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pro vyhledávání: '"Lucia Petrova"'
Abstract 289: MET activation mediates lapatinib resistance in experimental esophageal adenocarcinoma
Autor:
Md Sazzad Hassan, Fiona Williams, Lucia Petrova, Niranjan Awasthi, Margaret Schwarz, Roderich Schwarz, Urs von Holzen
Publikováno v:
Cancer Research. 79:289-289
Introduction: A major target for esophageal adenocarcinoma (EAC) therapies is the human epidermal growth factor receptor 2 (HER2). Unfortunately, patients treated with lapatinib, a dual EGFR and HER2 inhibitor, frequently develop resistance. Lapatini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4085737e733acad8314c8a62c494b3d6
https://doi.org/10.1158/1538-7445.am2019-289
https://doi.org/10.1158/1538-7445.am2019-289
Publikováno v:
Cancer Research. 79:1230-1230
Introduction: Esophageal adenocarcinoma (EAC) has become the predominant type of esophageal cancer in the United States, and prognosis of EAC remains poor despite modern combination therapies. Therefore, new therapeutic approaches are urgently needed
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::faee33415e50098da9a9028c106f1711
https://doi.org/10.1158/1538-7445.am2019-1230
https://doi.org/10.1158/1538-7445.am2019-1230