Zobrazeno 1 - 10
of 45
pro vyhledávání: '"Luciana C Veiras"'
Autor:
Duo-Yao Cao, Suguru Saito, Luciana C. Veiras, Derick Okwan-Duodu, Ellen A. Bernstein, Jorge F. Giani, Kenneth E. Bernstein, Zakir Khan
Publikováno v:
Cellular & Molecular Biology Letters, Vol 25, Iss 1, Pp 1-12 (2020)
Abstract Angiotensin-converting enzyme (ACE), a dicarboxypeptidase, plays a major role in the regulation of blood pressure by cleaving angiotensin I into angiotensin II (Ang II), a potent vasoconstrictor. Because of its wide substrate specificity and
Externí odkaz:
https://doaj.org/article/94854cb79e4947a19e3ca3da80b071fd
Autor:
Zhenzi Peng, Cuiwei Liu, Aaron R. Victor, Duo-Yao Cao, Luciana C. Veiras, Ellen A. Bernstein, Zakir Khan, Jorge F. Giani, Xiaojiang Cui, Kenneth E. Bernstein, Derick Okwan-Duodu
Publikováno v:
OncoImmunology, Vol 10, Iss 1 (2021)
Granulocytes are key players in cancer metastasis. While tumor-induced de novo expansion of immunosuppressive myeloid-derived suppressor cells (MDSCs) is well-described, the fate and contribution of terminally differentiated mature neutrophils to the
Externí odkaz:
https://doaj.org/article/172498add4db402ab102601c328e4a79
Autor:
DuoYao Cao, Zakir Khan, Xiaomo Li, Suguru Saito, Ellen A Bernstein, Aaron R Victor, Faizan Ahmed, Aoi O Hoshi, Luciana C Veiras, Tomohiro Shibata, Mingtian Che, Lei Cai, Ryan E Temel, Jorge F Giani, Daniel J Luthringer, Ajit S Divakaruni, Derick Okwan-Duodu, Kenneth E Bernstein
Publikováno v:
Cardiovascular Research.
Aims The metabolic failure of macrophages to adequately process lipid is central to the etiology of atherosclerosis. Here, we examine the role of macrophage angiotensin converting enzyme (ACE) in a mouse model of PCSK9 induced atherosclerosis. Method
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0c17a66d85526fc6381a4157e1dcee78
https://doi.org/10.1093/cvr/cvad082
https://doi.org/10.1093/cvr/cvad082
Publikováno v:
Am J Physiol Cell Physiol
Kidneys continuously filter an enormous amount of sodium and adapt kidney Na+ reabsorption to match Na+ intake to maintain circulatory volume and electrolyte homeostasis. Males (M) respond to high-salt (HS) diet by translocating proximal tubule Na+/H
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53aab868024ea7ab1121a105af379877
https://doi.org/10.1152/ajpcell.00282.2021
https://doi.org/10.1152/ajpcell.00282.2021
Autor:
Tomohiro Shibata, Duo-Yao Cao, Tahir B. Dar, Faizan Ahmed, Shabir A. Bhat, Luciana C. Veiras, Ellen A. Bernstein, Abdul Arif Khan, Manita Chaum, Stephen L. Shiao, Warren G. Tourtellotte, Jorge F. Giani, Kenneth E. Bernstein, Xiaojiang Cui, Eric Vail, Zakir Khan
Publikováno v:
Cancers; Volume 14; Issue 21; Pages: 5273
Head and neck squamous cell carcinoma (HNSCC) is a highly aggressive disease with poor prognosis, which is mainly due to drug resistance. The biology determining the response to chemo-radiotherapy in HNSCC is poorly understood. Using clinical samples
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95b4ad42b859f8e09807096afa3be039
Autor:
Jorge F Giani, Luciana C Veiras, Ellen Bernstein, Duoyao Cao, Zakir Khan, Kenneth E Bernstein
Publikováno v:
Hypertension. 79
We showed that IL-1β derived from renal tubular epithelial cells initiates the inflammatory response that promotes salt sensitivity during diabetes. Yet, the intracellular mechanism that mediates IL-1β synthesis by tubular cells is unknown. We hypo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::87ba98e2fcfd8d90fc94842b70410428
https://doi.org/10.1161/hyp.79.suppl_1.p238
https://doi.org/10.1161/hyp.79.suppl_1.p238
Autor:
Duo-Yao Cao, Luciana C Veiras, Justin Z Y Shen, Derick Okwan-Duodu, Zakir Khan, Kenneth E. Bernstein, Giovanna C. Regis, Jorge F. Giani, David R Gibb, Ellen A. Bernstein, Fernando P. Dominici
Publikováno v:
J Am Soc Nephrol
Background Hypertension is considered a major risk factor for the progression of diabetic kidney disease. Type 2 diabetes is associated with increased renal sodium reabsorption and salt-sensitive hypertension. Clinical studies show that men have high
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbfdc3228ca1b094fc6bfd9ef8b98889
https://doi.org/10.1681/asn.2020081112
https://doi.org/10.1681/asn.2020081112
Autor:
Luciana C. Veiras, Ellen Bernstein, Zakir Khan, Derick Okwan, DuoYao Cao, Faizan Ahmed, David Gibb, Kenneth Bernstein, Jorge F. Giani
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2d9a60d9f00df73411b393a1433425d1
https://doi.org/10.1096/fasebj.2022.36.s1.r2774
https://doi.org/10.1096/fasebj.2022.36.s1.r2774
Autor:
Ellen A. Bernstein, Duo-Yao Cao, Kenneth E. Bernstein, Faizan Ahmed, Zakir Khan, David R Gibb, Derick Okwan, Jorge F. Giani, Luciana C Veiras
Publikováno v:
Hypertension. 78
Renal inflammation, and specifically interleukin (IL)-6, induces salt-sensitivity in diabetic mice by upregulating the epithelial sodium channel (ENaC). However, the origin of this inflammatory response is still unknown. We hypothesize that, during d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::04131152f67db55476fac17d87a6d1ba
https://doi.org/10.1161/hyp.78.suppl_1.mp32
https://doi.org/10.1161/hyp.78.suppl_1.mp32
Autor:
Warren G. Tourtellotte, Catherine Bresee, S. Ananth Karumanchi, Duo-Yao Cao, Zakir Khan, Ellen A. Bernstein, Jorge F. Giani, Faizan Ahmed, Kenneth E. Bernstein, Luciana C Veiras, Derick Okwan-Duodu
Publikováno v:
Science Translational Medicine. 13
Angiotensin-converting enzyme inhibitors (ACEIs) are used by millions of patients to treat hypertension, diabetic kidney disease, and heart failure. However, these patients are often at increased risk of infection. To evaluate the impact of ACEIs on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7949b7a848c872c3f3bd60cd12c52881
https://doi.org/10.1126/scitranslmed.abj2138
https://doi.org/10.1126/scitranslmed.abj2138