Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Luciana B Sathler"'
Autor:
Arthur A Nery, Margaret H Magdesian, Cleber A Trujillo, Luciana B Sathler, Maria A Juliano, Luiz Juliano, Henning Ulrich, Sergio T Ferreira
Publikováno v:
PLoS ONE, Vol 8, Iss 7, p e67194 (2013)
Alzheimer's disease (AD) is characterized by brain accumulation of the neurotoxic amyloid-β peptide (Aβ) and by loss of cholinergic neurons and nicotinic acetylcholine receptors (nAChRs). Recent evidence indicates that memory loss and cognitive dec
Externí odkaz:
https://doaj.org/article/ab41dddde33e43f2a52a5bf40dc26ccf
Autor:
Fernanda G. De Felice, William L. Klein, Cesar A. Silva, Paula Campello-Costa, Luciana B. Sathler, Sergio T. Ferreira, Douglas P. Munoz, Mychael V. Lourenco, Leticia Forny-Germano, Theresa R. Bomfim, Sheila Espírito Santo Araújo
Publikováno v:
Alzheimer's & Dementia. 8
Autor:
Helena Decker, Steven E. Arnold, Luciana B. Sathler, William L. Klein, Konrad Talbot, Helen M. Melo, Paula McClean, Fernanda G. De Felice, Christian Hölscher, Jean-Christophe Houzel, Hala Kazi, Douglas P. Munoz, Michael A. Silverman, Jordano Brito-Moreira, Leticia Forny-Germano, Theresa R. Bomfim, Sergio T. Ferreira
Defective brain insulin signaling has been suggested to contribute to the cognitive deficits in patients with Alzheimer's disease (AD). Although a connection between AD and diabetes has been suggested, a major unknown is the mechanism(s) by which ins
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc7f6d589af78c4c4c6e6588c323d5b3
https://europepmc.org/articles/PMC3314445/
https://europepmc.org/articles/PMC3314445/
Autor:
Luciana B. Sathler, William L. Klein, Julia R. Clarke, Rudimar Luiz Frozza, Jean-Christophe Houzel, Cesar A. Silva, Aristóbolo M. Silva, Douglas P. Munoz, Andre F. Batista, Léo Freitas-Correa, Fernanda G. De Felice, Leticia Forny-Germano, Sergio T. Ferreira, José B.C. Carvalheira, Mychael V. Lourenco, Jordano Brito-Moreira, Theresa R. Bomfim, Olavo B. Amaral, Paula Campello-Costa, Christian Hölscher, Sheila Espírito-Santo, Licio A. Velloso
Publikováno v:
Cell Metabolism. (6):831-843
SummaryAlzheimer’s disease (AD) and type 2 diabetes appear to share similar pathogenic mechanisms. dsRNA-dependent protein kinase (PKR) underlies peripheral insulin resistance in metabolic disorders. PKR phosphorylates eukaryotic translation initia