease, Vol 10, Iss 11, Pp 1-16 (2019)
Cell death and disease 10 (2019). doi:10.1038/s41419-019-2076-1
info:cnr-pdr/source/autori:Contadini, Claudia; Monteonofrio, Laura; Virdia, Ilaria; Prodosmo, Andrea; Valente, Davide; Chessa, Luciana; Musio, Antonio; Fava, Luca L.; Rinaldo, Cinzia; Di Rocco, Giuliana; Soddu, Silvia/titolo:p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway/doi:10.1038%2Fs41419-019-2076-1/rivista:Cell death and disease/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Cell Death & Disease
Cell death and disease 10 (2019). doi:10.1038/s41419-019-2076-1
info:cnr-pdr/source/autori:Contadini, Claudia; Monteonofrio, Laura; Virdia, Ilaria; Prodosmo, Andrea; Valente, Davide; Chessa, Luciana; Musio, Antonio; Fava, Luca L.; Rinaldo, Cinzia; Di Rocco, Giuliana; Soddu, Silvia/titolo:p53 mitotic centrosome localization preserves centrosome integrity and works as sensor for the mitotic surveillance pathway/doi:10.1038%2Fs41419-019-2076-1/rivista:Cell death and disease/anno:2019/pagina_da:/pagina_a:/intervallo_pagine:/volume:10
Cell Death & Disease
Centrosomal p53 has been described for three decades but its role is still unclear. We previously reported that, in proliferating human cells, p53 transiently moves to centrosomes at each mitosis. Such p53 mitotic centrosome localization (p53-MCL) oc
Autor:
Giulia Federici, Mauro Magnani, Marco Malatesta, Ambra Barone, Vincenzo Leuzzi, Sara Biagiotti, Caterina Caputi, Luciana Chessa, Silvia Soddu, Mattia Paolo Aliano
Publikováno v:
Frontiers in Genetics, Vol 12 (2021)
Most of the ATM variants associated with Ataxia Telangiectasia are still classified as variants with uncertain significance. Ataxia Telangiectasia is a multisystemic disorder characterized by “typical” and “atypical” phenotypes, with early-on