Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Lucia M. Malone"'
Autor:
Suzanne L. Warring, Lucia M. Malone, Jay Jayaraman, Richard A. Easingwood, Luciano A. Rigano, Rebekah A. Frampton, Sandra B. Visnovsky, Shea M. Addison, Loreto Hernandez, Andrew R. Pitman, Elena Lopez Acedo, Torsten Kleffmann, Matthew D. Templeton, Mihnea Bostina, Peter C. Fineran
Publikováno v:
Environmental Microbiology. 24:4834-4852
SummaryBacterial pathogens are major causes of crop diseases, leading to significant production losses. For instance, kiwifruit canker, caused by the phytopathogen Pseudomonas syringae pv. actinidiae (Psa), has posed a global challenge to kiwifruit p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ee14c7bf4a1194d73002d9cd0dc4efd
https://doi.org/10.1111/1462-2920.16106
https://doi.org/10.1111/1462-2920.16106
Autor:
Marina Mahler, Lucia M. Malone, Daan F. van den Berg, Leah M. Smith, Stan J. J. Brouns, Peter C. Fineran
Publikováno v:
Microbial Genomics, 9(3)
Serratia sp. ATCC 39006 is a Gram-negative bacterium that has been used to study the function of phage defences, such as CRISPR–Cas, and phage counter-defence mechanisms. To expand our phage collection to study the phage–host interaction with Ser
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d693b43f16a0c24bf63b63397dc48571
https://doi.org/10.1099/mgen.0.000968
https://doi.org/10.1099/mgen.0.000968
Publikováno v:
Nucleic Acids Research
During infection, phages manipulate bacteria to redirect metabolism towards viral proliferation. To counteract phages, some bacteria employ CRISPR-Cas systems that provide adaptive immunity. While CRISPR-Cas mechanisms have been studied extensively,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a7869b5c56bf85d4e9d6d00fef67160f
https://doi.org/10.1093/nar/gkab1210
https://doi.org/10.1093/nar/gkab1210
Autor:
David Mayo-Muñoz, Leah M. Smith, Carmela Garcia-Doval, Lucia M. Malone, Kate R. Harding, Simon A. Jackson, Hannah G. Hampton, Robert D. Fagerlund, Laura F. Gumy, Peter C. Fineran
Publikováno v:
Molecular cell. 82(23)
Bacteria have diverse defenses against phages. In response, jumbo phages evade multiple DNA-targeting defenses by protecting their DNA inside a nucleus-like structure. We previously demonstrated that RNA-targeting type III CRISPR-Cas systems provide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c98df0f42e20416c2589d3df0fdfb5b
https://pubmed.ncbi.nlm.nih.gov/36395770
https://pubmed.ncbi.nlm.nih.gov/36395770
Autor:
David Mayo-Muñoz, Leah M. Smith, Carmela Garcia-Doval, Lucia M. Malone, Kate R. Harding, Simon A. Jackson, Hannah G. Hampton, Robert D. Fagerlund, Laura F. Gumy, Peter C. Fineran
SUMMARYBacteria have diverse defences against phages. In response, jumbo phages evade multiple DNA-targeting defences by protecting their DNA inside a nucleus-like structure. We previously demonstrated that RNA-targeting type III CRISPR–Cas systems
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d25c732267ebf603486423ff2f6b5983
https://doi.org/10.1101/2022.06.20.496707
https://doi.org/10.1101/2022.06.20.496707
Autor:
Lucia M. Malone, James E. Ussher, Leah M Smith, Peter C. Fineran, Paul P. Gardner, Simon A. Jackson
Publikováno v:
Nature Microbiology. 6:162-172
Bacteria harbour multiple innate defences and adaptive CRISPR-Cas systems that provide immunity against bacteriophages and mobile genetic elements. Although some bacteria modulate defences in response to population density, stress and metabolic state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bdac363505f4588f65068d20f6abd11c
https://doi.org/10.1038/s41564-020-00822-7
https://doi.org/10.1038/s41564-020-00822-7
Autor:
Peter C. Fineran, Carolin Warnecke, Simon A. Jackson, Suzanne L. Warring, Paul P. Gardner, Laura F. Gumy, Lucia M. Malone
Publikováno v:
Nature Microbiology. 5:48-55
CRISPR–Cas systems provide bacteria with adaptive immunity against bacteriophages1. However, DNA modification2,3, the production of anti-CRISPR proteins4,5 and potentially other strategies enable phages to evade CRISPR–Cas. Here, we discovered a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1377bbe87eb8c521e75bc0d7da729e2b
https://doi.org/10.1038/s41564-019-0612-5
https://doi.org/10.1038/s41564-019-0612-5
Autor:
Leah M, Smith, Simon A, Jackson, Lucia M, Malone, James E, Ussher, Paul P, Gardner, Peter C, Fineran
Publikováno v:
Nature microbiology. 6(2)
Bacteria harbour multiple innate defences and adaptive CRISPR-Cas systems that provide immunity against bacteriophages and mobile genetic elements. Although some bacteria modulate defences in response to population density, stress and metabolic state
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7f852e88ade9f164006582d56941f48f
https://pubmed.ncbi.nlm.nih.gov/33510433
https://pubmed.ncbi.nlm.nih.gov/33510433
Publikováno v:
Current opinion in biotechnology. 68
The rise of antibiotic-resistant bacteria has led to renewed interest in the use of their natural enemies, phages, for the prevention and treatment of infections. However, phage therapy requires detailed knowledge of the interactions between these en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63f1595ba37f978de47dd41b858fbc5d
https://pubmed.ncbi.nlm.nih.gov/33113496
https://pubmed.ncbi.nlm.nih.gov/33113496
Autor:
Lucia M, Malone, Suzanne L, Warring, Simon A, Jackson, Carolin, Warnecke, Paul P, Gardner, Laura F, Gumy, Peter C, Fineran
Publikováno v:
Nature microbiology. 5(1)
CRISPR-Cas systems provide bacteria with adaptive immunity against bacteriophages
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9e591a892e06ba55b055b733956527c7
https://pubmed.ncbi.nlm.nih.gov/32142691
https://pubmed.ncbi.nlm.nih.gov/32142691