Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Lucian Soane"'
Publikováno v:
PLoS Biology, Vol 10, Iss 9, p e1001399 (2012)
Cell death by apoptosis is indispensable for proper development and tissue homeostasis in all multicellular organisms, and its deregulation plays a key role in cancer and many other diseases. A crucial event in apoptosis is the formation of protein-p
Externí odkaz:
https://doaj.org/article/d06e94dfc07a43579177eb136fbb76e8
Autor:
Lucian Soane, Loïc Lionnard, J. Marie Hardwick, Xinchen Teng, Abdel Aouacheria, Kyle Metz, Atsushi Kamiya
Publikováno v:
CNS Neuroscience & Therapeutics
CNS Neuroscience and Therapeutics
CNS Neuroscience and Therapeutics, 2019, 25 (7), pp.887-902. ⟨10.1111/cns.13156⟩
CNS Neuroscience and Therapeutics, Wiley, 2019, 25 (7), pp.887-902. ⟨10.1111/cns.13156⟩
CNS Neuroscience and Therapeutics
CNS Neuroscience and Therapeutics, 2019, 25 (7), pp.887-902. ⟨10.1111/cns.13156⟩
CNS Neuroscience and Therapeutics, Wiley, 2019, 25 (7), pp.887-902. ⟨10.1111/cns.13156⟩
International audience; The underlying molecular basis for neurodevelopmental or neuropsychiatric disorders is not known. In contrast, mechanistic understanding of other brain disorders including neurodegeneration has advanced considerably. Yet, thes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16a3c49cfbd1d479db3055f218facc2d
http://europepmc.org/articles/PMC6566181
http://europepmc.org/articles/PMC6566181
Publikováno v:
Journal of Neuroscience Research. 85:3407-3415
Altered mitochondrial energy metabolism contributes to the pathophysiology of acute brain injury caused by ischemia, trauma, and neurotoxins and by chronic neurodegenerative disorders such as Parkinson’s and Huntington’s diseases. Although much e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b2e5d63c259d6e6f7cc1903cf7bf6bbc
https://doi.org/10.1002/jnr.21498
https://doi.org/10.1002/jnr.21498
Autor:
Lucian Soane, Gary Fiskum
Publikováno v:
Journal of Neurochemistry. 95:230-243
Protein delivery mediated by protein transduction domains (PTD) such as the HIV-1 TAT-PTD has emerged as a promising approach for neuroprotection. The objective of this study was to generate and evaluate the neuroprotective potential of TAT fusion pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5f66810d60cd7834d6141c5c1c84c308
https://doi.org/10.1111/j.1471-4159.2005.03359.x
https://doi.org/10.1111/j.1471-4159.2005.03359.x
Autor:
Lucian Soane, Gary Fiskum
Publikováno v:
Journal of Bioenergetics and Biomembranes. 37:179-190
Bcl-2 and other closely related members of the Bcl-2 family of proteins inhibit the death of neurons and many other cells in response to a wide variety of pathogenic stimuli. Bcl-2 inhibition of apoptosis is mediated by its binding to pro-apoptotic p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a7a3e7a01baff4d837b0f06db967cd3
https://doi.org/10.1007/s10863-005-6590-8
https://doi.org/10.1007/s10863-005-6590-8
Autor:
Susanna Weerth, Teodora Niculescu, Florin Niculescu, Moon L. Shin, Lucian Soane, Cedric S. Raine, Violeta Rus, Horea Rus
Publikováno v:
Annals of the New York Academy of Sciences. 1010:530-533
Complement activation is involved in the initiation of inflammation and antibody-mediated demyelination in experimental autoimmune encephalomyelitis (EAE). We investigated the role of MAC in apoptosis in myelin-induced EAE in complement C5-deficient
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbfaa9d9d534b675a3c895115cf76020
https://doi.org/10.1196/annals.1299.098
https://doi.org/10.1196/annals.1299.098
Autor:
Teodora Niculescu, Moon L. Shin, Jae-Hyun Park, Lucian Soane, Tudor Badea, Horea Rus, Florin Niculescu
Publikováno v:
Journal of Neuroimmunology. 142:58-66
Sublytic C5b-9 alters the molecular phenotype of myotubes by inhibiting muscle-specific gene expression. Here, we showed that C5b-9 induced c-fos mRNA and transcription. Using c-fos promoter-CAT constructs and electrophoretic mobility shift assay (EM
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7441d21488fc4316fb9b82bbc047eb87
https://doi.org/10.1016/s0165-5728(03)00261-3
https://doi.org/10.1016/s0165-5728(03)00261-3
Autor:
Florin Niculescu, Hila Sorana, Violeta Rus, Horea Rus, Lucian Soane, Matthew Fosbrink, Tudor C. Badea, Moon L. Shin
Publikováno v:
Journal of Biological Chemistry. 277:502-508
Proliferation of aortic smooth muscle cells contributes to atherogenesis and neointima formation. Sublytic activation of complement, particularly C5b-9, induces cell cycle progression in aortic smooth muscle cells. RGC-32 is a novel protein that may
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d0c5b85561772cd72a91415f95b3b02
https://doi.org/10.1074/jbc.m109354200
https://doi.org/10.1074/jbc.m109354200
Publikováno v:
The Journal of Immunology. 167:2305-2311
Apoptosis of oligodendrocytes is induced by serum growth factor deprivation. We showed that oligodendrocytes and progenitor cells respond to serum withdrawal by a rapid decline of Bcl-2 mRNA expression and caspase-3-dependent apoptotic death. Sublyti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0f32b18a1427044ccfdf1d0b0407ed7
https://doi.org/10.4049/jimmunol.167.4.2305
https://doi.org/10.4049/jimmunol.167.4.2305
Publikováno v:
Journal of Biological Chemistry. 273:26977-26981
Sublytic complement activation on oligodendrocytes (OLG) down-regulates expression of myelin genes and induces cell cycle in culture. Differential display (DD) was used to search for new genes whose expression is altered in response to complement and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c506de325ba6def00e27c415cc866b
https://doi.org/10.1074/jbc.273.41.26977
https://doi.org/10.1074/jbc.273.41.26977